STRINGSTRING
EDA2R EDA2R TNFRSF17 TNFRSF17 PSMC3 PSMC3 Psmd9 Psmd9 PSMD12 PSMD12 ENSSTOP00000031366 ENSSTOP00000031366 TNFSF12 TNFSF12 MAP3K14 MAP3K14 TNFRSF9 TNFRSF9 SKP1 SKP1 ENSSTOP00000030003 ENSSTOP00000030003 ENSSTOP00000030001 ENSSTOP00000030001 BIRC7 BIRC7 ENSSTOP00000029537 ENSSTOP00000029537 Tnfrsf13c Tnfrsf13c PSMA4 PSMA4 ENSSTOP00000028703 ENSSTOP00000028703 TNFRSF12A TNFRSF12A PSME2 PSME2 PSMD11 PSMD11 TNFSF13 TNFSF13 PSMA5 PSMA5 TRAF5 TRAF5 RELB RELB PSME3 PSME3 PSME1 PSME1 ENSSTOP00000025153 ENSSTOP00000025153 PSMD2 PSMD2 LOC101972090 LOC101972090 PSMD13 PSMD13 ENSSTOP00000024305 ENSSTOP00000024305 PSMB3 PSMB3 LTB LTB PSMF1 PSMF1 PSMD3 PSMD3 CD40 CD40 FBXW11 FBXW11 UBE2M UBE2M LOC101967492 LOC101967492 TNFSF13B TNFSF13B BTRC BTRC Cd70 Cd70 PSMB8 PSMB8 LOC101966763 LOC101966763 EDARADD EDARADD TNFRSF11A TNFRSF11A I3N1R8_ICTTR I3N1R8_ICTTR EDAR EDAR TNFSF14 TNFSF14 Tnfrsf13b Tnfrsf13b TNFRSF25 TNFRSF25 PSMB11 PSMB11 TNFSF15 TNFSF15 Naip Naip TNFRSF1B TNFRSF1B CHUK CHUK TNFSF8 TNFSF8 PSMA8 PSMA8 PSMD14 PSMD14 Psmb6 Psmb6 Psmc6 Psmc6 PSMD8 PSMD8 PSMB7 PSMB7 PSMA3 PSMA3 PSMA2 PSMA2 LTBR LTBR PSMD7 PSMD7 PSMD5 PSMD5 TNF TNF LTA LTA PSMD6 PSMD6 PSMC4 PSMC4 PSMA7 PSMA7 TRAF2 TRAF2 PSMB4 PSMB4 Psma6 Psma6 UBA3 UBA3 NFKB2 NFKB2 PSMB10 PSMB10 PSMB2 PSMB2 EDA EDA TRAF3 TRAF3 PSMD4 PSMD4 Psmc1 Psmc1 ENSSTOP00000031690 ENSSTOP00000031690 TNFSF18 TNFSF18 TNFSF11 TNFSF11 TNFRSF1A TNFRSF1A Rps27a Rps27a TNFRSF11B TNFRSF11B PSMD1 PSMD1 Psmc5 Psmc5 PSME4 PSME4 PSMB1 PSMB1 CD27 CD27 PSMB5 PSMB5 PSMA1 PSMA1 CD40LG CD40LG CUL1 CUL1 Birc2 Birc2 BIRC3 BIRC3 PSMC2 PSMC2 UBA52 UBA52 PSMD10 PSMD10 XIAP XIAP PSMB9 PSMB9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDA2REctodysplasin A2 receptor. (297 aa)
TNFRSF17TNF receptor superfamily member 17. (182 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
Psmd9PDZ domain-containing protein. (223 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
TNFSF12TNF superfamily member 12; Belongs to the tumor necrosis factor family. (249 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (934 aa)
TNFRSF9TNF receptor superfamily member 9. (238 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
ENSSTOP00000030003Uncharacterized protein. (546 aa)
ENSSTOP00000030001AAA domain-containing protein. (334 aa)
BIRC7Baculoviral IAP repeat containing 7. (304 aa)
ENSSTOP00000029537Proteasome subunit beta. (200 aa)
Tnfrsf13cUncharacterized protein. (104 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
TNFRSF12ATNF receptor superfamily member 12A. (129 aa)
PSME2Proteasome activator subunit 2. (239 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
TNFSF13TNF superfamily member 13; Belongs to the tumor necrosis factor family. (250 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
RELBRELB proto-oncogene, NF-kB subunit. (567 aa)
PSME3Proteasome activator subunit 3. (254 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ENSSTOP00000025153PROTEASOME_ALPHA_1 domain-containing protein. (87 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
LOC101972090AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
ENSSTOP00000024305Uncharacterized protein. (210 aa)
PSMB3Proteasome subunit beta. (205 aa)
LTBLymphotoxin beta; Belongs to the tumor necrosis factor family. (320 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
CD40CD40 molecule. (284 aa)
FBXW11F-box and WD repeat domain containing 11. (553 aa)
UBE2MUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
LOC101967492Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (280 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
Cd70TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (177 aa)
PSMB8Proteasome subunit beta. (276 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
EDARADDEDAR associated death domain. (205 aa)
TNFRSF11ATNF receptor superfamily member 11a. (625 aa)
I3N1R8_ICTTRUncharacterized protein. (199 aa)
EDAREctodysplasin A receptor. (448 aa)
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (237 aa)
Tnfrsf13bUncharacterized protein. (120 aa)
TNFRSF25TNF receptor superfamily member 25. (431 aa)
PSMB11Proteasome subunit beta. (293 aa)
TNFSF15TNF superfamily member 15. (257 aa)
NaipNACHT domain-containing protein. (1405 aa)
TNFRSF1BTNF receptor superfamily member 1B. (436 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (769 aa)
TNFSF8TNF superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa)
PSMA8Proteasome subunit alpha type. (257 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
Psmb6Proteasome subunit beta. (239 aa)
Psmc626S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
LTBRLymphotoxin beta receptor. (435 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
LTALymphotoxin alpha; Belongs to the tumor necrosis factor family. (205 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Psma6Proteasome subunit alpha type. (148 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (450 aa)
NFKB2Nuclear factor kappa B subunit 2. (899 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB2Proteasome subunit beta. (201 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (391 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (566 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
Psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ENSSTOP00000031690ANK_REP_REGION domain-containing protein. (189 aa)
TNFSF18TNF superfamily member 18. (172 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa)
TNFRSF1ATNF receptor superfamily member 1A. (437 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
TNFRSF11BTumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
Psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
PSMB1Proteasome subunit beta. (240 aa)
CD27CD27 molecule. (239 aa)
PSMB5Proteasome subunit beta. (220 aa)
PSMA1Proteasome subunit alpha type. (266 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (259 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
Birc2Uncharacterized protein. (611 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PSMD10ANK_REP_REGION domain-containing protein. (226 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
PSMB9Proteasome subunit beta. (219 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.