STRINGSTRING
ID3 ID3 Trib2 Trib2 FOSL1 FOSL1 EGR2 EGR2 Chd4 Chd4 RRAD RRAD ELK1 ELK1 SRF SRF CREB1 CREB1 NAB2 NAB2 Sgk1 Sgk1 TRIB1 TRIB1 EGR1 EGR1 EGR3 EGR3 LYL1 LYL1 EGR4 EGR4 CDK5R2 CDK5R2 ASCL2 ASCL2 ASCL1 ASCL1 ID2 ID2 I3NC46_ICTTR I3NC46_ICTTR ARC ARC FOSB FOSB JUNB JUNB ENSSTOP00000026011 ENSSTOP00000026011 ENSSTOP00000028027 ENSSTOP00000028027 NAB1 NAB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
Trib2Protein kinase domain-containing protein. (343 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (275 aa)
EGR2Early growth response 2. (423 aa)
Chd4Uncharacterized protein. (1909 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
ELK1ETS transcription factor ELK1. (428 aa)
SRFSerum response factor. (505 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
NAB2NGFI-A binding protein 2. (525 aa)
Sgk1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (454 aa)
TRIB1Tribbles pseudokinase 1. (372 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
EGR3Early growth response 3. (387 aa)
LYL1LYL1 basic helix-loop-helix family member. (279 aa)
EGR4Early growth response 4. (484 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (367 aa)
ASCL2Achaete-scute family bHLH transcription factor 2. (190 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (234 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
I3NC46_ICTTRNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (397 aa)
ARCActivity regulated cytoskeleton associated protein. (391 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
ENSSTOP00000026011BHLH domain-containing protein. (102 aa)
ENSSTOP00000028027Protein kinase domain-containing protein. (300 aa)
NAB1NGFI-A binding protein 1. (487 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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