8 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	ALDOB	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	ATF3	Activating transcription factor 3. (181 aa)
	Ptgs2	EGF-like domain-containing protein. (605 aa)
	EGR1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
	APOLD1	Apolipoprotein L domain containing 1. (248 aa)
	Aldoa	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (417 aa)
	CCND1	Cyclin D1. (250 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDOB	Aldoa	ENSSTOP00000006281	ENSSTOP00000000776	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.905
APOLD1	ATF3	ENSSTOP00000022579	ENSSTOP00000006350	Apolipoprotein L domain containing 1.	Activating transcription factor 3.	0.441
APOLD1	EGR1	ENSSTOP00000022579	ENSSTOP00000016429	Apolipoprotein L domain containing 1.	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	0.457
APOLD1	FOS	ENSSTOP00000022579	ENSSTOP00000002680	Apolipoprotein L domain containing 1.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.452
APOLD1	Ptgs2	ENSSTOP00000022579	ENSSTOP00000008625	Apolipoprotein L domain containing 1.	EGF-like domain-containing protein.	0.613
ATF3	APOLD1	ENSSTOP00000006350	ENSSTOP00000022579	Activating transcription factor 3.	Apolipoprotein L domain containing 1.	0.441
ATF3	EGR1	ENSSTOP00000006350	ENSSTOP00000016429	Activating transcription factor 3.	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	0.643
ATF3	FOS	ENSSTOP00000006350	ENSSTOP00000002680	Activating transcription factor 3.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.961
ATF3	Ptgs2	ENSSTOP00000006350	ENSSTOP00000008625	Activating transcription factor 3.	EGF-like domain-containing protein.	0.440
Aldoa	ALDOB	ENSSTOP00000000776	ENSSTOP00000006281	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.905
CCND1	FOS	ENSSTOP00000000365	ENSSTOP00000002680	Cyclin D1.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.665
EGR1	APOLD1	ENSSTOP00000016429	ENSSTOP00000022579	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Apolipoprotein L domain containing 1.	0.457
EGR1	ATF3	ENSSTOP00000016429	ENSSTOP00000006350	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Activating transcription factor 3.	0.643
EGR1	FOS	ENSSTOP00000016429	ENSSTOP00000002680	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.956
EGR1	Ptgs2	ENSSTOP00000016429	ENSSTOP00000008625	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	EGF-like domain-containing protein.	0.488
FOS	APOLD1	ENSSTOP00000002680	ENSSTOP00000022579	Fos proto-oncogene, AP-1 transcription factor subunit.	Apolipoprotein L domain containing 1.	0.452
FOS	ATF3	ENSSTOP00000002680	ENSSTOP00000006350	Fos proto-oncogene, AP-1 transcription factor subunit.	Activating transcription factor 3.	0.961
FOS	CCND1	ENSSTOP00000002680	ENSSTOP00000000365	Fos proto-oncogene, AP-1 transcription factor subunit.	Cyclin D1.	0.665
FOS	EGR1	ENSSTOP00000002680	ENSSTOP00000016429	Fos proto-oncogene, AP-1 transcription factor subunit.	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	0.956
FOS	Ptgs2	ENSSTOP00000002680	ENSSTOP00000008625	Fos proto-oncogene, AP-1 transcription factor subunit.	EGF-like domain-containing protein.	0.528