STRINGSTRING
LOC101966763 LOC101966763 Rps27a Rps27a L3MBTL3 L3MBTL3 TTC5 TTC5 PRMT5 PRMT5 CHEK2 CHEK2 L3mbtl1 L3mbtl1 Mdm2 Mdm2 I3MUQ5_ICTTR I3MUQ5_ICTTR EHMT2 EHMT2 JMY JMY TP53 TP53 L3MBTL4 L3MBTL4 Kmt5a Kmt5a ENSSTOP00000024463 ENSSTOP00000024463 ENSSTOP00000028703 ENSSTOP00000028703 EHMT1 EHMT1 ENSSTOP00000031366 ENSSTOP00000031366 SMYD2 SMYD2 SETD9 SETD9 UBA52 UBA52 ATM ATM Mdm4 Mdm4 EP300 EP300
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (699 aa)
TTC5Tetratricopeptide repeat domain 5. (440 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa)
CHEK2Checkpoint kinase 2. (545 aa)
L3mbtl1Uncharacterized protein. (829 aa)
Mdm2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa)
I3MUQ5_ICTTRRING-type domain-containing protein. (239 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1254 aa)
JMYJunction mediating and regulatory protein, p53 cofactor. (982 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa)
L3MBTL4L3MBTL histone methyl-lysine binding protein 4. (536 aa)
Kmt5aSET domain-containing protein. (486 aa)
ENSSTOP00000024463RING-type domain-containing protein. (209 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
EHMT1Euchromatic histone lysine methyltransferase 1. (1270 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
SMYD2SET and MYND domain containing 2. (429 aa)
SETD9SET domain containing 9. (299 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ATMATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2618 aa)
Mdm4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa)
EP300E1A binding protein p300. (2423 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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