68 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
	PSMD6	Proteasome 26S subunit, non-ATPase 6. (389 aa)
	Rbx1	RING-type domain-containing protein. (108 aa)
	PSMA8	Proteasome subunit alpha type. (257 aa)
	PSMB11	Proteasome subunit beta. (293 aa)
	I3N110_ICTTR	RING-type domain-containing protein. (147 aa)
	I3N1R8_ICTTR	Uncharacterized protein. (199 aa)
	LOC101966763	Ubiquitin-like domain-containing protein. (156 aa)
	FBXL18	F-box and leucine rich repeat protein 18. (740 aa)
	PSMB8	Proteasome subunit beta. (276 aa)
	FBXL6	F-box and leucine rich repeat protein 6. (544 aa)
	LOC101967492	Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
	PSMD3	Proteasome 26S subunit, non-ATPase 3. (534 aa)
	PSMF1	Proteasome inhibitor subunit 1. (271 aa)
	PSMB3	Proteasome subunit beta. (205 aa)
	ENSSTOP00000024305	Uncharacterized protein. (210 aa)
	PSMD13	Proteasome 26S subunit, non-ATPase 13. (376 aa)
	LOC101972090	AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
	PSMD2	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
	ENSSTOP00000025153	PROTEASOME_ALPHA_1 domain-containing protein. (87 aa)
	PSME1	Proteasome activator subunit 1. (249 aa)
	PSME3	Proteasome activator subunit 3. (254 aa)
	ENSSTOP00000026345	Protein kinase domain-containing protein. (386 aa)
	PSMA5	Proteasome subunit alpha type. (241 aa)
	PSMD11	Proteasome 26S subunit, non-ATPase 11. (422 aa)
	PSME2	Proteasome activator subunit 2. (239 aa)
	ENSSTOP00000028703	Ubiquitin-like domain-containing protein. (122 aa)
	ENSSTOP00000028717	RING-type domain-containing protein. (95 aa)
	PSMA4	Proteasome subunit alpha type. (261 aa)
	ENSSTOP00000029537	Proteasome subunit beta. (200 aa)
	ENSSTOP00000030001	AAA domain-containing protein. (334 aa)
	PSMD5	Proteasome 26S subunit, non-ATPase 5. (504 aa)
	ENSSTOP00000031366	Ubiquitin-like domain-containing protein. (95 aa)
	PSMD12	Proteasome 26S subunit, non-ATPase 12. (456 aa)
	Psmc1	AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
	ENSSTOP00000031690	ANK_REP_REGION domain-containing protein. (189 aa)
	PSMC4	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
	PSMA7	Proteasome endopeptidase complex. (216 aa)
	PSMB4	Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
	Aurka	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (363 aa)
	MPPE1	Metallophosphoesterase 1. (391 aa)
	Psma6	Proteasome subunit alpha type. (148 aa)
	Psmd9	PDZ domain-containing protein. (223 aa)
	PSMC3	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
	PSMB1	Proteasome subunit beta. (240 aa)
	Rps27a	Ubiquitin-like domain-containing protein. (156 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
	Psmc5	AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
	PSME4	Proteasome activator subunit 4. (1840 aa)
	PSMB5	Proteasome subunit beta. (220 aa)
	FBXL7	F-box and leucine rich repeat protein 7. (491 aa)
	PSMA1	Proteasome subunit alpha type. (266 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	PSMC2	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	PSMD10	ANK_REP_REGION domain-containing protein. (226 aa)
	PSMB9	Proteasome subunit beta. (219 aa)
	PSMB10	Proteasome subunit beta. (273 aa)
	PSMB2	Proteasome subunit beta. (201 aa)
	PSMD4	Proteasome 26S subunit, non-ATPase 4. (378 aa)
	PSMD14	Proteasome 26S subunit, non-ATPase 14. (310 aa)
	Psmb6	Proteasome subunit beta. (239 aa)
	Psmc6	26S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa)
	PSMD8	Proteasome 26S subunit, non-ATPase 8. (351 aa)
	PSMB7	Proteasome subunit beta. (277 aa)
	PSMA3	Proteasome subunit alpha type. (255 aa)
	PSMA2	Proteasome subunit alpha type. (234 aa)
	PSMD7	Proteasome 26S subunit, non-ATPase 7. (324 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Aurka	CUL1	ENSSTOP00000010729	ENSSTOP00000005323	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cullin 1; Belongs to the cullin family.	0.696
Aurka	ENSSTOP00000024305	ENSSTOP00000010729	ENSSTOP00000024305	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.505
Aurka	ENSSTOP00000025153	ENSSTOP00000010729	ENSSTOP00000025153	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	PROTEASOME_ALPHA_1 domain-containing protein.	0.505
Aurka	ENSSTOP00000028717	ENSSTOP00000010729	ENSSTOP00000028717	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	RING-type domain-containing protein.	0.524
Aurka	ENSSTOP00000030001	ENSSTOP00000010729	ENSSTOP00000030001	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	AAA domain-containing protein.	0.544
Aurka	ENSSTOP00000031366	ENSSTOP00000010729	ENSSTOP00000031366	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Ubiquitin-like domain-containing protein.	0.543
Aurka	FBXL6	ENSSTOP00000010729	ENSSTOP00000019991	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	F-box and leucine rich repeat protein 6.	0.614
Aurka	FBXL7	ENSSTOP00000010729	ENSSTOP00000005951	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	F-box and leucine rich repeat protein 7.	0.619
Aurka	I3N110_ICTTR	ENSSTOP00000010729	ENSSTOP00000018056	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	RING-type domain-containing protein.	0.524
Aurka	I3N1R8_ICTTR	ENSSTOP00000010729	ENSSTOP00000018314	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.520
Aurka	LOC101966763	ENSSTOP00000010729	ENSSTOP00000019666	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Ubiquitin-like domain-containing protein.	0.543
Aurka	LOC101967492	ENSSTOP00000010729	ENSSTOP00000021996	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the SKP1 family.	0.626
Aurka	LOC101972090	ENSSTOP00000010729	ENSSTOP00000025065	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.536
Aurka	PSMA1	ENSSTOP00000010729	ENSSTOP00000005600	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Proteasome subunit alpha type.	0.592
Aurka	PSMA2	ENSSTOP00000010729	ENSSTOP00000011947	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Proteasome subunit alpha type.	0.520
Aurka	PSMA3	ENSSTOP00000010729	ENSSTOP00000012133	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Proteasome subunit alpha type.	0.617
Aurka	PSMA4	ENSSTOP00000010729	ENSSTOP00000028754	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Proteasome subunit alpha type.	0.589
Aurka	PSMA5	ENSSTOP00000010729	ENSSTOP00000026865	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Proteasome subunit alpha type.	0.586
Aurka	PSMA7	ENSSTOP00000010729	ENSSTOP00000011193	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Proteasome endopeptidase complex.	0.547
Aurka	PSMA8	ENSSTOP00000010729	ENSSTOP00000014063	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Proteasome subunit alpha type.	0.547