STRINGSTRING
TAB1 TAB1 PSMD4 PSMD4 LOC101954381 LOC101954381 PSMB2 PSMB2 PSMB10 PSMB10 I3LZW4_ICTTR I3LZW4_ICTTR NFKB2 NFKB2 IL1B IL1B UBA3 UBA3 PSMB9 PSMB9 PSMD10 PSMD10 PRKCD PRKCD UBA52 UBA52 PSMC2 PSMC2 PLCG2 PLCG2 IKBKB IKBKB CUL1 CUL1 PSMA1 PSMA1 PSMB5 PSMB5 UBE2D1 UBE2D1 TRAF6 TRAF6 Card11 Card11 NFATC1 NFATC1 PSME4 PSME4 Psmc5 Psmc5 Map3k20 Map3k20 PSMD1 PSMD1 Rps27a Rps27a PSMB1 PSMB1 PSMC3 PSMC3 CASP8 CASP8 Psmd9 Psmd9 NFKB1 NFKB1 Psma6 Psma6 PPP3CA PPP3CA PSMB4 PSMB4 PSMA7 PSMA7 PSMC4 PSMC4 PSMD6 PSMD6 PDPK1 PDPK1 PSMD5 PSMD5 PSMD7 PSMD7 PSMA2 PSMA2 PYCARD PYCARD PSMA3 PSMA3 PSMB7 PSMB7 CARD9 CARD9 UBE2V1 UBE2V1 PSMD8 PSMD8 Psmc6 Psmc6 Psmb6 Psmb6 PSMD14 PSMD14 PSMA8 PSMA8 CHUK CHUK Ppp3r1 Ppp3r1 TAB2 TAB2 NFATC3 NFATC3 PSMB11 PSMB11 NFAT5 NFAT5 MALT1 MALT1 I3N1R8_ICTTR I3N1R8_ICTTR LOC101966763 LOC101966763 WDR92 WDR92 CCDC71L CCDC71L PSMB8 PSMB8 BCL10 BCL10 BTRC BTRC CASP10 CASP10 LOC101967492 LOC101967492 UBE2M UBE2M FBXW11 FBXW11 PSMD3 PSMD3 PSMF1 PSMF1 PSMB3 PSMB3 ENSSTOP00000024305 ENSSTOP00000024305 PSMD13 PSMD13 LOC101972090 LOC101972090 PSMD2 PSMD2 ENSSTOP00000025153 ENSSTOP00000025153 PSME1 PSME1 PSME3 PSME3 RELB RELB PSMA5 PSMA5 PSMD11 PSMD11 IKBKG IKBKG PSME2 PSME2 Clec7a Clec7a ENSSTOP00000027615 ENSSTOP00000027615 UBE2D2 UBE2D2 ENSSTOP00000028703 ENSSTOP00000028703 PSMA4 PSMA4 ENSSTOP00000028911 ENSSTOP00000028911 NFATC2 NFATC2 TAB3 TAB3 ENSSTOP00000029537 ENSSTOP00000029537 ENSSTOP00000029566 ENSSTOP00000029566 ENSSTOP00000030001 ENSSTOP00000030001 SKP1 SKP1 MAP3K14 MAP3K14 ENSSTOP00000031366 ENSSTOP00000031366 PSMD12 PSMD12 Psmc1 Psmc1 ENSSTOP00000031690 ENSSTOP00000031690 MAP3K7 MAP3K7 PPP3CB PPP3CB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
LOC101954381UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (176 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMB10Proteasome subunit beta. (273 aa)
I3LZW4_ICTTRUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (129 aa)
NFKB2Nuclear factor kappa B subunit 2. (899 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (200 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (450 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMD10ANK_REP_REGION domain-containing protein. (226 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMA1Proteasome subunit alpha type. (266 aa)
PSMB5Proteasome subunit beta. (220 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa)
Card11Uncharacterized protein. (1152 aa)
NFATC1Nuclear factor of activated T cells 1. (941 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
Psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
Map3k20Uncharacterized protein. (800 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
PSMB1Proteasome subunit beta. (240 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (520 aa)
Psmd9PDZ domain-containing protein. (223 aa)
NFKB1Nuclear factor kappa B subunit 1. (985 aa)
Psma6Proteasome subunit alpha type. (148 aa)
PPP3CASerine/threonine-protein phosphatase. (511 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (556 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PYCARDPYD and CARD domain containing. (194 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMB7Proteasome subunit beta. (277 aa)
CARD9Caspase recruitment domain family member 9. (537 aa)
UBE2V1Ubiquitin conjugating enzyme E2 V1. (139 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
Psmc626S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa)
Psmb6Proteasome subunit beta. (239 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMA8Proteasome subunit alpha type. (257 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (769 aa)
Ppp3r1Uncharacterized protein. (169 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (692 aa)
NFATC3Nuclear factor of activated T cells 3. (1075 aa)
PSMB11Proteasome subunit beta. (293 aa)
NFAT5Nuclear factor of activated T cells 5. (1526 aa)
MALT1MALT1 paracaspase. (747 aa)
I3N1R8_ICTTRUncharacterized protein. (199 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
WDR92WD repeat domain 92. (357 aa)
CCDC71LUncharacterized protein. (176 aa)
PSMB8Proteasome subunit beta. (276 aa)
BCL10BCL10 immune signaling adaptor. (153 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (480 aa)
LOC101967492Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
UBE2MUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
FBXW11F-box and WD repeat domain containing 11. (553 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSSTOP00000024305Uncharacterized protein. (210 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
LOC101972090AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
ENSSTOP00000025153PROTEASOME_ALPHA_1 domain-containing protein. (87 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSME3Proteasome activator subunit 3. (254 aa)
RELBRELB proto-oncogene, NF-kB subunit. (567 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (492 aa)
PSME2Proteasome activator subunit 2. (239 aa)
Clec7aUncharacterized protein. (157 aa)
ENSSTOP00000027615Uncharacterized protein. (247 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (143 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
ENSSTOP00000028911UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (203 aa)
NFATC2Nuclear factor of activated T cells 2. (844 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (717 aa)
ENSSTOP00000029537Proteasome subunit beta. (200 aa)
ENSSTOP00000029566UBIQUITIN_CONJUGAT_2 domain-containing protein. (122 aa)
ENSSTOP00000030001AAA domain-containing protein. (334 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (934 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
Psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ENSSTOP00000031690ANK_REP_REGION domain-containing protein. (189 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
PPP3CBSerine/threonine-protein phosphatase. (523 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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