Your Input: | |
| | MBD3 | Methyl-CpG binding domain protein 3. (292 aa) |
| | TXNDC11 | Thioredoxin domain containing 11. (882 aa) |
| | PRDM1 | PR/SET domain 1. (821 aa) |
| | Sgk1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (454 aa) |
| | ZNF385A | Zinc finger protein 385A. (385 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (1995 aa) |
| | TP53RK | TP53 regulating kinase. (246 aa) |
| | I3MUA8_ICTTR | AAA domain-containing protein. (312 aa) |
| | POU4F3 | POU domain protein. (338 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | I3MUQ5_ICTTR | RING-type domain-containing protein. (239 aa) |
| | BRD9 | Bromodomain containing 9. (557 aa) |
| | EHMT2 | Euchromatic histone lysine methyltransferase 2. (1254 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (592 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (281 aa) |
| | RMI1 | RecQ mediated genome instability 1. (625 aa) |
| | POU4F1 | POU domain protein. (294 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (982 aa) |
| | RFC2 | Replication factor C subunit 2. (321 aa) |
| | NUAK1 | NUAK family kinase 1. (629 aa) |
| | Ing1 | Inhibitor of growth protein. (233 aa) |
| | NUAK2 | NUAK family kinase 2. (631 aa) |
| | TAF2 | TATA-box binding protein associated factor 2. (1212 aa) |
| | LOC101966763 | Ubiquitin-like domain-containing protein. (156 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa) |
| | AIRE | Autoimmune regulator. (515 aa) |
| | ING5 | Inhibitor of growth family member 5. (250 aa) |
| | L3MBTL4 | L3MBTL histone methyl-lysine binding protein 4. (536 aa) |
| | LOC101971599 | Uncharacterized protein. (730 aa) |
| | PHF20 | PHD finger protein 20. (1013 aa) |
| | KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2017 aa) |
| | POU4F2 | POU domain protein. (410 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1208 aa) |
| | I3NC46_ICTTR | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (397 aa) |
| | MEIOB | Meiosis specific with OB-fold. (471 aa) |
| | ZNF385C | Zinc finger protein 385C. (418 aa) |
| | BRD7 | Bromodomain containing 7. (648 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (634 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (383 aa) |
| | GATAD2A | GATA zinc finger domain containing 2A. (653 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | Kmt5a | SET domain-containing protein. (486 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (561 aa) |
| | MEAF6 | MYST/Esa1 associated factor 6. (183 aa) |
| | Rfc5 | AAA domain-containing protein. (340 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa) |
| | ENSSTOP00000024463 | RING-type domain-containing protein. (209 aa) |
| | MAPKAPK5 | MAPK activated protein kinase 5. (472 aa) |
| | ENSSTOP00000026345 | Protein kinase domain-containing protein. (386 aa) |
| | RFFL | Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (396 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (658 aa) |
| | ENSSTOP00000026639 | Hist_deacetyl domain-containing protein. (323 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (542 aa) |
| | Ppp2cb | Serine/threonine-protein phosphatase. (274 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa) |
| | ENSSTOP00000027631 | SER_THR_PHOSPHATASE domain-containing protein. (235 aa) |
| | CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | ENSSTOP00000027930 | Uncharacterized protein. (173 aa) |
| | TOPBP1 | DNA topoisomerase II binding protein 1. (1527 aa) |
| | ENSSTOP00000028194 | SAE2 domain-containing protein. (75 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa) |
| | TAF15 | TATA-box binding protein associated factor 15. (584 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | BANP | BTG3 associated nuclear protein. (506 aa) |
| | ENSSTOP00000028703 | Ubiquitin-like domain-containing protein. (122 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | PIP4P2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (326 aa) |
| | ENSSTOP00000029771 | AAA domain-containing protein. (336 aa) |
| | LOC101973423 | ING domain-containing protein. (203 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (2030 aa) |
| | Ly6g5b | Uncharacterized protein. (195 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (277 aa) |
| | ENSSTOP00000030597 | Uncharacterized protein. (100 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1085 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | EHMT1 | Euchromatic histone lysine methyltransferase 1. (1270 aa) |
| | TAF13 | TATA-box binding protein associated factor 13. (124 aa) |
| | ENSSTOP00000031366 | Ubiquitin-like domain-containing protein. (95 aa) |
| | LOC101954817 | Inhibitor of growth protein 2 pseudogene. (174 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | Taf9 | Uncharacterized protein. (265 aa) |
| | Plk5 | Uncharacterized protein. (608 aa) |
| | ZNF385B | Zinc finger protein 385B. (486 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2577 aa) |
| | TAF4B | TATA-box binding protein associated factor 4b. (855 aa) |
| | RHNO1 | RAD9-HUS1-RAD1 interacting nuclear orphan 1. (240 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) |
| | BLM | BLM RecQ like helicase. (1414 aa) |
| | I3M4Y3_ICTTR | Protein kinase domain-containing protein. (142 aa) |
| | RAD17 | RAD17 checkpoint clamp loader component. (699 aa) |
