STRINGSTRING
RUVBL1 RUVBL1 Hif1a Hif1a MYC MYC IFIH1 IFIH1 PSMC2 PSMC2 USP2 USP2 USP20 USP20 USP24 USP24 I3M6L1_ICTTR I3M6L1_ICTTR BIRC3 BIRC3 Birc2 Birc2 POLB POLB VDAC3 VDAC3 USP8 USP8 IDE IDE DMWD DMWD PSMA1 PSMA1 USP21 USP21 USP14 USP14 WDR20 WDR20 TOMM70 TOMM70 WDR76 WDR76 USP16 USP16 DDX58 DDX58 PSMB5 PSMB5 SNX3 SNX3 TRAF6 TRAF6 DDB2 DDB2 NFKBIA NFKBIA VDAC1 VDAC1 CCNA2 CCNA2 PSME4 PSME4 CCP110 CCP110 Psmc5 Psmc5 Map3k20 Map3k20 PSMD1 PSMD1 UBA52 UBA52 Mdm4 Mdm4 USP47 USP47 SMAD2 SMAD2 PSMD10 PSMD10 CCNA1 CCNA1 PSMB9 PSMB9 UFD1 UFD1 NFATC4 NFATC4 SKP2 SKP2 ADRM1 ADRM1 USP13 USP13 TNKS2 TNKS2 TAB1 TAB1 TADA3 TADA3 PSMB10 PSMB10 USP19 USP19 PSMB2 PSMB2 RIPK1 RIPK1 GATA3 GATA3 LAP3 LAP3 UBLCP1 UBLCP1 USP9X USP9X PSMD4 PSMD4 USP50 USP50 HGS HGS Mat2b Mat2b Rps27a Rps27a CDC20 CDC20 KEAP1 KEAP1 CYLD CYLD SMAD3 SMAD3 USP48 USP48 PSMB1 PSMB1 SMAD1 SMAD1 RNF13 RNF13 PSMC3 PSMC3 ZFYVE1 ZFYVE1 USP4 USP4 USP12 USP12 Psmd9 Psmd9 Arr3 Arr3 TAF10 TAF10 Psma6 Psma6 PSMB4 PSMB4 TRAF2 TRAF2 NPEPL1 NPEPL1 AXIN1 AXIN1 PSMA7 PSMA7 PSMC4 PSMC4 Atxn7 Atxn7 PSMD6 PSMD6 LOC101970492 LOC101970492 PSMD5 PSMD5 PSMD7 PSMD7 PSMA2 PSMA2 PSMA3 PSMA3 TGFBR1 TGFBR1 PSMB7 PSMB7 FKBP8 FKBP8 USP33 USP33 KLHL17 KLHL17 PSMD8 PSMD8 Psmc6 Psmc6 TNKS TNKS Mdm2 Mdm2 Psmb6 Psmb6 PSMD14 PSMD14 USP10 USP10 USP5 USP5 PSMA8 PSMA8 Usp36 Usp36 USP51 USP51 Naip Naip AR AR I3MU26_ICTTR I3MU26_ICTTR PTEN PTEN PSMB11 PSMB11 SMAD7 SMAD7 SUDS3 SUDS3 KLHL18 KLHL18 ADRB2 ADRB2 I3MUQ5_ICTTR I3MUQ5_ICTTR STAM2 STAM2 ZNRF4 ZNRF4 LOC101962637 LOC101962637 USP30 USP30 USP34 USP34 TRRAP TRRAP SMAD4 SMAD4 RNF167 RNF167 WDR48 WDR48 OTUB1 OTUB1 USP44 USP44 LOC101964833 LOC101964833 USP27X USP27X USP49 USP49 RCE1 RCE1 MTFP1 MTFP1 Usp32 Usp32 UBFD1 UBFD1 I3N1R8_ICTTR I3N1R8_ICTTR Usp26 Usp26 Tomm20 Tomm20 LOC101960833 LOC101960833 LOC101966763 LOC101966763 TP53 TP53 PSMB8 PSMB8 USP11 USP11 USP22 USP22 AXIN2 AXIN2 RNF123 RNF123 I3N8V5_ICTTR I3N8V5_ICTTR BECN2 BECN2 CLSPN CLSPN FOXO4 FOXO4 PTRH2 PTRH2 PSMD3 PSMD3 RNF128 RNF128 PSMF1 PSMF1 Usp18 Usp18 LOC101970445 LOC101970445 LOC101972712 LOC101972712 ARRB2 ARRB2 ENSSTOP00000024214 ENSSTOP00000024214 ARRB1 ARRB1 PSMB3 PSMB3 ENSSTOP00000024305 ENSSTOP00000024305 MUL1 MUL1 ENSSTOP00000024463 ENSSTOP00000024463 USP3 USP3 PSMD13 PSMD13 LOC101972090 LOC101972090 Becn1 Becn1 PSMD2 PSMD2 ENSSTOP00000025153 ENSSTOP00000025153 CDC20B CDC20B ENSSTOP00000025343 ENSSTOP00000025343 IL33 IL33 SMURF2 SMURF2 NRDC NRDC ATXN7L1 ATXN7L1 PSME1 PSME1 PSME3 PSME3 USP28 USP28 Zfyve19 Zfyve19 USP42 USP42 GPR21 GPR21 PSMA5 PSMA5 PSMD11 PSMD11 SIAH2 SIAH2 IKBKG IKBKG PSME2 PSME2 SNX12 SNX12 ENSSTOP00000028703 ENSSTOP00000028703 PSMA4 PSMA4 USP37 USP37 ATXN7L2 ATXN7L2 VDAC2 VDAC2 ENSSTOP00000029537 ENSSTOP00000029537 BIRC7 BIRC7 ENSSTOP00000030001 ENSSTOP00000030001 ENSSTOP00000030003 ENSSTOP00000030003 ENSSTOP00000030245 ENSSTOP00000030245 USP7 USP7 USP15 USP15 ENSSTOP00000031178 ENSSTOP00000031178 RNF146 RNF146 ENSSTOP00000031366 ENSSTOP00000031366 USP25 USP25 PSMD12 PSMD12 KAT2A KAT2A Psmc1 Psmc1 ENSSTOP00000031690 ENSSTOP00000031690 USP46 USP46 MAP3K7 MAP3K7
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (384 aa)
Hif1aUncharacterized protein. (821 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa)
IFIH1Interferon induced with helicase C domain 1. (974 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (612 aa)
USP20Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (782 aa)
USP24Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family. (2550 aa)
I3M6L1_ICTTRABC transmembrane type-1 domain-containing protein. (528 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
Birc2Uncharacterized protein. (611 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (306 aa)
VDAC3Voltage dependent anion channel 3. (284 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1097 aa)
IDEInsulin degrading enzyme; Belongs to the peptidase M16 family. (1019 aa)
DMWDDM1 locus, WD repeat containing. (685 aa)
PSMA1Proteasome subunit alpha type. (266 aa)
USP21Ubiquitin specific peptidase 21; Belongs to the peptidase C19 family. (567 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (500 aa)
WDR20WD repeat domain 20. (581 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (609 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (623 aa)
USP16Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. (825 aa)
DDX58DExD/H-box helicase 58. (925 aa)
PSMB5Proteasome subunit beta. (220 aa)
