20 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NFKB1	Nuclear factor kappa B subunit 1. (985 aa)
	EP300	E1A binding protein p300. (2423 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	ICAM2	Intercellular adhesion molecule 2. (278 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	PAK1	Non-specific serine/threonine protein kinase. (544 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	I3MW17_ICTTR	C-type lectin domain-containing protein. (242 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (551 aa)
	LOC101969495	C-type lectin domain-containing protein. (240 aa)
	CCDC71L	Uncharacterized protein. (176 aa)
	ERAS	ES cell expressed Ras. (227 aa)
	I3NEH4_ICTTR	C-type lectin domain-containing protein. (207 aa)
	PAK3	Non-specific serine/threonine protein kinase. (559 aa)
	RELB	RELB proto-oncogene, NF-kB subunit. (567 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	LOC101969219	C-type lectin domain-containing protein. (264 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	LOC101969790	C-type lectin domain-containing protein. (209 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EP300	NFKB1	ENSSTOP00000000650	ENSSTOP00000010277	E1A binding protein p300.	Nuclear factor kappa B subunit 1.	0.960
EP300	RELA	ENSSTOP00000000650	ENSSTOP00000017232	E1A binding protein p300.	RELA proto-oncogene, NF-kB subunit.	0.986
EP300	RELB	ENSSTOP00000000650	ENSSTOP00000026551	E1A binding protein p300.	RELB proto-oncogene, NF-kB subunit.	0.887
ERAS	FYN	ENSSTOP00000020926	ENSSTOP00000006598	ES cell expressed Ras.	Tyrosine-protein kinase.	0.607
ERAS	LYN	ENSSTOP00000020926	ENSSTOP00000029495	ES cell expressed Ras.	Tyrosine-protein kinase.	0.634
ERAS	NFKB1	ENSSTOP00000020926	ENSSTOP00000010277	ES cell expressed Ras.	Nuclear factor kappa B subunit 1.	0.447
ERAS	PAK1	ENSSTOP00000020926	ENSSTOP00000011468	ES cell expressed Ras.	Non-specific serine/threonine protein kinase.	0.595
ERAS	PAK2	ENSSTOP00000020926	ENSSTOP00000007400	ES cell expressed Ras.	Non-specific serine/threonine protein kinase.	0.602
ERAS	PAK3	ENSSTOP00000020926	ENSSTOP00000026466	ES cell expressed Ras.	Non-specific serine/threonine protein kinase.	0.595
ERAS	RELA	ENSSTOP00000020926	ENSSTOP00000017232	ES cell expressed Ras.	RELA proto-oncogene, NF-kB subunit.	0.442
ERAS	RELB	ENSSTOP00000020926	ENSSTOP00000026551	ES cell expressed Ras.	RELB proto-oncogene, NF-kB subunit.	0.430
FYN	ERAS	ENSSTOP00000006598	ENSSTOP00000020926	Tyrosine-protein kinase.	ES cell expressed Ras.	0.607
FYN	HRAS	ENSSTOP00000006598	ENSSTOP00000028539	Tyrosine-protein kinase.	HRas proto-oncogene, GTPase.	0.607
FYN	KRAS	ENSSTOP00000006598	ENSSTOP00000008545	Tyrosine-protein kinase.	KRAS proto-oncogene, GTPase.	0.607
FYN	LYN	ENSSTOP00000006598	ENSSTOP00000029495	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.958
FYN	NFKB1	ENSSTOP00000006598	ENSSTOP00000010277	Tyrosine-protein kinase.	Nuclear factor kappa B subunit 1.	0.409
FYN	NRAS	ENSSTOP00000006598	ENSSTOP00000015289	Tyrosine-protein kinase.	NRAS proto-oncogene, GTPase.	0.607
FYN	PAK1	ENSSTOP00000006598	ENSSTOP00000011468	Tyrosine-protein kinase.	Non-specific serine/threonine protein kinase.	0.565
FYN	PAK2	ENSSTOP00000006598	ENSSTOP00000007400	Tyrosine-protein kinase.	Non-specific serine/threonine protein kinase.	0.646
FYN	PAK3	ENSSTOP00000006598	ENSSTOP00000026466	Tyrosine-protein kinase.	Non-specific serine/threonine protein kinase.	0.565