STRINGSTRING
IL12A IL12A LOC106144935 LOC106144935 IL17F IL17F CXCL8 CXCL8 TYK2 TYK2 HSP90B1 HSP90B1 BCL6B BCL6B IL10 IL10 JAK2 JAK2 STAT3 STAT3 JAK3 JAK3 IL13 IL13 IL17A IL17A STAT1 STAT1 IRF4 IRF4 FOXS1 FOXS1 STAT6 STAT6 PIM2 PIM2 GLMP GLMP IL13RA2 IL13RA2 ZEB1 ZEB1 IL18 IL18 MCL1 MCL1 LAMA5 LAMA5 Nanog Nanog BATF BATF CDKN1A CDKN1A JAK1 JAK1 PIM1 PIM1 SOCS1 SOCS1 SOCS5 SOCS5 FSCN1 FSCN1 LOC101969207 LOC101969207 IL4R IL4R Dusp15 Dusp15 LOC101970926 LOC101970926 IL13RA1 IL13RA1 BCL6 BCL6 JUNB JUNB ZEB2 ZEB2 FCER2 FCER2 Il2rg Il2rg
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
LOC106144935Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (100 aa)
IL17FInterleukin 17F. (161 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
TYK2Tyrosine-protein kinase. (1194 aa)
HSP90B1Heat shock protein 90 beta family member 1. (805 aa)
BCL6BBCL6B transcription repressor. (474 aa)
IL10Interleukin 10. (178 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
STAT3Signal transducer and activator of transcription. (748 aa)
JAK3Tyrosine-protein kinase. (1042 aa)
IL13Interleukin 13. (130 aa)
IL17AInterleukin 17A. (154 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
IRF4Interferon regulatory factor 4. (451 aa)
FOXS1Forkhead box S1. (333 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (370 aa)
GLMPGlycosylated lysosomal membrane protein. (420 aa)
IL13RA2Interleukin 13 receptor subunit alpha 2. (388 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1123 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (333 aa)
LAMA5Laminin subunit alpha 5. (3474 aa)
NanogHomeobox domain-containing protein. (306 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (162 aa)
JAK1Tyrosine-protein kinase. (1142 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
SOCS1Suppressor of cytokine signaling 1. (211 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
FSCN1Fascin. (493 aa)
LOC101969207C-C motif chemokine. (136 aa)
IL4RInterleukin 4 receptor. (795 aa)
Dusp15IRF tryptophan pentad repeat domain-containing protein. (433 aa)
LOC101970926Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (424 aa)
BCL6BCL6 transcription repressor. (706 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1249 aa)
FCER2Fc fragment of IgE receptor II. (319 aa)
Il2rgFibronectin type-III domain-containing protein. (374 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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