STRINGSTRING
LOC101972090 LOC101972090 PSMD2 PSMD2 RSPH4A RSPH4A PRKACB PRKACB ENSSTOP00000025153 ENSSTOP00000025153 PSMA4 PSMA4 Septin7 Septin7 PSME1 PSME1 ETV1 ETV1 PSME3 PSME3 ENSSTOP00000026289 ENSSTOP00000026289 PAK3 PAK3 LOC101974667 LOC101974667 PSMA5 PSMA5 PSMD11 PSMD11 PSME2 PSME2 CDK1 CDK1 ENSSTOP00000028703 ENSSTOP00000028703 PSMB10 PSMB10 PSMB2 PSMB2 RSPH6A RSPH6A Cdc42 Cdc42 PSMD4 PSMD4 RAG1 RAG1 DNAJB1 DNAJB1 BRSK2 BRSK2 PSMB11 PSMB11 Mov10 Mov10 PSMA8 PSMA8 DNAJB5 DNAJB5 PSMD14 PSMD14 Psmb6 Psmb6 Psmc6 Psmc6 PSMD8 PSMD8 DNAJB4 DNAJB4 PSMB7 PSMB7 PSMA3 PSMA3 CDC42EP3 CDC42EP3 PSMA2 PSMA2 PSMD7 PSMD7 PSMD5 PSMD5 PAK1 PAK1 PSMD6 PSMD6 PSMC4 PSMC4 PSMA7 PSMA7 PSMB4 PSMB4 Psma6 Psma6 Psmd9 Psmd9 CDKN3 CDKN3 PSMC3 PSMC3 IGF2BP1 IGF2BP1 PSMB1 PSMB1 Foxo1 Foxo1 Rps27a Rps27a PSMD1 PSMD1 Psmc5 Psmc5 PSME4 PSME4 PAK2 PAK2 PSMB5 PSMB5 RAC1 RAC1 PSMA1 PSMA1 BRSK1 BRSK1 DNAJB13 DNAJB13 ENSSTOP00000031690 ENSSTOP00000031690 Psmc1 Psmc1 PSMD12 PSMD12 LOC101966144 LOC101966144 ENSSTOP00000031366 ENSSTOP00000031366 NCOA3 NCOA3 ENSSTOP00000030001 ENSSTOP00000030001 ENSSTOP00000029537 ENSSTOP00000029537 KALRN KALRN PSMC2 PSMC2 UBA52 UBA52 PSMD10 PSMD10 PSMB9 PSMB9 PRKACA PRKACA Dusp23 Dusp23 CDC14B CDC14B MAPK4 MAPK4 CDC14A CDC14A I3N1R8_ICTTR I3N1R8_ICTTR HSPB1 HSPB1 I3N4S4_ICTTR I3N4S4_ICTTR LOC101966763 LOC101966763 PSMB8 PSMB8 RAG2 RAG2 Cdc42ep5 Cdc42ep5 Foxo3 Foxo3 PSMD3 PSMD3 PSMF1 PSMF1 CCND3 CCND3 ENSSTOP00000024231 ENSSTOP00000024231 PSMB3 PSMB3 ENSSTOP00000024305 ENSSTOP00000024305 XPO1 XPO1 ENSSTOP00000024629 ENSSTOP00000024629 MAPKAPK5 MAPKAPK5 PSMD13 PSMD13 ETV4 ETV4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101972090AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
RSPH4ARadial spoke head component 4A. (512 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ENSSTOP00000025153PROTEASOME_ALPHA_1 domain-containing protein. (87 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
Septin7Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (438 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ETV1ETS variant 1. (476 aa)
PSME3Proteasome activator subunit 3. (254 aa)
ENSSTOP00000026289Uncharacterized protein. (885 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
LOC101974667Protein kinase domain-containing protein. (692 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSME2Proteasome activator subunit 2. (239 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB2Proteasome subunit beta. (201 aa)
RSPH6ARadial spoke head 6 homolog A. (722 aa)
Cdc42Uncharacterized protein. (191 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (340 aa)
BRSK2BR serine/threonine kinase 2. (701 aa)
PSMB11Proteasome subunit beta. (293 aa)
Mov10AAA_12 domain-containing protein. (1054 aa)
PSMA8Proteasome subunit alpha type. (257 aa)
DNAJB5DnaJ heat shock protein family (Hsp40) member B5. (348 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
Psmb6Proteasome subunit beta. (239 aa)
Psmc626S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
DNAJB4DnaJ heat shock protein family (Hsp40) member B4. (337 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CDC42EP3CDC42 effector protein 3. (254 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Psma6Proteasome subunit alpha type. (148 aa)
Psmd9PDZ domain-containing protein. (223 aa)
CDKN3Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (211 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
IGF2BP1Insulin like growth factor 2 mRNA binding protein 1. (577 aa)
PSMB1Proteasome subunit beta. (240 aa)
Foxo1Forkhead box protein O1; Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalc [...] (535 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
Psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
PSMB5Proteasome subunit beta. (220 aa)
RAC1Rac family small GTPase 1. (211 aa)
PSMA1Proteasome subunit alpha type. (266 aa)
BRSK1BR serine/threonine kinase 1. (772 aa)
DNAJB13DnaJ heat shock protein family (Hsp40) member B13. (316 aa)
ENSSTOP00000031690ANK_REP_REGION domain-containing protein. (189 aa)
Psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
LOC101966144Uncharacterized protein. (147 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
NCOA3Nuclear receptor coactivator. (1413 aa)
ENSSTOP00000030001AAA domain-containing protein. (334 aa)
ENSSTOP00000029537Proteasome subunit beta. (200 aa)
KALRNKalirin RhoGEF kinase. (2951 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PSMD10ANK_REP_REGION domain-containing protein. (226 aa)
PSMB9Proteasome subunit beta. (219 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (334 aa)
Dusp23TYR_PHOSPHATASE_2 domain-containing protein. (122 aa)
CDC14BUncharacterized protein. (450 aa)
MAPK4Mitogen-activated protein kinase 4. (581 aa)
CDC14ACell division cycle 14A. (612 aa)
I3N1R8_ICTTRUncharacterized protein. (199 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (202 aa)
I3N4S4_ICTTRUncharacterized protein. (162 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
PSMB8Proteasome subunit beta. (276 aa)
RAG2Recombination activating 2. (526 aa)
Cdc42ep5CRIB domain-containing protein. (79 aa)
Foxo3Forkhead box O3. (673 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
ENSSTOP00000024231Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (276 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSSTOP00000024305Uncharacterized protein. (210 aa)
XPO1Exportin 1. (1071 aa)
ENSSTOP00000024629Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (352 aa)
MAPKAPK5MAPK activated protein kinase 5. (472 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
ETV4ETS variant 4. (486 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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