STRINGSTRING
MAPK1 MAPK1 FGF20 FGF20 FGF6 FGF6 MAPK3 MAPK3 PPP2R1A PPP2R1A LOC101973790 LOC101973790 BRAF BRAF FGFR2 FGFR2 UBA52 UBA52 CBL CBL FGF5 FGF5 FGF23 FGF23 Rps27a Rps27a PPP2CA PPP2CA FNDC3A FNDC3A MKNK2 MKNK2 GRB2 GRB2 FGF17 FGF17 FRS2 FRS2 FGF16 FGF16 FNDC3B FNDC3B Fgf2 Fgf2 FGF7 FGF7 Spry2 Spry2 LOC101976832 LOC101976832 FGF22 FGF22 Fgf4 Fgf4 FGF10 FGF10 LOC101958853 LOC101958853 LOC101966763 LOC101966763 PTPN11 PTPN11 FGF3 FGF3 FGF1 FGF1 FGF18 FGF18 FGF9 FGF9 ENSSTOP00000024013 ENSSTOP00000024013 FGF8 FGF8 Ppp2cb Ppp2cb ENSSTOP00000027631 ENSSTOP00000027631 ENSSTOP00000028703 ENSSTOP00000028703 ENSSTOP00000031366 ENSSTOP00000031366
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK1Mitogen-activated protein kinase. (331 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
MAPK3Mitogen-activated protein kinase. (361 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
LOC101973790Uncharacterized protein. (311 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (754 aa)
FGFR2Fibroblast growth factor receptor. (823 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
CBLCbl proto-oncogene. (870 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (271 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (252 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (461 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FNDC3BFibronectin type III domain containing 3B. (1208 aa)
Fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (144 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
Spry2Uncharacterized protein. (315 aa)
LOC101976832Uncharacterized protein. (1356 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (166 aa)
Fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC101958853Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSSTOP00000024013Uncharacterized protein. (102 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
Ppp2cbSerine/threonine-protein phosphatase. (274 aa)
ENSSTOP00000027631SER_THR_PHOSPHATASE domain-containing protein. (235 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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