STRINGSTRING
ADCY5 ADCY5 GLIS3 GLIS3 PSMD4 PSMD4 PSMB2 PSMB2 PSMB10 PSMB10 PRKACA PRKACA ADCY4 ADCY4 Pdcd2l Pdcd2l ADCY10 ADCY10 OFD1 OFD1 PSMB9 PSMB9 IFT140 IFT140 PSMD10 PSMD10 PRKAR1B PRKAR1B ADCY6 ADCY6 IFT122 IFT122 TULP2 TULP2 GLI2 GLI2 UBA52 UBA52 ADCY2 ADCY2 FOPNL FOPNL ADCY9 ADCY9 PSMC2 PSMC2 TUB TUB CUL1 CUL1 PTRHD1 PTRHD1 ADCY3 ADCY3 PSMA1 PSMA1 WDR19 WDR19 PSMB5 PSMB5 WDR35 WDR35 TUBAL3 TUBAL3 PSME4 PSME4 ADCY1 ADCY1 Psmc5 Psmc5 PSMD1 PSMD1 Rps27a Rps27a MKS1 MKS1 IFT52 IFT52 KIF3A KIF3A PSMB1 PSMB1 TULP3 TULP3 PSMC3 PSMC3 LOC101968254 LOC101968254 Psmd9 Psmd9 SMO SMO TTC21A TTC21A Psma6 Psma6 PSMB4 PSMB4 PSMA7 PSMA7 PSMC4 PSMC4 PSMD6 PSMD6 PRKAR1A PRKAR1A PSMD5 PSMD5 PSMD7 PSMD7 PSMA2 PSMA2 PSMA3 PSMA3 IFT57 IFT57 PSMB7 PSMB7 I3MMQ2_ICTTR I3MMQ2_ICTTR PSMD8 PSMD8 Psmc6 Psmc6 ITCH ITCH Psmb6 Psmb6 PSMD14 PSMD14 CNBD2 CNBD2 TULP1 TULP1 IFT88 IFT88 Rbx1 Rbx1 PSMA8 PSMA8 PDCD2 PDCD2 GLIS1 GLIS1 TUBB1 TUBB1 PSMB11 PSMB11 TUBB4B TUBB4B LOC101957545 LOC101957545 Tubb3 Tubb3 KIF7 KIF7 I3N110_ICTTR I3N110_ICTTR I3N1R8_ICTTR I3N1R8_ICTTR LOC101973486 LOC101973486 TUBB2A TUBB2A LOC101966763 LOC101966763 Tuba1c Tuba1c GLI1 GLI1 NUMBL NUMBL PSMB8 PSMB8 TUBB6 TUBB6 RPGRIP1L RPGRIP1L LOC101974619 LOC101974619 BTRC BTRC TUBB4A TUBB4A LOC101967492 LOC101967492 TUBA1A TUBA1A LOC101961494 LOC101961494 SUFU SUFU TUBB2B TUBB2B LOC101970177 LOC101970177 PSMD3 PSMD3 GLI3 GLI3 GSK3B GSK3B PSMF1 PSMF1 GPR161 GPR161 TUBA4A TUBA4A PSMB3 PSMB3 ENSSTOP00000024305 ENSSTOP00000024305 TUBA3D TUBA3D TTC21B TTC21B PSMD13 PSMD13 LOC101972090 LOC101972090 PSMD2 PSMD2 ENSSTOP00000025153 ENSSTOP00000025153 LOC101955741 LOC101955741 PRKAR2A PRKAR2A PSME1 PSME1 PSME3 PSME3 PSMA5 PSMA5 PSMD11 PSMD11 PSME2 PSME2 ENSSTOP00000027359 ENSSTOP00000027359 IFT172 IFT172 DYNC2H1 DYNC2H1 TUBA1B TUBA1B ADCY7 ADCY7 ENSSTOP00000028703 ENSSTOP00000028703 ENSSTOP00000028717 ENSSTOP00000028717 PSMA4 PSMA4 INTU INTU PRKACB PRKACB ENSSTOP00000029537 ENSSTOP00000029537 TEX52 TEX52 THAP6 THAP6 ENSSTOP00000030001 ENSSTOP00000030001 SKP1 SKP1 ADCY8 ADCY8 CSNK1A1 CSNK1A1 PTCH1 PTCH1 Numb Numb ENSSTOP00000031366 ENSSTOP00000031366 FUZ FUZ PSMD12 PSMD12 Psmc1 Psmc1 ENSSTOP00000031690 ENSSTOP00000031690 PRKAR2B PRKAR2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
GLIS3GLIS family zinc finger 3. (931 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMB10Proteasome subunit beta. (273 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (334 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
Pdcd2lPDCD2_C domain-containing protein. (355 aa)
ADCY10Adenylate cyclase 10. (1610 aa)
OFD1OFD1 centriole and centriolar satellite protein. (1027 aa)
PSMB9Proteasome subunit beta. (219 aa)
IFT140Intraflagellar transport 140. (1459 aa)
PSMD10ANK_REP_REGION domain-containing protein. (226 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
IFT122Intraflagellar transport 122. (1118 aa)
TULP2Tubby-like protein; Belongs to the TUB family. (469 aa)
GLI2GLI family zinc finger 2. (1540 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (955 aa)
FOPNLFGFR1OP N-terminal like. (160 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
TUBTubby-like protein; Belongs to the TUB family. (506 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
PSMA1Proteasome subunit alpha type. (266 aa)
WDR19WD repeat domain 19. (1341 aa)
PSMB5Proteasome subunit beta. (220 aa)
WDR35WD repeat-containing protein 35; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking. (1181 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
Psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
IFT52Intraflagellar transport 52. (425 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (726 aa)
PSMB1Proteasome subunit beta. (240 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (464 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
LOC101968254Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
Psmd9PDZ domain-containing protein. (223 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
TTC21ATetratricopeptide repeat domain 21A. (1341 aa)
