(20 nodes) TGF-beta propeptide network (Ictidomys tridecemlineatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MSTN	Myostatin. (376 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	BMP5	Bone morphogenetic protein 5. (454 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	BMP10	Bone morphogenetic protein 10. (422 aa)
	BMP3	Bone morphogenetic protein 3. (487 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	NODAL	Nodal growth differentiation factor. (350 aa)
	BMP6	Bone morphogenetic protein 6. (507 aa)
	GDF6	Growth differentiation factor 6. (460 aa)
	BMP2	Bone morphogenetic protein 2. (395 aa)
	GDF7	Growth differentiation factor 7. (445 aa)
	INHBB	Inhibin subunit beta B. (336 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	GDF2	Growth differentiation factor 2. (429 aa)
	GDF5	Growth differentiation factor 5. (495 aa)
	LOC101961346	Left-right determination factor. (363 aa)
	GDF11	Growth differentiation factor 11. (387 aa)
	LOC101962293	Left-right determination factor. (367 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP10	BMP2	ENSSTOP00000009290	ENSSTOP00000018746	Bone morphogenetic protein 10.	Bone morphogenetic protein 2.	0.509
BMP10	BMP4	ENSSTOP00000009290	ENSSTOP00000001023	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.480
BMP10	BMP5	ENSSTOP00000009290	ENSSTOP00000002171	Bone morphogenetic protein 10.	Bone morphogenetic protein 5.	0.505
BMP10	BMP6	ENSSTOP00000009290	ENSSTOP00000017540	Bone morphogenetic protein 10.	Bone morphogenetic protein 6.	0.432
BMP10	BMP7	ENSSTOP00000009290	ENSSTOP00000011380	Bone morphogenetic protein 10.	Bone morphogenetic protein 7.	0.463
BMP10	GDF2	ENSSTOP00000009290	ENSSTOP00000022676	Bone morphogenetic protein 10.	Growth differentiation factor 2.	0.771
BMP10	GDF5	ENSSTOP00000009290	ENSSTOP00000022883	Bone morphogenetic protein 10.	Growth differentiation factor 5.	0.479
BMP10	GDF6	ENSSTOP00000009290	ENSSTOP00000018656	Bone morphogenetic protein 10.	Growth differentiation factor 6.	0.472
BMP2	BMP10	ENSSTOP00000018746	ENSSTOP00000009290	Bone morphogenetic protein 2.	Bone morphogenetic protein 10.	0.509
BMP2	BMP4	ENSSTOP00000018746	ENSSTOP00000001023	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.887
BMP2	BMP5	ENSSTOP00000018746	ENSSTOP00000002171	Bone morphogenetic protein 2.	Bone morphogenetic protein 5.	0.788
BMP2	BMP6	ENSSTOP00000018746	ENSSTOP00000017540	Bone morphogenetic protein 2.	Bone morphogenetic protein 6.	0.919
BMP2	BMP7	ENSSTOP00000018746	ENSSTOP00000011380	Bone morphogenetic protein 2.	Bone morphogenetic protein 7.	0.893
BMP2	GDF2	ENSSTOP00000018746	ENSSTOP00000022676	Bone morphogenetic protein 2.	Growth differentiation factor 2.	0.480
BMP2	GDF5	ENSSTOP00000018746	ENSSTOP00000022883	Bone morphogenetic protein 2.	Growth differentiation factor 5.	0.729
BMP2	GDF6	ENSSTOP00000018746	ENSSTOP00000018656	Bone morphogenetic protein 2.	Growth differentiation factor 6.	0.579
BMP4	BMP10	ENSSTOP00000001023	ENSSTOP00000009290	Bone morphogenetic protein 4.	Bone morphogenetic protein 10.	0.480
BMP4	BMP2	ENSSTOP00000001023	ENSSTOP00000018746	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.887
BMP4	BMP5	ENSSTOP00000001023	ENSSTOP00000002171	Bone morphogenetic protein 4.	Bone morphogenetic protein 5.	0.788
BMP4	BMP6	ENSSTOP00000001023	ENSSTOP00000017540	Bone morphogenetic protein 4.	Bone morphogenetic protein 6.	0.919