STRINGSTRING
RAD9B RAD9B RHNO1 RHNO1 TAF4B TAF4B Plk5 Plk5 Taf9 Taf9 CDK5 CDK5 ENSSTOP00000031366 ENSSTOP00000031366 TAF13 TAF13 PRKAB2 PRKAB2 ENSSTOP00000030597 ENSSTOP00000030597 Ly6g5b Ly6g5b ENSSTOP00000029771 ENSSTOP00000029771 KAT5 KAT5 CDK2 CDK2 ENSSTOP00000028703 ENSSTOP00000028703 TAF15 TAF15 ENSSTOP00000028194 ENSSTOP00000028194 TOPBP1 TOPBP1 ENSSTOP00000027930 ENSSTOP00000027930 SSRP1 SSRP1 PRKAG2 PRKAG2 RPA3 RPA3 ENSSTOP00000026345 ENSSTOP00000026345 MAPKAPK5 MAPKAPK5 ENSSTOP00000024463 ENSSTOP00000024463 MRE11 MRE11 Rfc5 Rfc5 PRKAA1 PRKAA1 MAPK14 MAPK14 RAD9A RAD9A MEIOB MEIOB HIPK1 HIPK1 LOC101971599 LOC101971599 TP53 TP53 LOC101966763 LOC101966763 TAF2 TAF2 NUAK2 NUAK2 NUAK1 NUAK1 RFC2 RFC2 RMI1 RMI1 HUS1 HUS1 RPA1 RPA1 I3MUQ5_ICTTR I3MUQ5_ICTTR ATR ATR I3MUA8_ICTTR I3MUA8_ICTTR TP53RK TP53RK Taf1 Taf1 MAPK11 MAPK11 NBN NBN TOP3A TOP3A TP53INP2 TP53INP2 TAF4 TAF4 Mdm2 Mdm2 PRKAG1 PRKAG1 TAF5 TAF5 SLF1 SLF1 WRN WRN Taf11 Taf11 CSNK2B CSNK2B Rfc4 Rfc4 TAF7 TAF7 Aurka Aurka Rbbp8 Rbbp8 DNA2 DNA2 TAF10 TAF10 CHEK2 CHEK2 BRIP1 BRIP1 PRKAA2 PRKAA2 ATRIP ATRIP NOC2L NOC2L Rad50 Rad50 HIPK3 HIPK3 CDK5R1 CDK5R1 RAD1 RAD1 Rps27a Rps27a TAF6 TAF6 Csnk2a1 Csnk2a1 PRKAB1 PRKAB1 TBP TBP CCNA2 CCNA2 DYRK2 DYRK2 TPX2 TPX2 CDK3 CDK3 TBPL1 TBPL1 PRKAG3 PRKAG3 DYRK4 DYRK4 PLK3 PLK3 DYRK3 DYRK3 HIPK2 HIPK2 HIPK4 HIPK4 AURKB AURKB PIN1 PIN1 BLM BLM I3M4Y3_ICTTR I3M4Y3_ICTTR RAD17 RAD17 I3M4T6_ICTTR I3M4T6_ICTTR UBA52 UBA52 ATM ATM TP53INP1 TP53INP1 RPA2 RPA2 Mdm4 Mdm4 CCNA1 CCNA1 CSNK2A2 CSNK2A2 STK11 STK11 CHEK1 CHEK1 BARD1 BARD1 TAF9B TAF9B SUPT16H SUPT16H TAF3 TAF3 Taf7l Taf7l Brca1 Brca1 RFC3 RFC3 EXD2 EXD2 TAF12 TAF12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (403 aa)
RHNO1RAD9-HUS1-RAD1 interacting nuclear orphan 1. (240 aa)
TAF4BTATA-box binding protein associated factor 4b. (855 aa)
Plk5Uncharacterized protein. (608 aa)
Taf9Uncharacterized protein. (265 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
TAF13TATA-box binding protein associated factor 13. (124 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
ENSSTOP00000030597Uncharacterized protein. (100 aa)
Ly6g5bUncharacterized protein. (195 aa)
ENSSTOP00000029771AAA domain-containing protein. (336 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
TAF15TATA-box binding protein associated factor 15. (584 aa)
ENSSTOP00000028194SAE2 domain-containing protein. (75 aa)
TOPBP1DNA topoisomerase II binding protein 1. (1527 aa)
ENSSTOP00000027930Uncharacterized protein. (173 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (542 aa)
RPA3Replication protein A3. (121 aa)
ENSSTOP00000026345Protein kinase domain-containing protein. (386 aa)
MAPKAPK5MAPK activated protein kinase 5. (472 aa)
ENSSTOP00000024463RING-type domain-containing protein. (209 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa)
Rfc5AAA domain-containing protein. (340 aa)
PRKAA1Non-specific serine/threonine protein kinase. (561 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (383 aa)
MEIOBMeiosis specific with OB-fold. (471 aa)
HIPK1Homeodomain interacting protein kinase 1. (1208 aa)
LOC101971599Uncharacterized protein. (730 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
TAF2TATA-box binding protein associated factor 2. (1212 aa)
NUAK2NUAK family kinase 2. (631 aa)
NUAK1NUAK family kinase 1. (629 aa)
RFC2Replication factor C subunit 2. (321 aa)
RMI1RecQ mediated genome instability 1. (625 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (281 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (592 aa)
I3MUQ5_ICTTRRING-type domain-containing protein. (239 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
