STRINGSTRING
POLE POLE I3MUA8_ICTTR I3MUA8_ICTTR I3MU87_ICTTR I3MU87_ICTTR ATAD5 ATAD5 Pold4 Pold4 Rbx1 Rbx1 Polr2c Polr2c RCBTB2 RCBTB2 ERCC4 ERCC4 Rfc4 Rfc4 POLD1 POLD1 ERCC3 ERCC3 Rps27a Rps27a POLR2I POLR2I POLR2H POLR2H DDB1 DDB1 RFC1 RFC1 POLE2 POLE2 LOC101968680 LOC101968680 Bivm Bivm GTF2H3 GTF2H3 POLR2K POLR2K ZNF830 ZNF830 UVSSA UVSSA ERCC8 ERCC8 UBA52 UBA52 RPA2 RPA2 POLR2G POLR2G CUL4A CUL4A MEIOB MEIOB Pcna Pcna LOC101956825 LOC101956825 POLR2F POLR2F I3NCX7_ICTTR I3NCX7_ICTTR I3NC22_ICTTR I3NC22_ICTTR TCEA1 TCEA1 MNAT1 MNAT1 I3NBH0_ICTTR I3NBH0_ICTTR LOC101956464 LOC101956464 Pole3 Pole3 POLR2D POLR2D LOC101966763 LOC101966763 TCEA3 TCEA3 I3N4G2_ICTTR I3N4G2_ICTTR I3N110_ICTTR I3N110_ICTTR USP40 USP40 RFC2 RFC2 CDK7 CDK7 Gtf2h2c Gtf2h2c GTF2H4 GTF2H4 Rfc5 Rfc5 ENSSTOP00000025372 ENSSTOP00000025372 LOC101973038 LOC101973038 POLE4 POLE4 AQR AQR RCBTB1 RCBTB1 RPA3 RPA3 ERCC2 ERCC2 ENSSTOP00000027307 ENSSTOP00000027307 Hmgn1 Hmgn1 Polk Polk ENSSTOP00000028703 ENSSTOP00000028703 POLR2B POLR2B PHF3 PHF3 LOC101962734 LOC101962734 CUL4B CUL4B Polr2l Polr2l RPA1 RPA1 ENSSTOP00000028717 ENSSTOP00000028717 Upk3bl2 Upk3bl2 PPIE PPIE ENSSTOP00000029771 ENSSTOP00000029771 TCEA2 TCEA2 XAB2 XAB2 USP7 USP7 ENSSTOP00000030987 ENSSTOP00000030987 Polr2a Polr2a ENSSTOP00000031366 ENSSTOP00000031366 PRPF19 PRPF19 ENSSTOP00000031583 ENSSTOP00000031583 LOC101975289 LOC101975289 Polr2j Polr2j GTF2H5 GTF2H5 ERCC6 ERCC6 POLR2E POLR2E ERCC1 ERCC1 XPA XPA POLD2 POLD2 TCEANC2 TCEANC2 Spocd1 Spocd1 NRDE2 NRDE2 EP300 EP300 CCNH CCNH Pold3 Pold3 GTF2H1 GTF2H1 RFC3 RFC3 TCEANC TCEANC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2282 aa)
I3MUA8_ICTTRAAA domain-containing protein. (312 aa)
I3MU87_ICTTRProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (250 aa)
ATAD5ATPase family AAA domain containing 5. (1897 aa)
Pold4Uncharacterized protein. (107 aa)
Rbx1RING-type domain-containing protein. (108 aa)
Polr2cRPOLD domain-containing protein. (406 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (551 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
Rfc4AAA domain-containing protein. (364 aa)
POLD1DNA polymerase. (1106 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
RFC1Replication factor C subunit 1. (1118 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (504 aa)
LOC101968680ERCC excision repair 5, endonuclease. (1170 aa)
BivmUncharacterized protein. (503 aa)
GTF2H3General transcription factor IIH subunit 3. (309 aa)
POLR2KUncharacterized protein. (58 aa)
ZNF830Zinc finger protein 830. (370 aa)
UVSSAUV stimulated scaffold protein A. (743 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
RPA2Replication protein A2. (271 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
CUL4ACullin 4A; Belongs to the cullin family. (671 aa)
MEIOBMeiosis specific with OB-fold. (471 aa)
PcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
LOC101956825Non-histone chromosomal protein HMG-17. (90 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
I3NCX7_ICTTRUncharacterized protein. (90 aa)
I3NC22_ICTTRUncharacterized protein. (90 aa)
TCEA1Transcription elongation factor A1. (323 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
I3NBH0_ICTTRUncharacterized protein. (90 aa)
LOC101956464Uncharacterized protein. (90 aa)
Pole3CBFD_NFYB_HMF domain-containing protein. (147 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
TCEA3Transcription elongation factor A3. (352 aa)
I3N4G2_ICTTRUncharacterized protein. (90 aa)
I3N110_ICTTRRING-type domain-containing protein. (147 aa)
USP40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1234 aa)
RFC2Replication factor C subunit 2. (321 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
Gtf2h2cGeneral transcription factor IIH subunit. (395 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
Rfc5AAA domain-containing protein. (340 aa)
ENSSTOP00000025372CBFD_NFYB_HMF domain-containing protein. (134 aa)
LOC101973038UmuC domain-containing protein. (265 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (115 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1484 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
RPA3Replication protein A3. (121 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
ENSSTOP00000027307TFIIS N-terminal domain-containing protein. (73 aa)
Hmgn1Uncharacterized protein. (74 aa)
PolkUmuC domain-containing protein. (541 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
PHF3PHD finger protein 3. (2015 aa)
LOC101962734Uncharacterized protein. (285 aa)
CUL4BCullin 4B; Belongs to the cullin family. (970 aa)
Polr2lUncharacterized protein. (83 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (592 aa)
ENSSTOP00000028717RING-type domain-containing protein. (95 aa)
Upk3bl2Uncharacterized protein. (276 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
ENSSTOP00000029771AAA domain-containing protein. (336 aa)
TCEA2Transcription elongation factor A2. (300 aa)
XAB2XPA binding protein 2. (881 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1085 aa)
ENSSTOP00000030987Uncharacterized protein. (49 aa)
Polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
PRPF19Pre-mRNA processing factor 19. (512 aa)
ENSSTOP00000031583annotation not available (85 aa)
LOC101975289RPOLD domain-containing protein. (254 aa)
Polr2jRNA polymerase II subunit J. (117 aa)
GTF2H5General transcription factor IIH subunit 5. (74 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1521 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa)
XPAXPA, DNA damage recognition and repair factor. (275 aa)
POLD2DNA polymerase delta 2, accessory subunit. (469 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain containing 2. (208 aa)
Spocd1TFIIS central domain-containing protein. (586 aa)
NRDE2NRDE-2, necessary for RNA interference, domain containing. (1165 aa)
EP300E1A binding protein p300. (2423 aa)
CCNHCyclin H; Belongs to the cyclin family. (323 aa)
Pold3Uncharacterized protein. (467 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
RFC3Replication factor C subunit 3. (339 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (352 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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