STRINGSTRING
ENSSTOP00000031310 ENSSTOP00000031310 ENSSTOP00000032525 ENSSTOP00000032525 LOC101978532 LOC101978532 ENSSTOP00000031366 ENSSTOP00000031366 ENSSTOP00000026616 ENSSTOP00000026616 TNFSF10 TNFSF10 Birc2 Birc2 BIRC3 BIRC3 CHMP4B CHMP4B UBA52 UBA52 Casp3 Casp3 XIAP XIAP PDCD6IP PDCD6IP FLOT2 FLOT2 RIPK3 RIPK3 IL1B IL1B IL1A IL1A RIPK1 RIPK1 IRF2 IRF2 ENSSTOP00000026081 ENSSTOP00000026081 MLKL MLKL ENSSTOP00000025685 ENSSTOP00000025685 CFLAR CFLAR Hmgb1 Hmgb1 ENSSTOP00000027174 ENSSTOP00000027174 CHMP4A CHMP4A ENSSTOP00000028611 ENSSTOP00000028611 ENSSTOP00000028703 ENSSTOP00000028703 BAK1 BAK1 BIRC7 BIRC7 ENSSTOP00000030003 ENSSTOP00000030003 FADD FADD FLOT1 FLOT1 LOC101977635 LOC101977635 Chmp2a Chmp2a LOC101964473 LOC101964473 I3NC87_ICTTR I3NC87_ICTTR I3NBU5_ICTTR I3NBU5_ICTTR CASP10 CASP10 GSDMD GSDMD Chmp3 Chmp3 LOC101978189 LOC101978189 LOC101966763 LOC101966763 LOC101977364 LOC101977364 CHMP6 CHMP6 LOC101976153 LOC101976153 PRKN PRKN LOC101973046 LOC101973046 LOC101959922 LOC101959922 I3MXS4_ICTTR I3MXS4_ICTTR PELI1 PELI1 MDP1 MDP1 STUB1 STUB1 Naip Naip IL18 IL18 Ube2l3 Ube2l3 CDC37 CDC37 CHMP7 CHMP7 Gsdme Gsdme BAX BAX CHMP4C CHMP4C TRAF2 TRAF2 OGT OGT CHMP2B CHMP2B TRADD TRADD CASP8 CASP8 IRF1 IRF1 Rps27a Rps27a NPVF NPVF LOC106144614 LOC106144614 SDCBP SDCBP LOC101954543 LOC101954543 Faslg Faslg LOC101966186 LOC101966186
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSSTOP00000031310Uncharacterized protein; Belongs to the peptidase C14A family. (233 aa)
ENSSTOP00000032525Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (94 aa)
LOC101978532Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (100 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
ENSSTOP00000026616Uncharacterized protein. (174 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (296 aa)
Birc2Uncharacterized protein. (611 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
Casp3Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
PDCD6IPProgrammed cell death 6 interacting protein. (875 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
RIPK3Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (491 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (200 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (268 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (665 aa)
IRF2Interferon regulatory factor 2. (353 aa)
ENSSTOP00000026081Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
MLKLMixed lineage kinase domain like pseudokinase. (472 aa)
ENSSTOP00000025685Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (106 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (488 aa)
Hmgb1Uncharacterized protein. (188 aa)
ENSSTOP00000027174Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (101 aa)
CHMP4ACharged multivesicular body protein 4A. (259 aa)
ENSSTOP00000028611Uncharacterized protein. (195 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
BAK1BCL2 antagonist/killer 1. (208 aa)
BIRC7Baculoviral IAP repeat containing 7. (304 aa)
ENSSTOP00000030003Uncharacterized protein. (546 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
LOC101977635Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (255 aa)
Chmp2aUncharacterized protein. (222 aa)
LOC101964473Uncharacterized protein; Belongs to the peptidase C14A family. (376 aa)
I3NC87_ICTTRCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
I3NBU5_ICTTRUncharacterized protein. (209 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (480 aa)
GSDMDGasdermin D. (489 aa)
Chmp3Uncharacterized protein. (208 aa)
LOC101978189Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
LOC101977364Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (255 aa)
CHMP6Charged multivesicular body protein 6. (201 aa)
LOC101976153Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (463 aa)
LOC101973046Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa)
LOC101959922Uncharacterized protein. (442 aa)
I3MXS4_ICTTRCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
MDP1Uncharacterized protein. (164 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
NaipNACHT domain-containing protein. (1405 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
Ube2l3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
CDC37Cell division cycle 37. (378 aa)
CHMP7Charged multivesicular body protein 7. (445 aa)
GsdmeGasdermin domain-containing protein. (123 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
TRADDTNFRSF1A associated via death domain. (302 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (520 aa)
IRF1Interferon regulatory factor. (326 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
NPVFNeuropeptide VF precursor. (192 aa)
LOC106144614Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
SDCBPSyndecan binding protein. (298 aa)
LOC101954543Uncharacterized protein; Belongs to the peptidase C14A family. (365 aa)
FaslgTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (69 aa)
LOC101966186Uncharacterized protein. (159 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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