STRINGSTRING
ADRB2 ADRB2 ENSSTOP00000030319 ENSSTOP00000030319 LOC101969002 LOC101969002 Eps15 Eps15 ENSSTOP00000031366 ENSSTOP00000031366 DAB2 DAB2 GPS1 GPS1 TFRC TFRC VAMP4 VAMP4 NETO2 NETO2 UBA52 UBA52 SYT11 SYT11 CLPB CLPB TOR1B TOR1B CBL CBL COPS2 COPS2 Vamp2 Vamp2 SLC2A8 SLC2A8 COPS3 COPS3 I3M6L1_ICTTR I3M6L1_ICTTR STON2 STON2 VAMP8 VAMP8 VAMP5 VAMP5 EGFR EGFR PPP1R42 PPP1R42 COPS5 COPS5 AGFG2 AGFG2 LDLR LDLR CLHC1 CLHC1 AP2M1 AP2M1 AVPR2 AVPR2 SH3GL1 SH3GL1 DVL2 DVL2 AREG AREG COPS6 COPS6 IGF2R IGF2R SYT4 SYT4 SCARB2 SCARB2 Rps27a Rps27a NECAP1 NECAP1 SYT9 SYT9 SYT2 SYT2 TACR1 TACR1 ZFYVE1 ZFYVE1 AP2A2 AP2A2 Arr3 Arr3 GRB2 GRB2 SH3GL3 SH3GL3 M6PR M6PR NECAP2 NECAP2 BTC BTC UBQLN2 UBQLN2 MCTP1 MCTP1 TF TF GRK2 GRK2 FZD4 FZD4 UBQLN4 UBQLN4 EPN3 EPN3 SYT1 SYT1 ENTHD1 ENTHD1 STAM2 STAM2 I3MV27_ICTTR I3MV27_ICTTR COPS8 COPS8 FCHO1 FCHO1 CD3D CD3D COPS4 COPS4 BMP2K BMP2K AGTR1 AGTR1 LOC101972658 LOC101972658 AVP AVP TOR1A TOR1A FCHO2 FCHO2 CLTB CLTB LOC101966763 LOC101966763 NEDD8 NEDD8 ITSN1 ITSN1 APOB APOB WNT5A WNT5A EPN1 EPN1 SLC18A3 SLC18A3 REPS1 REPS1 LDLRAP1 LDLRAP1 COPS7B COPS7B Vamp7 Vamp7 STAM STAM UBQLN3 UBQLN3 CD4 CD4 Tgoln2 Tgoln2 SH3KBP1 SH3KBP1 MCTP2 MCTP2 CHRM2 CHRM2 COPS7A COPS7A SYT8 SYT8 HBEGF HBEGF PICALM PICALM AP2A1 AP2A1 ARRB2 ARRB2 ARRB1 ARRB1 TGFA TGFA ENSSTOP00000025215 ENSSTOP00000025215 CLTC CLTC UBQLN1 UBQLN1 Zfyve19 Zfyve19 EPS15L1 EPS15L1 GPR21 GPR21 EPN2 EPN2 SGIP1 SGIP1 CLTA CLTA KIAA0319 KIAA0319 Vamp3 Vamp3 ENSSTOP00000028703 ENSSTOP00000028703 LRP2 LRP2 NETO1 NETO1 Ston1 Ston1 AAK1 AAK1 EPGN EPGN CLTCL1 CLTCL1 LMBRD2 LMBRD2 AP2B1 AP2B1 REPS2 REPS2 KIAA0319L KIAA0319L SNAP91 SNAP91 GRK3 GRK3 UBL7 UBL7 UBQLNL UBQLNL EREG EREG HGS HGS ITSN2 ITSN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADRB2Adrenoceptor beta 2. (416 aa)
ENSSTOP00000030319Uncharacterized protein. (2101 aa)
LOC101969002Uncharacterized protein. (639 aa)
Eps15Uncharacterized protein. (925 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
DAB2DAB adaptor protein 2. (767 aa)
GPS1G protein pathway suppressor 1. (445 aa)
TFRCTransferrin receptor. (760 aa)
VAMP4Vesicle associated membrane protein 4. (141 aa)
NETO2Neuropilin and tolloid like 2. (520 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
SYT11Synaptotagmin 11. (419 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (708 aa)
TOR1BTorsin. (323 aa)
CBLCbl proto-oncogene. (870 aa)
COPS2COP9 signalosome subunit 2. (443 aa)
Vamp2V-SNARE coiled-coil homology domain-containing protein. (140 aa)
SLC2A8Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (478 aa)
COPS3COP9 signalosome subunit 3. (423 aa)
I3M6L1_ICTTRABC transmembrane type-1 domain-containing protein. (528 aa)
STON2Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (899 aa)
VAMP8Vesicle associated membrane protein 8. (141 aa)
VAMP5Vesicle associated membrane protein 5. (97 aa)
EGFRReceptor protein-tyrosine kinase. (1192 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (321 aa)
COPS5COP9 signalosome subunit 5. (334 aa)
AGFG2ArfGAP with FG repeats 2. (479 aa)
LDLRLow density lipoprotein receptor. (863 aa)
CLHC1Clathrin heavy chain linker domain containing 1. (599 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (435 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (371 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (368 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
AREGAmphiregulin. (252 aa)
COPS6COP9 signalosome subunit 6. (297 aa)
IGF2RInsulin like growth factor 2 receptor. (2452 aa)
SYT4Synaptotagmin 4. (424 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (428 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
NECAP1NECAP endocytosis associated 1. (275 aa)
SYT9Synaptotagmin 9. (491 aa)
SYT2Synaptotagmin 2. (419 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (777 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (914 aa)
