STRINGSTRING
PDE6D PDE6D GOLGA7 GOLGA7 UBA52 UBA52 KRAS KRAS Rps27a Rps27a I3MGY8_ICTTR I3MGY8_ICTTR Fnta Fnta GOLGA7B GOLGA7B ICMT ICMT NRAS NRAS Abhd17c Abhd17c ZDHHC14 ZDHHC14 RCE1 RCE1 PRKCQ PRKCQ LOC101960833 LOC101960833 LOC101966763 LOC101966763 ARL2 ARL2 Arl13a Arl13a ZDHHC18 ZDHHC18 ERAS ERAS ZDHHC9 ZDHHC9 LOC101970445 LOC101970445 Fntb Fntb ENSSTOP00000024359 ENSSTOP00000024359 Bcl2l1 Bcl2l1 USP42 USP42 ABHD17B ABHD17B ENSSTOP00000026508 ENSSTOP00000026508 LOC101975023 LOC101975023 LYPLA1 LYPLA1 HRAS HRAS ENSSTOP00000028703 ENSSTOP00000028703 BCL2L2 BCL2L2 Csde1 Csde1 ABHD17A ABHD17A ENSSTOP00000031366 ENSSTOP00000031366
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDE6DRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...] (150 aa)
GOLGA7Golgin A7. (137 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
I3MGY8_ICTTRAGC-kinase C-terminal domain-containing protein. (107 aa)
FntaUncharacterized protein. (379 aa)
GOLGA7BGolgin A7 family member B. (126 aa)
ICMTProtein-S-isoprenylcysteine O-methyltransferase. (271 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
Abhd17cUncharacterized protein. (94 aa)
ZDHHC14Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (489 aa)
RCE1Ras converting CAAX endopeptidase 1. (329 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
LOC101960833Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (527 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
ARL2ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
Arl13aUncharacterized protein. (375 aa)
ZDHHC18Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (354 aa)
ERASES cell expressed Ras. (227 aa)
ZDHHC9Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (364 aa)
LOC101970445Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (527 aa)
FntbProtein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. (471 aa)
ENSSTOP00000024359Uncharacterized protein. (354 aa)
Bcl2l1BH4_2 domain-containing protein. (233 aa)
USP42Ubiquitin specific peptidase 42; Belongs to the peptidase C19 family. (1331 aa)
ABHD17BAbhydrolase domain containing 17B. (288 aa)
ENSSTOP00000026508BH4_2 domain-containing protein. (224 aa)
LOC101975023CSD_1 domain-containing protein. (729 aa)
LYPLA1Lysophospholipase 1. (230 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
BCL2L2BCL2 like 2. (193 aa)
Csde1Uncharacterized protein. (555 aa)
ABHD17AAbhydrolase domain containing 17A. (310 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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