STRINGSTRING
CHUK CHUK XIAP XIAP UBA52 UBA52 SPPL2A SPPL2A USP2 USP2 BIRC3 BIRC3 Birc2 Birc2 IKBKB IKBKB MAPKAPK2 MAPKAPK2 USP21 USP21 RACK1 RACK1 UBE2D1 UBE2D1 TNFAIP3 TNFAIP3 TBK1 TBK1 CLIP3 CLIP3 Rps27a Rps27a TNFRSF1A TNFRSF1A CYLD CYLD ULK1 ULK1 OTULIN OTULIN Rnf31 Rnf31 UBE2D4 UBE2D4 SHARPIN SHARPIN CLIP4 CLIP4 NFATC4 NFATC4 TAX1BP1 TAX1BP1 SPATA2 SPATA2 STUB1 STUB1 Naip Naip USP4 USP4 CASP8 CASP8 LOC101976087 LOC101976087 TRADD TRADD TRAF2 TRAF2 TMEM198 TMEM198 OTULINL OTULINL Ube2l3 Ube2l3 SPPL2B SPPL2B CFLAR CFLAR ULK2 ULK2 FADD FADD Ikbke Ikbke I3NGQ5_ICTTR I3NGQ5_ICTTR TRAF1 TRAF1 CASP10 CASP10 LOC101955860 LOC101955860 MADD MADD OTUD7B OTUD7B LOC101966763 LOC101966763 SPPL2C SPPL2C RBCK1 RBCK1 I3MW74_ICTTR I3MW74_ICTTR WDR31 WDR31 RIPK1 RIPK1 Ube2d3 Ube2d3 ENSSTOP00000031366 ENSSTOP00000031366 ENSSTOP00000031129 ENSSTOP00000031129 ENSSTOP00000030003 ENSSTOP00000030003 BIRC7 BIRC7 ENSSTOP00000028703 ENSSTOP00000028703 UBE2D2 UBE2D2 IKBKG IKBKG ENSSTOP00000026209 ENSSTOP00000026209
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (769 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
SPPL2ASignal peptide peptidase like 2A. (502 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (612 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
Birc2Uncharacterized protein. (611 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (358 aa)
USP21Ubiquitin specific peptidase 21; Belongs to the peptidase C19 family. (567 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
TNFAIP3TNF alpha induced protein 3. (776 aa)
TBK1TANK binding kinase 1. (729 aa)
CLIP3CAP-Gly domain containing linker protein 3. (547 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
TNFRSF1ATNF receptor superfamily member 1A. (437 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1041 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (311 aa)
Rnf31Uncharacterized protein. (1071 aa)
UBE2D4Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (144 aa)
SHARPINSHANK associated RH domain interactor. (382 aa)
CLIP4CAP-Gly domain containing linker protein family member 4. (527 aa)
NFATC4Nuclear factor of activated T cells 4. (890 aa)
TAX1BP1Tax1 binding protein 1. (777 aa)
SPATA2Spermatogenesis associated 2. (509 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
NaipNACHT domain-containing protein. (1405 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (963 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (520 aa)
LOC101976087DUF4203 domain-containing protein. (351 aa)
TRADDTNFRSF1A associated via death domain. (302 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
TMEM198Transmembrane protein 198. (360 aa)
OTULINLOTU deubiquitinase with linear linkage specificity like. (284 aa)
Ube2l3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
SPPL2BSignal peptide peptidase like 2B. (590 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (488 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1058 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
IkbkeProtein kinase domain-containing protein. (130 aa)
I3NGQ5_ICTTRUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
TRAF1TNF receptor-associated factor. (415 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (480 aa)
LOC101955860CCHC NOA-type domain-containing protein. (505 aa)
MADDMAP kinase activating death domain. (1597 aa)
OTUD7BOTU deubiquitinase 7B. (843 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
SPPL2CSignal peptide peptidase like 2C. (677 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (536 aa)
I3MW74_ICTTRUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
WDR31WD repeat domain 31. (367 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (665 aa)
Ube2d3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
ENSSTOP00000031129Uncharacterized protein. (71 aa)
ENSSTOP00000030003Uncharacterized protein. (546 aa)
BIRC7Baculoviral IAP repeat containing 7. (304 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (143 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (492 aa)
ENSSTOP00000026209UBIQUITIN_CONJUGAT_2 domain-containing protein. (89 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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