Arr3Arrestin-C; May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins (By similarity). (393 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (346 aa)
M6PRMannose-6-phosphate receptor, cation dependent. (231 aa)
NECAP2NECAP endocytosis associated 2. (265 aa)
BTCBetacellulin. (143 aa)
UBQLN2Ubiquilin 2. (627 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (952 aa)
TFTransferrin; Belongs to the transferrin family. (694 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (690 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
UBQLN4Ubiquilin 4. (589 aa)
EPN3Epsin 3. (636 aa)
SYT1Synaptotagmin 1. (422 aa)
ENTHD1ENTH domain containing 1. (595 aa)
STAM2Signal transducing adaptor molecule 2. (524 aa)
I3MV27_ICTTRV-SNARE coiled-coil homology domain-containing protein. (97 aa)
COPS8COP9 signalosome subunit 8. (209 aa)
FCHO1FCH domain only 1. (738 aa)
CD3DCD3d molecule. (170 aa)
COPS4COP9 signalosome subunit 4. (406 aa)
BMP2KBMP2 inducible kinase. (1130 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (360 aa)
LOC101972658Uncharacterized protein. (495 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (145 aa)
TOR1ATorsin. (311 aa)
FCHO2FCH domain only 2. (799 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
NEDD8NEDD8 ubiquitin like modifier. (81 aa)
ITSN1Intersectin 1. (1655 aa)
APOBApolipoprotein B. (4482 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
EPN1Epsin 1. (576 aa)
SLC18A3Solute carrier family 18 member A3. (531 aa)
REPS1RALBP1 associated Eps domain containing 1. (736 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (308 aa)
COPS7BCOP9 signalosome subunit 7B. (264 aa)
Vamp7Uncharacterized protein; Belongs to the synaptobrevin family. (220 aa)
STAMSignal transducing adaptor molecule. (535 aa)
UBQLN3Ubiquilin 3. (655 aa)
CD4CD4 molecule. (451 aa)
Tgoln2Uncharacterized protein. (335 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (690 aa)
MCTP2Multiple C2 and transmembrane domain containing 2. (878 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
COPS7ACOP9 signalosome subunit 7A. (275 aa)
SYT8Synaptotagmin 8. (387 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (660 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (978 aa)
ARRB2Arrestin beta 2. (409 aa)
ARRB1Arrestin beta 1. (418 aa)
TGFATransforming growth factor alpha. (159 aa)
ENSSTOP00000025215Uncharacterized protein; Belongs to the synaptobrevin family. (185 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1687 aa)
UBQLN1Ubiquilin 1. (557 aa)
Zfyve19Uncharacterized protein. (280 aa)
EPS15L1Epidermal growth factor receptor pathway substrate 15 like 1. (935 aa)
GPR21G protein-coupled receptor 21; Belongs to the G-protein coupled receptor 1 family. (348 aa)
EPN2Epsin 2. (648 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1. (846 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
KIAA0319KIAA0319. (901 aa)
Vamp3V-SNARE coiled-coil homology domain-containing protein. (106 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
LRP2LDL receptor related protein 2. (4656 aa)
NETO1Neuropilin and tolloid like 1. (540 aa)
Ston1Stonin-1; May be involved in the endocytic machinery. (735 aa)
AAK1AP2 associated kinase 1. (982 aa)
EPGNEpithelial mitogen. (153 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1667 aa)
LMBRD2LMBR1 domain containing 2. (688 aa)
AP2B1AP complex subunit beta. (951 aa)
REPS2RALBP1 associated Eps domain containing 2. (589 aa)
KIAA0319LKIAA0319 like. (1046 aa)
SNAP91Synaptosome associated protein 91. (902 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (619 aa)
UBL7Ubiquitin like 7. (380 aa)
UBQLNLUbiquilin like. (600 aa)
EREGEpiregulin. (163 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (776 aa)
ITSN2Intersectin 2. (1655 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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