STRINGSTRING
PSMB2 PSMB2 PSMD4 PSMD4 PSMD7 PSMD7 PSMA2 PSMA2 PSMA3 PSMA3 PSMB7 PSMB7 PSMD8 PSMD8 Psmc6 Psmc6 Psmb6 Psmb6 PSMD14 PSMD14 Rbx1 Rbx1 PSMA8 PSMA8 PSMB11 PSMB11 LOC101957545 LOC101957545 I3N110_ICTTR I3N110_ICTTR I3N1R8_ICTTR I3N1R8_ICTTR LOC101966763 LOC101966763 PSMB8 PSMB8 Psmc1 Psmc1 PSMD12 PSMD12 ENSSTOP00000031366 ENSSTOP00000031366 CSNK1A1 CSNK1A1 BTRC BTRC SKP1 SKP1 ENSSTOP00000030001 ENSSTOP00000030001 ENSSTOP00000029537 ENSSTOP00000029537 PRKACB PRKACB ENSSTOP00000031690 ENSSTOP00000031690 Psmd9 Psmd9 Psma6 Psma6 PSMB4 PSMB4 PSMA4 PSMA4 ENSSTOP00000028717 ENSSTOP00000028717 ENSSTOP00000028703 ENSSTOP00000028703 PSME2 PSME2 PSMD11 PSMD11 PSMA5 PSMA5 PSME3 PSME3 PSME1 PSME1 ENSSTOP00000025153 ENSSTOP00000025153 PSMD2 PSMD2 LOC101972090 LOC101972090 PSMD13 PSMD13 ENSSTOP00000024305 ENSSTOP00000024305 PSMB3 PSMB3 PSMF1 PSMF1 GSK3B GSK3B GLI3 GLI3 PSMD3 PSMD3 SUFU SUFU LOC101967492 LOC101967492 PSMA7 PSMA7 PSMC4 PSMC4 PSMD6 PSMD6 PSMD5 PSMD5 PSMD1 PSMD1 Rps27a Rps27a PSMB1 PSMB1 PSMC3 PSMC3 Psmc5 Psmc5 PSME4 PSME4 PSMB5 PSMB5 PSMA1 PSMA1 CUL1 CUL1 PSMC2 PSMC2 UBA52 UBA52 PSMD10 PSMD10 PSMB9 PSMB9 PRKACA PRKACA PSMB10 PSMB10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMB2Proteasome subunit beta. (201 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
Psmc626S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa)
Psmb6Proteasome subunit beta. (239 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
Rbx1RING-type domain-containing protein. (108 aa)
PSMA8Proteasome subunit alpha type. (257 aa)
PSMB11Proteasome subunit beta. (293 aa)
LOC101957545Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (328 aa)
I3N110_ICTTRRING-type domain-containing protein. (147 aa)
I3N1R8_ICTTRUncharacterized protein. (199 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
PSMB8Proteasome subunit beta. (276 aa)
Psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
CSNK1A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (353 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
ENSSTOP00000030001AAA domain-containing protein. (334 aa)
ENSSTOP00000029537Proteasome subunit beta. (200 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ENSSTOP00000031690ANK_REP_REGION domain-containing protein. (189 aa)
Psmd9PDZ domain-containing protein. (223 aa)
Psma6Proteasome subunit alpha type. (148 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
ENSSTOP00000028717RING-type domain-containing protein. (95 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
PSME2Proteasome activator subunit 2. (239 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSME3Proteasome activator subunit 3. (254 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ENSSTOP00000025153PROTEASOME_ALPHA_1 domain-containing protein. (87 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
LOC101972090AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
ENSSTOP00000024305Uncharacterized protein. (210 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
GLI3GLI family zinc finger 3. (1582 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (488 aa)
LOC101967492Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
PSMB1Proteasome subunit beta. (240 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
Psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
PSMB5Proteasome subunit beta. (220 aa)
PSMA1Proteasome subunit alpha type. (266 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PSMD10ANK_REP_REGION domain-containing protein. (226 aa)
PSMB9Proteasome subunit beta. (219 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (334 aa)
PSMB10Proteasome subunit beta. (273 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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