STRINGSTRING
CDC42BPB CDC42BPB GRK3 GRK3 STK38L STK38L DMPK DMPK PRKACA PRKACA GRK5 GRK5 PRKCI PRKCI AKT2 AKT2 PRKCA PRKCA SGK3 SGK3 PRKCD PRKCD RPS6KA2 RPS6KA2 PKN2 PKN2 GRK6 GRK6 CIT CIT MAST1 MAST1 Prkch Prkch GRK4 GRK4 CDC42BPG CDC42BPG SGK2 SGK2 RPS6KA3 RPS6KA3 AKT3 AKT3 MASTL MASTL I3MGY8_ICTTR I3MGY8_ICTTR STK38 STK38 PRKCB PRKCB PRKCE PRKCE PRKCZ PRKCZ LATS1 LATS1 CDC42BPA CDC42BPA GRK2 GRK2 MAST3 MAST3 Sgk1 Sgk1 GRK1 GRK1 MAST2 MAST2 Prkx Prkx RPS6KB2 RPS6KB2 PRKCQ PRKCQ ROCK1 ROCK1 Grk7 Grk7 LATS2 LATS2 Rps6kb1 Rps6kb1 I3NC46_ICTTR I3NC46_ICTTR RPS6KA4 RPS6KA4 PRKCG PRKCG PKN1 PKN1 PKN3 PKN3 AKT1 AKT1 PRKACB PRKACB RPS6KA5 RPS6KA5 PRKG1 PRKG1 MAST4 MAST4 RPS6KA6 RPS6KA6 RPS6KA1 RPS6KA1 ROCK2 ROCK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1623 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (619 aa)
STK38LNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (464 aa)
DMPKDM1 protein kinase. (629 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (334 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (572 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa)
SGK3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
PKN2Protein kinase N2. (982 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (569 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2054 aa)
MAST1Microtubule associated serine/threonine kinase 1. (1568 aa)
PrkchProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
GRK4G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (574 aa)
CDC42BPGCDC42 binding protein kinase gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1490 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (366 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MASTLMicrotubule associated serine/threonine kinase like. (867 aa)
I3MGY8_ICTTRAGC-kinase C-terminal domain-containing protein. (107 aa)
STK38Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (465 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
PRKCZNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (413 aa)
LATS1Large tumor suppressor kinase 1. (1131 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1748 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (690 aa)
MAST3Microtubule associated serine/threonine kinase 3. (1324 aa)
Sgk1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (454 aa)
GRK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (564 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1798 aa)
PrkxUncharacterized protein. (330 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
Grk7Rhodopsin kinase GRK7; Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO). (548 aa)
LATS2Large tumor suppressor kinase 2. (1060 aa)
Rps6kb1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
I3NC46_ICTTRNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (397 aa)
RPS6KA4Ribosomal protein S6 kinase. (800 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PKN1Protein kinase N1. (947 aa)
PKN3Protein kinase N3. (911 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
RPS6KA5Ribosomal protein S6 kinase. (859 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
MAST4Microtubule associated serine/threonine kinase family member 4. (2463 aa)
RPS6KA6Ribosomal protein S6 kinase. (830 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1386 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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