| | I3M4T6_ICTTR | Uncharacterized protein. (243 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | ATM | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2618 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (239 aa) |
| | RPA2 | Replication protein A2. (271 aa) |
| | Mdm4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (421 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (343 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa) |
| | MTA2 | Metastasis associated 1 family member 2. (614 aa) |
| | RBBP7 | RB binding protein 7, chromatin remodeling factor. (425 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (437 aa) |
| | CHEK1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (432 aa) |
| | DAXX | Death domain associated protein. (740 aa) |
| | BARD1 | BRCA1 associated RING domain 1. (776 aa) |
| | BRPF1 | Bromodomain and PHD finger containing 1. (1248 aa) |
| | TAF9B | TATA-box binding protein associated factor 9b. (287 aa) |
| | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (406 aa) |
| | PPP1R13L | Protein phosphatase 1 regulatory subunit 13 like. (840 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) |
| | PIP4K2C | Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (420 aa) |
| | TAF3 | TATA-box binding protein associated factor 3. (930 aa) |
| | Taf7l | TAFII55_N domain-containing protein. (294 aa) |
| | EP300 | E1A binding protein p300. (2423 aa) |
| | Brca1 | Uncharacterized protein. (353 aa) |
| | RFC3 | Replication factor C subunit 3. (339 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (631 aa) |
| | TAF12 | TATA-box binding protein associated factor 12. (213 aa) |
| | CCNG1 | Cyclin G1; Belongs to the cyclin family. (295 aa) |
| | SMYD2 | SET and MYND domain containing 2. (429 aa) |
| | TBP | TATA-box binding protein. (323 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | Csnk2a1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (678 aa) |
| | BRD1 | Bromodomain containing 1. (1058 aa) |
| | TP53BP2 | Tumor protein p53 binding protein 2. (1134 aa) |
| | Rps27a | Ubiquitin-like domain-containing protein. (156 aa) |
| | RAD1 | RAD1 checkpoint DNA exonuclease. (279 aa) |
| | CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) |
| | HIPK3 | Homeodomain interacting protein kinase 3. (1214 aa) |
| | RNF34 | Ring finger protein 34. (385 aa) |
| | Rad50 | Zinc-hook domain-containing protein. (1312 aa) |
| | NOC2L | NOC2 like nucleolar associated transcriptional repressor. (667 aa) |
| | L3MBTL3 | L3MBTL histone methyl-lysine binding protein 3. (699 aa) |
| | TTC5 | Tetratricopeptide repeat domain 5. (440 aa) |
| | ATRIP | ATR interacting protein. (793 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1087 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (937 aa) |
| | MAPKAP1 | MAPK associated protein 1. (522 aa) |
| | CHEK2 | Checkpoint kinase 2. (545 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | L3mbtl1 | Uncharacterized protein. (829 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1060 aa) |
| | Rbbp8 | CtIP_N domain-containing protein. (773 aa) |
| | Aurka | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (363 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (403 aa) |
| | RBBP4 | RB binding protein 4, chromatin remodeling factor. (425 aa) |
| | TAF7 | TATA-box binding protein associated factor 7. (349 aa) |
| | Hdac1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (399 aa) |
| | Rfc4 | AAA domain-containing protein. (364 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (248 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (556 aa) |
| | Taf11 | TATA-box binding protein associated factor 11. (211 aa) |
| | PML | Promyelocytic leukemia. (877 aa) |
| | WRN | WRN RecQ like helicase. (1448 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1057 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa) |
| | Ing2 | Inhibitor of growth protein. (280 aa) |
| | FOXP4 | Forkhead box P4. (666 aa) |
| | TAF5 | TATA-box binding protein associated factor 5. (787 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa) |
| | Mdm2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (636 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (221 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1007 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (634 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (325 aa) |
| | Taf1 | Transcription initiation factor TFIID subunit. (1926 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (345 aa) |
| | GATAD2B | GATA zinc finger domain containing 2B. (592 aa) |
| | USP2 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (612 aa) |
| | HIPK4 | Homeodomain interacting protein kinase 4. (616 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1660 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1163 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (646 aa) |
| | DYRK4 | Dual specificity tyrosine phosphorylation regulated kinase 4. (637 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (490 aa) |
| | BRPF3 | Bromodomain and PHD finger containing 3. (1211 aa) |
| | TBPL1 | TATA-box binding protein like 1. (186 aa) |
| | SETD9 | SET domain containing 9. (299 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (304 aa) |
| | Chd4 | Uncharacterized protein. (1909 aa) |
| | TPX2 | TPX2 microtubule nucleation factor. (746 aa) |
| | DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (420 aa) |
