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| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | RFC3 | Replication factor C subunit 3. (339 aa) |
| | Pold3 | Uncharacterized protein. (467 aa) |
| | CDC26 | Cell division cycle 26. (85 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (378 aa) |
| | ANAPC16 | Anaphase promoting complex subunit 16. (122 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (807 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | POLD2 | DNA polymerase delta 2, accessory subunit. (469 aa) |
| | SKP2 | S-phase kinase associated protein 2. (401 aa) |
| | CDC45 | Cell division cycle 45. (567 aa) |
| | UBE2E1 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (421 aa) |
| | Pola2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) |
| | PSMD10 | ANK_REP_REGION domain-containing protein. (226 aa) |
| | ORC6 | Origin recognition complex subunit 6. (253 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1891 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | RPA2 | Replication protein A2. (271 aa) |
| | ORC3 | Origin recognition complex subunit 3. (715 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (561 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa) |
| | GMNN | Geminin DNA replication inhibitor. (209 aa) |
| | GINS3 | GINS complex subunit 3. (216 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | PSMA1 | Proteasome subunit alpha type. (266 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (504 aa) |
| | RFC1 | Replication factor C subunit 1. (1118 aa) |
| | PSMB5 | Proteasome subunit beta. (220 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (304 aa) |
| | CDC23 | Cell division cycle 23. (599 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | CDC27 | Cell division cycle 27. (848 aa) |
| | KPNB1 | Karyopherin subunit beta 1. (877 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (420 aa) |
| | PSME4 | Proteasome activator subunit 4. (1840 aa) |
| | Psmc5 | AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | Prim1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (407 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | Rps27a | Ubiquitin-like domain-containing protein. (156 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | ANAPC5 | Anaphase promoting complex subunit 5. (691 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (862 aa) |
| | PSMB1 | Proteasome subunit beta. (240 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa) |
| | LOC101956153 | Mcm10 domain-containing protein. (737 aa) |
| | Psmd9 | PDZ domain-containing protein. (223 aa) |
| | POLD1 | DNA polymerase. (1106 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1060 aa) |
| | Psma6 | Proteasome subunit alpha type. (148 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (581 aa) |
| | KPNA6 | Importin subunit alpha; Functions in nuclear protein import. (536 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | PSMA7 | Proteasome endopeptidase complex. (216 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (389 aa) |
| | Rfc4 | AAA domain-containing protein. (364 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (504 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | GINS1 | GINS complex subunit 1. (197 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (351 aa) |
| | Psmc6 | 26S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa) |
| | RCBTB2 | RCC1 and BTB domain containing protein 2. (551 aa) |
| | Psmb6 | Proteasome subunit beta. (239 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | Rbx1 | RING-type domain-containing protein. (108 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (862 aa) |
| | Pold4 | Uncharacterized protein. (107 aa) |
| | PSMA8 | Proteasome subunit alpha type. (257 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (473 aa) |
| | Anapc11 | RING-type domain-containing protein. (84 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1897 aa) |
| | PSMB11 | Proteasome subunit beta. (293 aa) |
| | I3MU87_ICTTR | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (250 aa) |
| | I3MUA8_ICTTR | AAA domain-containing protein. (312 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (724 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2282 aa) |
| | ORC2 | Origin recognition complex subunit 2. (578 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (592 aa) |
| | LOC101957760 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC101957469 | Histone H2B type 1-K. (126 aa) |
| | RFC2 | Replication factor C subunit 2. (321 aa) |
| | I3N110_ICTTR | RING-type domain-containing protein. (147 aa) |
| | I3N1R8_ICTTR | Uncharacterized protein. (199 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | LOC101966763 | Ubiquitin-like domain-containing protein. (156 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (503 aa) |
| | KPNA1 | Importin subunit alpha; Functions in nuclear protein import. (538 aa) |
| | TM7SF3 | Transmembrane 7 superfamily member 3. (570 aa) |
| | Pole3 | CBFD_NFYB_HMF domain-containing protein. (147 aa) |
| | Tm4sf19 | Uncharacterized protein. (210 aa) |
| | LOC101967492 | Uncharacterized protein; Belongs to the SKP1 family. (163 aa) |
| | MEIOB | Meiosis specific with OB-fold. (471 aa) |
| | Pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | UBE2S | Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa) |
| | CDC16 | Cell division cycle 16. (614 aa) |
| | CDC7 | Cell division cycle 7; Belongs to the protein kinase superfamily. (498 aa) |
| | GINS2 | GINS complex subunit 2. (141 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (493 aa) |
| | ENSSTOP00000028703 | Ubiquitin-like domain-containing protein. (122 aa) |
| | ENSSTOP00000028717 | RING-type domain-containing protein. (95 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | Mcm8 | MCM domain-containing protein; Belongs to the MCM family. (833 aa) |
| | ENSSTOP00000029537 | Proteasome subunit beta. (200 aa) |
| | ENSSTOP00000029771 | AAA domain-containing protein. (336 aa) |
| | ENSSTOP00000030001 | AAA domain-containing protein. (334 aa) |
| | ENSSTOP00000030245 | Uncharacterized protein. (174 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | ENSSTOP00000030603 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (183 aa) |
| | ENSSTOP00000031366 | Ubiquitin-like domain-containing protein. (95 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | Psmc1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) |
| | ENSSTOP00000031690 | ANK_REP_REGION domain-containing protein. (189 aa) |
| | ENSSTOP00000031840 | Zf-primase domain-containing protein. (205 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (830 aa) |
| | UBE2C | Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | DBF4 | DBF4 zinc finger. (570 aa) |
| | ANAPC15 | Anaphase promoting complex subunit 15. (151 aa) |
| | LOC101972712 | Histone H2B type 1. (126 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | ENSSTOP00000024305 | Uncharacterized protein. (210 aa) |
| | Rfc5 | AAA domain-containing protein. (340 aa) |
| | Pola1 | DNA polymerase. (767 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (376 aa) |
| | LOC101972090 | AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | ENSSTOP00000025153 | PROTEASOME_ALPHA_1 domain-containing protein. (87 aa) |
| | ENSSTOP00000025372 | CBFD_NFYB_HMF domain-containing protein. (134 aa) |
| | PSME1 | Proteasome activator subunit 1. (249 aa) |
| | PSME3 | Proteasome activator subunit 3. (254 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (115 aa) |
| | LIG1 | DNA ligase. (922 aa) |