Psma6Proteasome subunit alpha type. (148 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
IFT57Intraflagellar transport 57. (429 aa)
PSMB7Proteasome subunit beta. (277 aa)
I3MMQ2_ICTTRUncharacterized protein. (384 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
Psmc626S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa)
ITCHE3 ubiquitin-protein ligase. (855 aa)
Psmb6Proteasome subunit beta. (239 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
CNBD2Cyclic nucleotide binding domain containing 2. (560 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (513 aa)
IFT88Intraflagellar transport 88. (825 aa)
Rbx1RING-type domain-containing protein. (108 aa)
PSMA8Proteasome subunit alpha type. (257 aa)
PDCD2Programmed cell death 2. (241 aa)
GLIS1GLIS family zinc finger 1. (790 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
PSMB11Proteasome subunit beta. (293 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
LOC101957545Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (328 aa)
Tubb3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
KIF7Kinesin family member 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1345 aa)
I3N110_ICTTRRING-type domain-containing protein. (147 aa)
I3N1R8_ICTTRUncharacterized protein. (199 aa)
LOC101973486Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
Tuba1cTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
GLI1GLI family zinc finger 1. (1107 aa)
NUMBLNUMB like endocytic adaptor protein. (522 aa)
PSMB8Proteasome subunit beta. (276 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (390 aa)
RPGRIP1LRPGRIP1 like. (1299 aa)
LOC101974619Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
LOC101967492Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
LOC101961494Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (488 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
LOC101970177Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
GLI3GLI family zinc finger 3. (1582 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
GPR161G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (529 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSSTOP00000024305Uncharacterized protein. (210 aa)
TUBA3DTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
TTC21BTetratricopeptide repeat domain 21B. (1316 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
LOC101972090AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
ENSSTOP00000025153PROTEASOME_ALPHA_1 domain-containing protein. (87 aa)
LOC101955741Guanylate cyclase domain-containing protein. (412 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (399 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSME3Proteasome activator subunit 3. (254 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSME2Proteasome activator subunit 2. (239 aa)
ENSSTOP00000027359PID domain-containing protein. (588 aa)
IFT172Intraflagellar transport 172. (1755 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4312 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (331 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
ENSSTOP00000028717RING-type domain-containing protein. (95 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
INTUInturned planar cell polarity protein. (942 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ENSSTOP00000029537Proteasome subunit beta. (200 aa)
TEX52Testis expressed 52. (302 aa)
THAP6THAP domain containing 6. (217 aa)
ENSSTOP00000030001AAA domain-containing protein. (334 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
CSNK1A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (353 aa)
PTCH1Patched 1. (1450 aa)
NumbPID domain-containing protein. (653 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
FUZFuzzy planar cell polarity protein. (358 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
Psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ENSSTOP00000031690ANK_REP_REGION domain-containing protein. (189 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (417 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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