SNX3Sorting nexin 3. (162 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa)
DDB2Damage specific DNA binding protein 2. (430 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
VDAC1Voltage dependent anion channel 1. (292 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (420 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
CCP110Centriolar coiled-coil protein 110. (1012 aa)
Psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
Map3k20Uncharacterized protein. (800 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
Mdm4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
PSMD10ANK_REP_REGION domain-containing protein. (226 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
PSMB9Proteasome subunit beta. (219 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (307 aa)
NFATC4Nuclear factor of activated T cells 4. (890 aa)
SKP2S-phase kinase associated protein 2. (401 aa)
ADRM1Adhesion regulating molecule 1. (407 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
TNKS2Poly [ADP-ribose] polymerase. (1155 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa)
TADA3Transcriptional adaptor 3. (351 aa)
PSMB10Proteasome subunit beta. (273 aa)
USP19Ubiquitin specific peptidase 19. (1358 aa)
PSMB2Proteasome subunit beta. (201 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (665 aa)
GATA3GATA binding protein 3. (444 aa)
LAP3Leucine aminopeptidase 3. (519 aa)
UBLCP1Ubiquitin like domain containing CTD phosphatase 1. (310 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2554 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
USP50Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (377 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (776 aa)
Mat2bMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (334 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
CDC20Cell division cycle 20. (499 aa)
KEAP1Kelch like ECH associated protein 1. (624 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
USP48Ubiquitin specific peptidase 48; Belongs to the peptidase C19 family. (1036 aa)
PSMB1Proteasome subunit beta. (240 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
RNF13Ring finger protein 13. (381 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (777 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (963 aa)
USP12Ubiquitin specific peptidase 12; Belongs to the peptidase C19 family. (370 aa)
Psmd9PDZ domain-containing protein. (223 aa)
Arr3Arrestin-C; May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins (By similarity). (393 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
Psma6Proteasome subunit alpha type. (148 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
NPEPL1Aminopeptidase like 1. (473 aa)
AXIN1Axin 1. (869 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
Atxn7SCA7 domain-containing protein. (842 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
LOC101970492Histone H2A; Belongs to the histone H2A family. (131 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (489 aa)
PSMB7Proteasome subunit beta. (277 aa)
FKBP8Peptidylprolyl isomerase. (374 aa)
USP33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (911 aa)
KLHL17Kelch like family member 17. (641 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
Psmc626S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
Mdm2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa)
Psmb6Proteasome subunit beta. (239 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (788 aa)
USP5Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (858 aa)
PSMA8Proteasome subunit alpha type. (257 aa)
Usp36Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1106 aa)
USP51Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (703 aa)
NaipNACHT domain-containing protein. (1405 aa)
ARAndrogen receptor. (884 aa)
I3MU26_ICTTRUncharacterized protein. (145 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
PSMB11Proteasome subunit beta. (293 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
SUDS3SDS3 homolog, SIN3A corepressor complex component. (328 aa)
KLHL18Kelch like family member 18. (579 aa)
ADRB2Adrenoceptor beta 2. (416 aa)
I3MUQ5_ICTTRRING-type domain-containing protein. (239 aa)
STAM2Signal transducing adaptor molecule 2. (524 aa)
ZNRF4Zinc and ring finger 4. (312 aa)
LOC101962637Ubiquitin_3 domain-containing protein. (348 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (489 aa)
