STRINGSTRING
PSMD4 PSMD4 LOC101955676 LOC101955676 PSMB2 PSMB2 PSMB10 PSMB10 TNKS2 TNKS2 USP13 USP13 RBBP7 RBBP7 MTA2 MTA2 AKT2 AKT2 GUF1 GUF1 LAMTOR5 LAMTOR5 PSMB9 PSMB9 XIAP XIAP CSNK2A2 CSNK2A2 PSMD10 PSMD10 EZH1 EZH1 RHEBL1 RHEBL1 CRYGN CRYGN RHEB RHEB RRAGB RRAGB UBA52 UBA52 EED EED PSMC2 PSMC2 GATAD2B GATAD2B PHC2 PHC2 SNAI1 SNAI1 MKRN3 MKRN3 PSMA1 PSMA1 Rnf2 Rnf2 TRIM7 TRIM7 PSMB5 PSMB5 RRAGD RRAGD Chd4 Chd4 MTA1 MTA1 PSME4 PSME4 Csnk2a1 Csnk2a1 Psmc5 Psmc5 PSMD1 PSMD1 Rps27a Rps27a FRK FRK MKRN2 MKRN2 PSMB1 PSMB1 AKT3 AKT3 LAMTOR3 LAMTOR3 PSMC3 PSMC3 RRAGC RRAGC Psmd9 Psmd9 Psma6 Psma6 RBBP4 RBBP4 PSMB4 PSMB4 Hdac1 Hdac1 PSMA7 PSMA7 PSMC4 PSMC4 PSMD6 PSMD6 HDAC2 HDAC2 CSNK2B CSNK2B PSMD5 PSMD5 PSMD7 PSMD7 PSMA2 PSMA2 PSMA3 PSMA3 PML PML PSMB7 PSMB7 PSMD8 PSMD8 Psmc6 Psmc6 TNKS TNKS CBX8 CBX8 Psmb6 Psmb6 PSMD14 PSMD14 PSMA8 PSMA8 MBD3 MBD3 Mov10 Mov10 TXNDC11 TXNDC11 LAMTOR4 LAMTOR4 RING1 RING1 STUB1 STUB1 CHD3 CHD3 PTEN PTEN PSMB11 PSMB11 CBX2 CBX2 EGR1 EGR1 SCML2 SCML2 I3N1R8_ICTTR I3N1R8_ICTTR OTUD3 OTUD3 CBX6 CBX6 ATN1 ATN1 Rnf141 Rnf141 NPTX1 NPTX1 KIAA1671 KIAA1671 SLC38A9 SLC38A9 I3N4J8_ICTTR I3N4J8_ICTTR SALL4 SALL4 LOC101966763 LOC101966763 PSMB8 PSMB8 AIRE AIRE SNAI2 SNAI2 LAMTOR2 LAMTOR2 SNAI3 SNAI3 CBX4 CBX4 LAMTOR1 LAMTOR1 I3NC50_ICTTR I3NC50_ICTTR GATAD2A GATAD2A PSMD3 PSMD3 PSMF1 PSMF1 I3NG54_ICTTR I3NG54_ICTTR TRIM27 TRIM27 PSMB3 PSMB3 ENSSTOP00000024305 ENSSTOP00000024305 PSMD13 PSMD13 PHC3 PHC3 LOC101972090 LOC101972090 PSMD2 PSMD2 ENSSTOP00000025153 ENSSTOP00000025153 NEDD4 NEDD4 OTUD4 OTUD4 PSME1 PSME1 PSME3 PSME3 SALL2 SALL2 ENSSTOP00000026289 ENSSTOP00000026289 ENSSTOP00000026639 ENSSTOP00000026639 ENSSTOP00000026833 ENSSTOP00000026833 PSMA5 PSMA5 PSMD11 PSMD11 PSME2 PSME2 PHC1 PHC1 RERE RERE SUZ12 SUZ12 NPTXR NPTXR WWP2 WWP2 CRYBB3 CRYBB3 MAF1 MAF1 AKT1 AKT1 ENSSTOP00000028703 ENSSTOP00000028703 PSMA4 PSMA4 Mkrn1 Mkrn1 ENSSTOP00000028844 ENSSTOP00000028844 NPTX2 NPTX2 CBX7 CBX7 EZH2 EZH2 ENSSTOP00000029537 ENSSTOP00000029537 MLST8 MLST8 CHD5 CHD5 ENSSTOP00000030001 ENSSTOP00000030001 Ly6g5b Ly6g5b USP7 USP7 SCMH1 SCMH1 MTA3 MTA3 RPTOR RPTOR RNF146 RNF146 ENSSTOP00000031366 ENSSTOP00000031366 PSMD12 PSMD12 Psmc1 Psmc1 ENSSTOP00000031690 ENSSTOP00000031690 MECOM MECOM MTOR MTOR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
LOC101955676RING-type domain-containing protein. (326 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMB10Proteasome subunit beta. (273 aa)
TNKS2Poly [ADP-ribose] polymerase. (1155 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (425 aa)
MTA2Metastasis associated 1 family member 2. (614 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
GUF1Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (649 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa)
PSMB9Proteasome subunit beta. (219 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (343 aa)
PSMD10ANK_REP_REGION domain-containing protein. (226 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (747 aa)
RHEBL1RHEB like 1. (183 aa)
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (147 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
RRAGBRas related GTP binding B. (374 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
EEDEmbryonic ectoderm development. (441 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
GATAD2BGATA zinc finger domain containing 2B. (592 aa)
PHC2Polyhomeotic homolog 2. (855 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
MKRN3Makorin ring finger protein 3. (512 aa)
PSMA1Proteasome subunit alpha type. (266 aa)
Rnf2RING-type domain-containing protein. (336 aa)
TRIM7Tripartite motif containing 7. (510 aa)
PSMB5Proteasome subunit beta. (220 aa)
RRAGDRas related GTP binding D. (399 aa)
Chd4Uncharacterized protein. (1909 aa)
MTA1Metastasis associated 1. (689 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
Csnk2a1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
Psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
FRKTyrosine-protein kinase. (511 aa)
MKRN2Makorin ring finger protein 2. (415 aa)
PSMB1Proteasome subunit beta. (240 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
RRAGCRas related GTP binding C. (320 aa)
Psmd9PDZ domain-containing protein. (223 aa)
Psma6Proteasome subunit alpha type. (148 aa)
