STRINGSTRING
ENSSTOP00000024190 ENSSTOP00000024190 Rhoa Rhoa BCAR1 BCAR1 ERBB2 ERBB2 Cdk4 Cdk4 DOK1 DOK1 RASA1 RASA1 LRRK2 LRRK2 EREG EREG CCND1 CCND1 ERBB4 ERBB4 RNF222 RNF222 STAP2 STAP2 ERBB3 ERBB3 HBEGF HBEGF DOCK1 DOCK1 UBA52 UBA52 CRK CRK NRG4 NRG4 LOC101975023 LOC101975023 LOC101964641 LOC101964641 AKT1 AKT1 HRAS HRAS ENSSTOP00000028703 ENSSTOP00000028703 CDK2 CDK2 PSPC1 PSPC1 ELMO3 ELMO3 ENSSTOP00000030902 ENSSTOP00000030902 Csde1 Csde1 ENSSTOP00000031366 ENSSTOP00000031366 NRG1 NRG1 ELMOD1 ELMOD1 EGFR EGFR ELMO1 ELMO1 CBL CBL Hif1a Hif1a STAT3 STAT3 RAC1 RAC1 PTK6 PTK6 SRMS SRMS GPNMB GPNMB KHDRBS3 KHDRBS3 ELMOD3 ELMOD3 KRAS KRAS Rps27a Rps27a CCNE1 CCNE1 SOCS3 SOCS3 ARHGAP35 ARHGAP35 KHDRBS2 KHDRBS2 ELMO2 ELMO2 Sfpq Sfpq BTC BTC PXN PXN KHDRBS1 KHDRBS1 ARAP1 ARAP1 LPXN LPXN NONO NONO CDKN1B CDKN1B NRAS NRAS TGFB1I1 TGFB1I1 NRG2 NRG2 LOC101959358 LOC101959358 LOC101974931 LOC101974931 LOC101966763 LOC101966763 PTPN1 PTPN1 ERAS ERAS ELMOD2 ELMOD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSSTOP00000024190Protein kinase domain-containing protein. (266 aa)
RhoaRas homolog family member A. (193 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (874 aa)
ERBB2Receptor protein-tyrosine kinase. (1256 aa)
Cdk4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
DOK1Docking protein 1. (496 aa)
RASA1RAS p21 protein activator 1. (1030 aa)
LRRK2Leucine rich repeat kinase 2. (2520 aa)
EREGEpiregulin. (163 aa)
CCND1Cyclin D1. (250 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
RNF222Ring finger protein 222. (211 aa)
STAP2Signal transducing adaptor family member 2. (409 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1248 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1849 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
CRKCRK proto-oncogene, adaptor protein. (305 aa)
NRG4Neuregulin 4. (123 aa)
LOC101975023CSD_1 domain-containing protein. (729 aa)
LOC101964641Uncharacterized protein. (400 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
PSPC1Paraspeckle component 1. (523 aa)
ELMO3Engulfment and cell motility 3. (720 aa)
ENSSTOP00000030902Uncharacterized protein. (380 aa)
Csde1Uncharacterized protein. (555 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
NRG1Neuregulin 1. (700 aa)
ELMOD1ELMO domain containing 1. (326 aa)
EGFRReceptor protein-tyrosine kinase. (1192 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
CBLCbl proto-oncogene. (870 aa)
Hif1aUncharacterized protein. (821 aa)
STAT3Signal transducer and activator of transcription. (748 aa)
RAC1Rac family small GTPase 1. (211 aa)
PTK6Tyrosine-protein kinase. (450 aa)
SRMSTyrosine-protein kinase. (534 aa)
GPNMBGlycoprotein nmb. (556 aa)
KHDRBS3KH RNA binding domain containing, signal transduction associated 3. (346 aa)
ELMOD3ELMO domain containing 3. (364 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
SOCS3Suppressor of cytokine signaling 3. (227 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
KHDRBS2KH RNA binding domain containing, signal transduction associated 2. (349 aa)
ELMO2Engulfment and cell motility 2. (732 aa)
SfpqRRM domain-containing protein. (351 aa)
BTCBetacellulin. (143 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (424 aa)
KHDRBS1KH RNA binding domain containing, signal transduction associated 1. (443 aa)
ARAP1ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1440 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
NONONon-POU domain containing octamer binding. (470 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (479 aa)
NRG2Neuregulin 2. (767 aa)
LOC101959358Uncharacterized protein. (193 aa)
LOC101974931Tyrosine-protein phosphatase non-receptor type. (433 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (413 aa)
ERASES cell expressed Ras. (227 aa)
ELMOD2ELMO domain containing 2. (260 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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