USP34Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3548 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3861 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
RNF167Ring finger protein 167. (345 aa)
WDR48WD repeat domain 48. (677 aa)
OTUB1Ubiquitin thioesterase. (271 aa)
USP44Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (710 aa)
LOC101964833CheR domain-containing protein. (301 aa)
USP27XUbiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (438 aa)
USP49Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (685 aa)
RCE1Ras converting CAAX endopeptidase 1. (329 aa)
MTFP1Mitochondrial fission process 1. (166 aa)
Usp32Uncharacterized protein; Belongs to the peptidase C19 family. (1604 aa)
UBFD1Ubiquitin family domain containing 1. (301 aa)
I3N1R8_ICTTRUncharacterized protein. (199 aa)
Usp26Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (922 aa)
Tomm20Uncharacterized protein. (145 aa)
LOC101960833Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (527 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa)
PSMB8Proteasome subunit beta. (276 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (917 aa)
USP22Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (525 aa)
AXIN2Axin 2. (840 aa)
RNF123Ring finger protein 123. (1314 aa)
I3N8V5_ICTTRSANT domain-containing protein. (330 aa)
BECN2Beclin 2. (412 aa)
CLSPNClaspin. (1320 aa)
FOXO4Forkhead box O4. (505 aa)
PTRH2Peptidyl-tRNA hydrolase 2. (179 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
RNF128Ring finger protein 128. (428 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
Usp18USP domain-containing protein; Belongs to the peptidase C19 family. (354 aa)
LOC101970445Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (527 aa)
LOC101972712Histone H2B type 1. (126 aa)
ARRB2Arrestin beta 2. (409 aa)
ENSSTOP00000024214Uncharacterized protein. (151 aa)
ARRB1Arrestin beta 1. (418 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSSTOP00000024305Uncharacterized protein. (210 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
ENSSTOP00000024463RING-type domain-containing protein. (209 aa)
USP3Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (520 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
LOC101972090AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
Becn1Beclin 1. (448 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
ENSSTOP00000025153PROTEASOME_ALPHA_1 domain-containing protein. (87 aa)
CDC20BCell division cycle 20B. (523 aa)
ENSSTOP00000025343Uncharacterized protein. (310 aa)
IL33Interleukin 33. (264 aa)
SMURF2E3 ubiquitin-protein ligase. (740 aa)
NRDCNardilysin convertase. (1231 aa)
ATXN7L1Ataxin 7 like 1. (868 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSME3Proteasome activator subunit 3. (254 aa)
USP28Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1144 aa)
Zfyve19Uncharacterized protein. (280 aa)
USP42Ubiquitin specific peptidase 42; Belongs to the peptidase C19 family. (1331 aa)
GPR21G protein-coupled receptor 21; Belongs to the G-protein coupled receptor 1 family. (348 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (318 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (492 aa)
PSME2Proteasome activator subunit 2. (239 aa)
SNX12Sorting nexin 12. (163 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
USP37Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (976 aa)
ATXN7L2Ataxin 7 like 2. (696 aa)
VDAC2Voltage dependent anion channel 2. (294 aa)
ENSSTOP00000029537Proteasome subunit beta. (200 aa)
BIRC7Baculoviral IAP repeat containing 7. (304 aa)
ENSSTOP00000030001AAA domain-containing protein. (334 aa)
ENSSTOP00000030003Uncharacterized protein. (546 aa)
ENSSTOP00000030245Uncharacterized protein. (174 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1085 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
ENSSTOP00000031178Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (320 aa)
RNF146Ring finger protein 146. (354 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
USP25Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (864 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
Psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ENSSTOP00000031690ANK_REP_REGION domain-containing protein. (189 aa)
USP46Ubiquitin specific peptidase 46; Belongs to the peptidase C19 family. (366 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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