STRINGSTRING
Fbxl17 Fbxl17 SESN2 SESN2 PSMD1 PSMD1 PSMB2 PSMB2 PSMB10 PSMB10 UFD1 UFD1 AKT2 AKT2 PSMB9 PSMB9 PSMD10 PSMD10 BACH1 BACH1 UBA52 UBA52 TRIM21 TRIM21 CREBBP CREBBP BACH2 BACH2 PSMC2 PSMC2 CUL1 CUL1 PSMA1 PSMA1 PSMB5 PSMB5 PSME4 PSME4 Psmc5 Psmc5 SQSTM1 SQSTM1 ENSSTOP00000031690 ENSSTOP00000031690 Psmc1 Psmc1 PSMD12 PSMD12 NFE2L1 NFE2L1 ENSSTOP00000031366 ENSSTOP00000031366 SKP1 SKP1 ENSSTOP00000030001 ENSSTOP00000030001 ENSSTOP00000029537 ENSSTOP00000029537 PSMA4 PSMA4 ENSSTOP00000028717 ENSSTOP00000028717 ENSSTOP00000028703 ENSSTOP00000028703 AKT1 AKT1 PSME2 PSME2 PSMD11 PSMD11 PSMA5 PSMA5 Ubxn7 Ubxn7 LOC101964795 LOC101964795 PSME3 PSME3 PSME1 PSME1 ENSSTOP00000025153 ENSSTOP00000025153 PSMD2 PSMD2 LOC101972090 LOC101972090 PSMD13 PSMD13 MUL1 MUL1 ENSSTOP00000024305 ENSSTOP00000024305 PSMB3 PSMB3 PRDX1 PRDX1 ATF4 ATF4 SPATA5L1 SPATA5L1 PSMF1 PSMF1 GSK3B GSK3B PSMD3 PSMD3 LOC101967492 LOC101967492 BTRC BTRC PSMB8 PSMB8 LOC101966763 LOC101966763 CDKN1A CDKN1A I3N1R8_ICTTR I3N1R8_ICTTR MTFP1 MTFP1 I3N110_ICTTR I3N110_ICTTR NPLOC4 NPLOC4 SRXN1 SRXN1 MAFK MAFK SESN1 SESN1 KLHL18 KLHL18 PSMB11 PSMB11 SPATA5 SPATA5 PSMA8 PSMA8 Rbx1 Rbx1 CUL3 CUL3 VCP VCP PSMD14 PSMD14 Psmb6 Psmb6 I3MNM5_ICTTR I3MNM5_ICTTR NFE2L3 NFE2L3 Psmc6 Psmc6 PSMD8 PSMD8 KLHL17 KLHL17 PSMB7 PSMB7 PSMA3 PSMA3 PSMA2 PSMA2 PSMD7 PSMD7 PSMD5 PSMD5 PSMD6 PSMD6 PSMC4 PSMC4 PSMA7 PSMA7 PSMB4 PSMB4 Psma6 Psma6 Psmd9 Psmd9 PSMC3 PSMC3 AKT3 AKT3 PSMB1 PSMB1 KEAP1 KEAP1 DPP3 DPP3 NFE2L2 NFE2L2 PSMD4 PSMD4 Rps27a Rps27a EP300 EP300
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Fbxl17Uncharacterized protein. (220 aa)
SESN2Sestrin 2. (479 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMB10Proteasome subunit beta. (273 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (307 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMD10ANK_REP_REGION domain-containing protein. (226 aa)
BACH1BTB domain and CNC homolog 1. (737 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
TRIM21Tripartite motif containing 21. (477 aa)
CREBBPCREB binding protein. (2410 aa)
BACH2BTB domain and CNC homolog 2. (843 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMA1Proteasome subunit alpha type. (266 aa)
PSMB5Proteasome subunit beta. (220 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
Psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
SQSTM1Sequestosome 1. (440 aa)
ENSSTOP00000031690ANK_REP_REGION domain-containing protein. (189 aa)
Psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
NFE2L1Nuclear factor, erythroid 2 like 1. (771 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
ENSSTOP00000030001AAA domain-containing protein. (334 aa)
ENSSTOP00000029537Proteasome subunit beta. (200 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
ENSSTOP00000028717RING-type domain-containing protein. (95 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PSME2Proteasome activator subunit 2. (239 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
Ubxn7UBX domain-containing protein 7. (489 aa)
LOC101964795Uncharacterized protein. (108 aa)
PSME3Proteasome activator subunit 3. (254 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ENSSTOP00000025153PROTEASOME_ALPHA_1 domain-containing protein. (87 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
LOC101972090AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
ENSSTOP00000024305Uncharacterized protein. (210 aa)
PSMB3Proteasome subunit beta. (205 aa)
PRDX1Peroxiredoxin 1. (199 aa)
ATF4Activating transcription factor 4. (352 aa)
SPATA5L1Spermatogenesis associated 5 like 1. (789 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
LOC101967492Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
PSMB8Proteasome subunit beta. (276 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (162 aa)
I3N1R8_ICTTRUncharacterized protein. (199 aa)
MTFP1Mitochondrial fission process 1. (166 aa)
I3N110_ICTTRRING-type domain-containing protein. (147 aa)
NPLOC4NPL4 homolog, ubiquitin recognition factor. (603 aa)
SRXN1Sulfiredoxin. (153 aa)
MAFKMAF bZIP transcription factor K. (156 aa)
SESN1Sestrin 1. (552 aa)
KLHL18Kelch like family member 18. (579 aa)
PSMB11Proteasome subunit beta. (293 aa)
SPATA5Spermatogenesis associated 5. (839 aa)
PSMA8Proteasome subunit alpha type. (257 aa)
Rbx1RING-type domain-containing protein. (108 aa)
CUL3Cullin 3; Belongs to the cullin family. (776 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
Psmb6Proteasome subunit beta. (239 aa)
I3MNM5_ICTTRUncharacterized protein. (131 aa)
NFE2L3Nuclear factor, erythroid 2 like 3. (677 aa)
Psmc626S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
KLHL17Kelch like family member 17. (641 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Psma6Proteasome subunit alpha type. (148 aa)
Psmd9PDZ domain-containing protein. (223 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PSMB1Proteasome subunit beta. (240 aa)
KEAP1Kelch like ECH associated protein 1. (624 aa)
DPP3Dipeptidyl peptidase 3; Belongs to the peptidase M49 family. (737 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (600 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
EP300E1A binding protein p300. (2423 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.