STRINGSTRING
I3LZW4_ICTTR I3LZW4_ICTTR MAPK10 MAPK10 LOC101954381 LOC101954381 PPP2R1A PPP2R1A PPP4R4 PPP4R4 MAPK3 MAPK3 MAPK7 MAPK7 TRAF6 TRAF6 MAP3K7 MAP3K7 RPS6KA1 RPS6KA1 ENSSTOP00000031366 ENSSTOP00000031366 MAPK9 MAPK9 MAP2K7 MAP2K7 MAPKAPK3 MAPKAPK3 ENSSTOP00000029566 ENSSTOP00000029566 TAB3 TAB3 RPS6KA5 RPS6KA5 ENSSTOP00000028911 ENSSTOP00000028911 ENSSTOP00000028703 ENSSTOP00000028703 LOC101954990 LOC101954990 VRK3 VRK3 ENSSTOP00000027631 ENSSTOP00000027631 Ppp2cb Ppp2cb ENSSTOP00000027318 ENSSTOP00000027318 IKBKG IKBKG CREB5 CREB5 PPP2R1B PPP2R1B IRAK1 IRAK1 MAPK14 MAPK14 JUN JUN FOSL2 FOSL2 PPP2R5D PPP2R5D CCDC71L CCDC71L LOC101966763 LOC101966763 MAP2K4 MAP2K4 MAPK15 MAPK15 NOD2 NOD2 NOD1 NOD1 PPP4R1 PPP4R1 RELCH RELCH TAB2 TAB2 CREB1 CREB1 MAPK11 MAPK11 RIPK2 RIPK2 MAPK1 MAPK1 UBE2V1 UBE2V1 FNBP4 FNBP4 ATF2 ATF2 IRAK2 IRAK2 Dusp3 Dusp3 MAPK8 MAPK8 NFKB1 NFKB1 ATF1 ATF1 PPP2CA PPP2CA RPS6KA3 RPS6KA3 ELK1 ELK1 DUSP4 DUSP4 MAP2K3 MAP2K3 Rps27a Rps27a Map3k20 Map3k20 Atf7 Atf7 MAPKAPK2 MAPKAPK2 DUSP6 DUSP6 RPS6KA2 RPS6KA2 UBA52 UBA52 FOS FOS TAB1 TAB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I3LZW4_ICTTRUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (129 aa)
MAPK10Mitogen-activated protein kinase. (492 aa)
LOC101954381UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (176 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (835 aa)
MAPK3Mitogen-activated protein kinase. (361 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (812 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (469 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
ENSSTOP00000029566UBIQUITIN_CONJUGAT_2 domain-containing protein. (122 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (717 aa)
RPS6KA5Ribosomal protein S6 kinase. (859 aa)
ENSSTOP00000028911UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (203 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
LOC101954990Tyrosine-protein phosphatase domain-containing protein. (231 aa)
VRK3VRK serine/threonine kinase 3. (453 aa)
ENSSTOP00000027631SER_THR_PHOSPHATASE domain-containing protein. (235 aa)
Ppp2cbSerine/threonine-protein phosphatase. (274 aa)
ENSSTOP00000027318BZIP domain-containing protein. (133 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (492 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (467 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (658 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (715 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (603 aa)
CCDC71LUncharacterized protein. (176 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (360 aa)
MAPK15Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (554 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1014 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (951 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (934 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1217 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (692 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MAPK11Mitogen-activated protein kinase. (325 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
MAPK1Mitogen-activated protein kinase. (331 aa)
UBE2V1Ubiquitin conjugating enzyme E2 V1. (139 aa)
FNBP4Formin binding protein 4. (1071 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (616 aa)
Dusp3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (211 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
NFKB1Nuclear factor kappa B subunit 1. (985 aa)
ATF1Activating transcription factor 1. (269 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
ELK1ETS transcription factor ELK1. (428 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
Map3k20Uncharacterized protein. (800 aa)
Atf7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (358 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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