23 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	RSPO1	R-spondin 1. (236 aa)
	USP8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1097 aa)
	FZD6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (711 aa)
	LRTM1	Leucine rich repeats and transmembrane domains 1. (345 aa)
	Rps27a	Ubiquitin-like domain-containing protein. (156 aa)
	LRP5	Uncharacterized protein. (1516 aa)
	RSPO4	R-spondin 4. (233 aa)
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1540 aa)
	FZD4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
	LGR6	Leucine rich repeat containing G protein-coupled receptor 6. (967 aa)
	FZD5	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	LOC101966763	Ubiquitin-like domain-containing protein. (156 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	RSPO2	R-spondin 2. (243 aa)
	ZNRF3	Zinc and ring finger 3. (823 aa)
	FZD8	Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (470 aa)
	RSPO3	R-spondin 3. (275 aa)
	LGR5	Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
	LGR4	Leucine rich repeat containing G protein-coupled receptor 4. (927 aa)
	ENSSTOP00000028703	Ubiquitin-like domain-containing protein. (122 aa)
	Rnf43	RING-type domain-containing protein. (779 aa)
	ENSSTOP00000031366	Ubiquitin-like domain-containing protein. (95 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSTOP00000028703	ENSSTOP00000031366	ENSSTOP00000028703	ENSSTOP00000031366	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.985
ENSSTOP00000028703	LOC101966763	ENSSTOP00000028703	ENSSTOP00000019666	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.985
ENSSTOP00000028703	Rnf43	ENSSTOP00000028703	ENSSTOP00000030394	Ubiquitin-like domain-containing protein.	RING-type domain-containing protein.	0.720
ENSSTOP00000028703	Rps27a	ENSSTOP00000028703	ENSSTOP00000008580	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.985
ENSSTOP00000028703	USP8	ENSSTOP00000028703	ENSSTOP00000005307	Ubiquitin-like domain-containing protein.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.924
ENSSTOP00000028703	ZNRF3	ENSSTOP00000028703	ENSSTOP00000022456	Ubiquitin-like domain-containing protein.	Zinc and ring finger 3.	0.632
ENSSTOP00000031366	ENSSTOP00000028703	ENSSTOP00000031366	ENSSTOP00000028703	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.985
ENSSTOP00000031366	FZD4	ENSSTOP00000031366	ENSSTOP00000015378	Ubiquitin-like domain-containing protein.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.636
ENSSTOP00000031366	FZD5	ENSSTOP00000031366	ENSSTOP00000017584	Ubiquitin-like domain-containing protein.	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.	0.557
ENSSTOP00000031366	FZD6	ENSSTOP00000031366	ENSSTOP00000007122	Ubiquitin-like domain-containing protein.	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.	0.647
ENSSTOP00000031366	FZD8	ENSSTOP00000031366	ENSSTOP00000022537	Ubiquitin-like domain-containing protein.	Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family.	0.557
ENSSTOP00000031366	LGR4	ENSSTOP00000031366	ENSSTOP00000028354	Ubiquitin-like domain-containing protein.	Leucine rich repeat containing G protein-coupled receptor 4.	0.689
ENSSTOP00000031366	LGR5	ENSSTOP00000031366	ENSSTOP00000024838	Ubiquitin-like domain-containing protein.	Leucine rich repeat containing G protein-coupled receptor 5.	0.689
ENSSTOP00000031366	LRP5	ENSSTOP00000031366	ENSSTOP00000011017	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.561
ENSSTOP00000031366	LRP6	ENSSTOP00000031366	ENSSTOP00000013745	Ubiquitin-like domain-containing protein.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.587
ENSSTOP00000031366	LRTM1	ENSSTOP00000031366	ENSSTOP00000007609	Ubiquitin-like domain-containing protein.	Leucine rich repeats and transmembrane domains 1.	0.535
ENSSTOP00000031366	Rnf43	ENSSTOP00000031366	ENSSTOP00000030394	Ubiquitin-like domain-containing protein.	RING-type domain-containing protein.	0.700
ENSSTOP00000031366	UBA52	ENSSTOP00000031366	ENSSTOP00000004191	Ubiquitin-like domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.985
ENSSTOP00000031366	USP8	ENSSTOP00000031366	ENSSTOP00000005307	Ubiquitin-like domain-containing protein.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.915
ENSSTOP00000031366	ZNRF3	ENSSTOP00000031366	ENSSTOP00000022456	Ubiquitin-like domain-containing protein.	Zinc and ring finger 3.	0.494