I3MUA8_ICTTRAAA domain-containing protein. (312 aa)
TP53RKTP53 regulating kinase. (246 aa)
Taf1Transcription initiation factor TFIID subunit. (1926 aa)
MAPK11Mitogen-activated protein kinase. (325 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (634 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1007 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (221 aa)
TAF4TATA-box binding protein associated factor 4. (636 aa)
Mdm2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa)
TAF5TATA-box binding protein associated factor 5. (787 aa)
SLF1SMC5-SMC6 complex localization factor 1. (1057 aa)
WRNWRN RecQ like helicase. (1448 aa)
Taf11TATA-box binding protein associated factor 11. (211 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (248 aa)
Rfc4AAA domain-containing protein. (364 aa)
TAF7TATA-box binding protein associated factor 7. (349 aa)
AurkaProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (363 aa)
Rbbp8CtIP_N domain-containing protein. (773 aa)
DNA2DNA replication helicase/nuclease 2. (1060 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
CHEK2Checkpoint kinase 2. (545 aa)
BRIP1BRCA1 interacting protein C-terminal helicase 1. (937 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
ATRIPATR interacting protein. (793 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (667 aa)
Rad50Zinc-hook domain-containing protein. (1312 aa)
HIPK3Homeodomain interacting protein kinase 3. (1214 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
RAD1RAD1 checkpoint DNA exonuclease. (279 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
TAF6TATA-box binding protein associated factor 6. (678 aa)
Csnk2a1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
TBPTATA-box binding protein. (323 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (420 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa)
TPX2TPX2 microtubule nucleation factor. (746 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (304 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (490 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (637 aa)
PLK3Serine/threonine-protein kinase PLK. (646 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa)
HIPK2Homeodomain interacting protein kinase 2. (1163 aa)
HIPK4Homeodomain interacting protein kinase 4. (616 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (345 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
BLMBLM RecQ like helicase. (1414 aa)
I3M4Y3_ICTTRProtein kinase domain-containing protein. (142 aa)
RAD17RAD17 checkpoint clamp loader component. (699 aa)
I3M4T6_ICTTRUncharacterized protein. (243 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ATMATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2618 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (239 aa)
RPA2Replication protein A2. (271 aa)
Mdm4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (343 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (437 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (432 aa)
BARD1BRCA1 associated RING domain 1. (776 aa)
TAF9BTATA-box binding protein associated factor 9b. (287 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
TAF3TATA-box binding protein associated factor 3. (930 aa)
Taf7lTAFII55_N domain-containing protein. (294 aa)
Brca1Uncharacterized protein. (353 aa)
RFC3Replication factor C subunit 3. (339 aa)
EXD2Exonuclease 3'-5' domain containing 2. (631 aa)
TAF12TATA-box binding protein associated factor 12. (213 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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