STRINGSTRING
KPNB1 KPNB1 CDC27 CDC27 ANAPC10 ANAPC10 CDC23 CDC23 UBE2D1 UBE2D1 PSMB5 PSMB5 PSMA1 PSMA1 GMNN GMNN PSMC2 PSMC2 CDC6 CDC6 UBA52 UBA52 ORC3 ORC3 ANAPC1 ANAPC1 ORC5 ORC5 ORC6 ORC6 PSMD10 PSMD10 PSMB9 PSMB9 UBE2E1 UBE2E1 PSMB10 PSMB10 PSMB2 PSMB2 MCM3 MCM3 ANAPC16 ANAPC16 PSMD4 PSMD4 CDC26 CDC26 ANAPC2 ANAPC2 ENSSTOP00000031690 ENSSTOP00000031690 Psmc1 Psmc1 PSMD12 PSMD12 ENSSTOP00000031366 ENSSTOP00000031366 ENSSTOP00000030603 ENSSTOP00000030603 ENSSTOP00000030001 ENSSTOP00000030001 ENSSTOP00000029537 ENSSTOP00000029537 Mcm8 Mcm8 PSMA4 PSMA4 ENSSTOP00000028703 ENSSTOP00000028703 FZR1 FZR1 CDC16 CDC16 UBE2S UBE2S PSME2 PSME2 PSMD11 PSMD11 PSMA5 PSMA5 PSME3 PSME3 PSME1 PSME1 ENSSTOP00000025153 ENSSTOP00000025153 PSMD2 PSMD2 LOC101972090 LOC101972090 PSMD13 PSMD13 ENSSTOP00000024305 ENSSTOP00000024305 PSMB3 PSMB3 LOC101972712 LOC101972712 ANAPC15 ANAPC15 PSMF1 PSMF1 PSMD3 PSMD3 Tm4sf19 Tm4sf19 TM7SF3 TM7SF3 KPNA1 KPNA1 PSMB8 PSMB8 LOC101966763 LOC101966763 ORC4 ORC4 I3N1R8_ICTTR I3N1R8_ICTTR LOC101957469 LOC101957469 LOC101957760 LOC101957760 ORC2 ORC2 MCM2 MCM2 Anapc11 Anapc11 CDT1 CDT1 ANAPC4 ANAPC4 ORC1 ORC1 PSMD14 PSMD14 Psmb6 Psmb6 Psmc6 Psmc6 PSMD8 PSMD8 PSMB7 PSMB7 MCM6 MCM6 MCM5 MCM5 PSMA3 PSMA3 PSMA2 PSMA2 PSMD7 PSMD7 PSMD5 PSMD5 PSMD6 PSMD6 PSMC4 PSMC4 PSMA7 PSMA7 PSMB4 PSMB4 KPNA6 KPNA6 UBE2C UBE2C ANAPC7 ANAPC7 Psma6 Psma6 Psmd9 Psmd9 PSMC3 PSMC3 PSMB1 PSMB1 MCM4 MCM4 ANAPC5 ANAPC5 Rps27a Rps27a PSMD1 PSMD1 MCM7 MCM7 Psmc5 Psmc5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KPNB1Karyopherin subunit beta 1. (877 aa)
CDC27Cell division cycle 27. (848 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
CDC23Cell division cycle 23. (599 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
PSMB5Proteasome subunit beta. (220 aa)
PSMA1Proteasome subunit alpha type. (266 aa)
GMNNGeminin DNA replication inhibitor. (209 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (561 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ORC3Origin recognition complex subunit 3. (715 aa)
ANAPC1Anaphase promoting complex subunit 1. (1891 aa)
ORC5Origin recognition complex subunit 5. (435 aa)
ORC6Origin recognition complex subunit 6. (253 aa)
PSMD10ANK_REP_REGION domain-containing protein. (226 aa)
PSMB9Proteasome subunit beta. (219 aa)
UBE2E1UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB2Proteasome subunit beta. (201 aa)
MCM3DNA helicase; Belongs to the MCM family. (807 aa)
ANAPC16Anaphase promoting complex subunit 16. (122 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
CDC26Cell division cycle 26. (85 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (830 aa)
ENSSTOP00000031690ANK_REP_REGION domain-containing protein. (189 aa)
Psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
ENSSTOP00000030603UBIQUITIN_CONJUGAT_2 domain-containing protein. (183 aa)
ENSSTOP00000030001AAA domain-containing protein. (334 aa)
ENSSTOP00000029537Proteasome subunit beta. (200 aa)
Mcm8MCM domain-containing protein; Belongs to the MCM family. (833 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
CDC16Cell division cycle 16. (614 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa)
PSME2Proteasome activator subunit 2. (239 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSME3Proteasome activator subunit 3. (254 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ENSSTOP00000025153PROTEASOME_ALPHA_1 domain-containing protein. (87 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
LOC101972090AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
ENSSTOP00000024305Uncharacterized protein. (210 aa)
PSMB3Proteasome subunit beta. (205 aa)
LOC101972712Histone H2B type 1. (126 aa)
ANAPC15Anaphase promoting complex subunit 15. (151 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
Tm4sf19Uncharacterized protein. (210 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
PSMB8Proteasome subunit beta. (276 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
I3N1R8_ICTTRUncharacterized protein. (199 aa)
LOC101957469Histone H2B type 1-K. (126 aa)
LOC101957760Histone H2B; Belongs to the histone H2B family. (126 aa)
ORC2Origin recognition complex subunit 2. (578 aa)
MCM2DNA helicase; Belongs to the MCM family. (724 aa)
Anapc11RING-type domain-containing protein. (84 aa)
CDT1Chromatin licensing and DNA replication factor 1. (473 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (862 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
Psmb6Proteasome subunit beta. (239 aa)
Psmc626S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
PSMB7Proteasome subunit beta. (277 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
KPNA6Importin subunit alpha; Functions in nuclear protein import. (536 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
ANAPC7Anaphase promoting complex subunit 7. (581 aa)
Psma6Proteasome subunit alpha type. (148 aa)
Psmd9PDZ domain-containing protein. (223 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
PSMB1Proteasome subunit beta. (240 aa)
MCM4DNA helicase; Belongs to the MCM family. (862 aa)
ANAPC5Anaphase promoting complex subunit 5. (691 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
Psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (26%) [HD]