STRINGSTRING
PSMD7 PSMD7 PSMD6 PSMD6 PSMC4 PSMC4 PSMA7 PSMA7 PSMB4 PSMB4 Psma6 Psma6 CHEK2 CHEK2 Psmd9 Psmd9 PSMC3 PSMC3 PSMB1 PSMB1 CCNE1 CCNE1 Rps27a Rps27a PSMD1 PSMD1 Psmc5 Psmc5 PSME4 PSME4 COP1 COP1 CCNA2 CCNA2 CDK3 CDK3 PSMB5 PSMB5 PSMA1 PSMA1 PSMC2 PSMC2 UBA52 UBA52 ATM ATM CCNE2 CCNE2 Mdm4 Mdm4 PSMD10 PSMD10 CCNA1 CCNA1 PSMB9 PSMB9 PSMB10 PSMB10 PSMB2 PSMB2 PSMD4 PSMD4 ZNF385B ZNF385B ENSSTOP00000031690 ENSSTOP00000031690 Psmc1 Psmc1 PSMD12 PSMD12 ENSSTOP00000031366 ENSSTOP00000031366 ENSSTOP00000030001 ENSSTOP00000030001 ENSSTOP00000029537 ENSSTOP00000029537 CDK2 CDK2 PSMA4 PSMA4 ENSSTOP00000028703 ENSSTOP00000028703 ENSSTOP00000028075 ENSSTOP00000028075 PSME2 PSME2 PSMD11 PSMD11 PSMA5 PSMA5 PSME3 PSME3 PSME1 PSME1 ENSSTOP00000025153 ENSSTOP00000025153 PSMD2 PSMD2 LOC101972090 LOC101972090 PSMD13 PSMD13 ENSSTOP00000024463 ENSSTOP00000024463 ENSSTOP00000024305 ENSSTOP00000024305 PSMB3 PSMB3 PSMF1 PSMF1 PSMD3 PSMD3 ZNF385C ZNF385C PHF20 PHF20 PSMB8 PSMB8 TP53 TP53 LOC101966763 LOC101966763 CDKN1A CDKN1A I3N1R8_ICTTR I3N1R8_ICTTR I3MUQ5_ICTTR I3MUQ5_ICTTR PSMB11 PSMB11 ZNF385A ZNF385A CDKN1B CDKN1B PSMA8 PSMA8 PSMD14 PSMD14 Psmb6 Psmb6 Mdm2 Mdm2 Psmc6 Psmc6 PSMD8 PSMD8 PSMB7 PSMB7 PSMA3 PSMA3 PSMA2 PSMA2 PSMD5 PSMD5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Psma6Proteasome subunit alpha type. (148 aa)
CHEK2Checkpoint kinase 2. (545 aa)
Psmd9PDZ domain-containing protein. (223 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
PSMB1Proteasome subunit beta. (240 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
Psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
COP1COP1 E3 ubiquitin ligase. (641 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (420 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (304 aa)
PSMB5Proteasome subunit beta. (220 aa)
PSMA1Proteasome subunit alpha type. (266 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ATMATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2618 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
Mdm4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa)
PSMD10ANK_REP_REGION domain-containing protein. (226 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
ZNF385BZinc finger protein 385B. (486 aa)
ENSSTOP00000031690ANK_REP_REGION domain-containing protein. (189 aa)
Psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
ENSSTOP00000030001AAA domain-containing protein. (334 aa)
ENSSTOP00000029537Proteasome subunit beta. (200 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
ENSSTOP00000028075Uncharacterized protein. (77 aa)
PSME2Proteasome activator subunit 2. (239 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSME3Proteasome activator subunit 3. (254 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ENSSTOP00000025153PROTEASOME_ALPHA_1 domain-containing protein. (87 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
LOC101972090AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
ENSSTOP00000024463RING-type domain-containing protein. (209 aa)
ENSSTOP00000024305Uncharacterized protein. (210 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
ZNF385CZinc finger protein 385C. (418 aa)
PHF20PHD finger protein 20. (1013 aa)
PSMB8Proteasome subunit beta. (276 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (162 aa)
I3N1R8_ICTTRUncharacterized protein. (199 aa)
I3MUQ5_ICTTRRING-type domain-containing protein. (239 aa)
PSMB11Proteasome subunit beta. (293 aa)
ZNF385AZinc finger protein 385A. (385 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
PSMA8Proteasome subunit alpha type. (257 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
Psmb6Proteasome subunit beta. (239 aa)
Mdm2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa)
Psmc626S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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