RBBP4RB binding protein 4, chromatin remodeling factor. (425 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Hdac1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (399 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (248 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PMLPromyelocytic leukemia. (877 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
Psmc626S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
CBX8Chromobox 8. (374 aa)
Psmb6Proteasome subunit beta. (239 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMA8Proteasome subunit alpha type. (257 aa)
MBD3Methyl-CpG binding domain protein 3. (292 aa)
Mov10AAA_12 domain-containing protein. (1054 aa)
TXNDC11Thioredoxin domain containing 11. (882 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (99 aa)
RING1Ring finger protein 1. (406 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
CHD3Chromodomain helicase DNA binding protein 3. (1995 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
PSMB11Proteasome subunit beta. (293 aa)
CBX2Chromobox 2. (491 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
SCML2Scm polycomb group protein like 2. (719 aa)
I3N1R8_ICTTRUncharacterized protein. (199 aa)
OTUD3OTU deubiquitinase 3. (324 aa)
CBX6Chromobox 6. (413 aa)
ATN1Atrophin 1. (1191 aa)
Rnf141RING-type domain-containing protein. (230 aa)
NPTX1Neuronal pentraxin 1. (432 aa)
KIAA1671KIAA1671. (1773 aa)
SLC38A9Solute carrier family 38 member 9. (561 aa)
I3N4J8_ICTTRUncharacterized protein. (126 aa)
SALL4Spalt like transcription factor 4. (610 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
PSMB8Proteasome subunit beta. (276 aa)
AIREAutoimmune regulator. (515 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
SNAI3Snail family transcriptional repressor 3. (291 aa)
CBX4Chromobox 4. (555 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
I3NC50_ICTTRUncharacterized protein. (112 aa)
GATAD2AGATA zinc finger domain containing 2A. (653 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
I3NG54_ICTTRUncharacterized protein. (91 aa)
TRIM27Tripartite motif containing 27. (513 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSSTOP00000024305Uncharacterized protein. (210 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
PHC3Polyhomeotic homolog 3. (983 aa)
LOC101972090AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
ENSSTOP00000025153PROTEASOME_ALPHA_1 domain-containing protein. (87 aa)
NEDD4E3 ubiquitin-protein ligase. (901 aa)
OTUD4OTU deubiquitinase 4. (1047 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSME3Proteasome activator subunit 3. (254 aa)
SALL2Spalt like transcription factor 2. (1013 aa)
ENSSTOP00000026289Uncharacterized protein. (885 aa)
ENSSTOP00000026639Hist_deacetyl domain-containing protein. (323 aa)
ENSSTOP00000026833RING-type domain-containing protein. (180 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSME2Proteasome activator subunit 2. (239 aa)
PHC1Polyhomeotic homolog 1. (1013 aa)
REREArginine-glutamic acid dipeptide repeats. (1553 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
NPTXRNeuronal pentraxin receptor. (471 aa)
WWP2E3 ubiquitin-protein ligase. (820 aa)
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (211 aa)
MAF1MAF1 homolog, negative regulator of RNA polymerase III. (347 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
Mkrn1Uncharacterized protein. (218 aa)
ENSSTOP00000028844Uncharacterized protein. (273 aa)
NPTX2Neuronal pentraxin 2. (423 aa)
CBX7Chromobox 7. (250 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (757 aa)
ENSSTOP00000029537Proteasome subunit beta. (200 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
CHD5Chromodomain helicase DNA binding protein 5. (2030 aa)
ENSSTOP00000030001AAA domain-containing protein. (334 aa)
Ly6g5bUncharacterized protein. (195 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1085 aa)
SCMH1Scm polycomb group protein homolog 1. (665 aa)
MTA3Metastasis associated 1 family member 3. (601 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
RNF146Ring finger protein 146. (354 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
Psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ENSSTOP00000031690ANK_REP_REGION domain-containing protein. (189 aa)
MECOMMDS1 and EVI1 complex locus. (1051 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2577 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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