STRINGSTRING
CASP10 CASP10 RIPK1 RIPK1 RIPK3 RIPK3 FLOT2 FLOT2 PDCD6IP PDCD6IP XIAP XIAP UBA52 UBA52 BIRC3 BIRC3 Birc2 Birc2 TNFSF10 TNFSF10 Faslg Faslg SDCBP SDCBP Rps27a Rps27a CASP8 CASP8 TRADD TRADD OGT OGT TRAF2 TRAF2 CDC37 CDC37 Ube2l3 Ube2l3 Naip Naip STUB1 STUB1 PELI1 PELI1 LOC101959922 LOC101959922 PRKN PRKN LOC101966763 LOC101966763 FLOT1 FLOT1 FADD FADD CFLAR CFLAR MLKL MLKL ENSSTOP00000028703 ENSSTOP00000028703 BIRC7 BIRC7 ENSSTOP00000030003 ENSSTOP00000030003 ENSSTOP00000031366 ENSSTOP00000031366
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CASP10Caspase 10; Belongs to the peptidase C14A family. (480 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (665 aa)
RIPK3Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (491 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
PDCD6IPProgrammed cell death 6 interacting protein. (875 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
Birc2Uncharacterized protein. (611 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (296 aa)
FaslgTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (69 aa)
SDCBPSyndecan binding protein. (298 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (520 aa)
TRADDTNFRSF1A associated via death domain. (302 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
CDC37Cell division cycle 37. (378 aa)
Ube2l3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
NaipNACHT domain-containing protein. (1405 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
LOC101959922Uncharacterized protein. (442 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (463 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (488 aa)
MLKLMixed lineage kinase domain like pseudokinase. (472 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
BIRC7Baculoviral IAP repeat containing 7. (304 aa)
ENSSTOP00000030003Uncharacterized protein. (546 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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