STRINGSTRING
NPY NPY FSHB FSHB FOS FOS POMC POMC PER2 PER2 NPAS2 NPAS2 LOC101969021 LOC101969021 CARTPT CARTPT TAS1R3 TAS1R3 PER3 PER3 AGRP AGRP LEP LEP Ins Ins CGA CGA JUN JUN Scoc Scoc QRFP QRFP CRY1 CRY1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NPYNeuropeptide Y. (97 aa)
FSHBFollicle stimulating hormone subunit beta. (130 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
POMCProopiomelanocortin. (212 aa)
PER2Period circadian regulator 2. (1297 aa)
NPAS2Neuronal PAS domain protein 2. (814 aa)
LOC101969021Uncharacterized protein. (216 aa)
CARTPTCART prepropeptide. (129 aa)
TAS1R3Taste 1 receptor member 3. (876 aa)
PER3Period circadian regulator 3. (1062 aa)
AGRPAgouti related neuropeptide. (132 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
InsInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
ScocUncharacterized protein. (125 aa)
QRFPPyroglutamylated RFamide peptide. (108 aa)
CRY1Cryptochrome circadian regulator 1. (609 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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