STRINGSTRING
LCK LCK RYK RYK ERBB4 ERBB4 FGFR4 FGFR4 BLK BLK FER FER KIT KIT INSR INSR ROR2 ROR2 RET RET ALK ALK FLT3 FLT3 EPHA4 EPHA4 EPHA2 EPHA2 TYK2 TYK2 ERBB2 ERBB2 FGFR2 FGFR2 MST1R MST1R BTK BTK HCK HCK EPHA1 EPHA1 TIE1 TIE1 SYK SYK MERTK MERTK BMX BMX JAK2 JAK2 EGFR EGFR FYN FYN TNK1 TNK1 PTK6 PTK6 SRMS SRMS NTRK1 NTRK1 LTK LTK NTRK2 NTRK2 ITK ITK FRK FRK ZAP70 ZAP70 PDGFRA PDGFRA IGF1R IGF1R DDR2 DDR2 EPHA5 EPHA5 MATK MATK PTK7 PTK7 FES FES EPHB1 EPHB1 EPHA3 EPHA3 TYRO3 TYRO3 KDR KDR SRC SRC FGR FGR LOC101955809 LOC101955809 TXK TXK CSF1R CSF1R FLT1 FLT1 FLT4 FLT4 INSRR INSRR MET MET JAK1 JAK1 CSK CSK ABL2 ABL2 EPHA6 EPHA6 MAP3K11 MAP3K11 ROS1 ROS1 PDGFRB PDGFRB ERBB3 ERBB3 ABL1 ABL1 EPHB2 EPHB2 TNK2 TNK2 EPHB4 EPHB4 ROR1 ROR1 MUSK MUSK TEC TEC DDR1 DDR1 FGFR1 FGFR1 EPHA7 EPHA7 NTRK3 NTRK3 AXL AXL LYN LYN EPHA8 EPHA8 EPHB3 EPHB3 PTK2B PTK2B TEK TEK PTK2 PTK2 FGFR3 FGFR3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LCKTyrosine-protein kinase. (521 aa)
RYKReceptor like tyrosine kinase. (475 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
FGFR4Fibroblast growth factor receptor. (801 aa)
BLKTyrosine-protein kinase. (499 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
INSRTyrosine-protein kinase receptor. (1359 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (910 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1112 aa)
ALKTyrosine-protein kinase receptor. (1612 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (985 aa)
EPHA4EPH receptor A4. (986 aa)
EPHA2EPH receptor A2. (923 aa)
TYK2Tyrosine-protein kinase. (1194 aa)
ERBB2Receptor protein-tyrosine kinase. (1256 aa)
FGFR2Fibroblast growth factor receptor. (823 aa)
MST1RMacrophage stimulating 1 receptor. (1382 aa)
BTKTyrosine-protein kinase. (659 aa)
HCKTyrosine-protein kinase. (502 aa)
EPHA1EPH receptor A1. (978 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1139 aa)
SYKTyrosine-protein kinase. (626 aa)
MERTKMER proto-oncogene, tyrosine kinase. (982 aa)
BMXTyrosine-protein kinase. (655 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
EGFRReceptor protein-tyrosine kinase. (1192 aa)
FYNTyrosine-protein kinase. (537 aa)
TNK1Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (662 aa)
PTK6Tyrosine-protein kinase. (450 aa)
SRMSTyrosine-protein kinase. (534 aa)
NTRK1Tyrosine-protein kinase receptor. (799 aa)
LTKTyrosine-protein kinase receptor. (576 aa)
NTRK2Tyrosine-protein kinase receptor. (821 aa)
ITKTyrosine-protein kinase. (620 aa)
FRKTyrosine-protein kinase. (511 aa)
ZAP70Tyrosine-protein kinase. (608 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
IGF1RTyrosine-protein kinase receptor. (1368 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
EPHA5EPH receptor A5. (1039 aa)
MATKTyrosine-protein kinase. (466 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1063 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
EPHB1EPH receptor B1. (984 aa)
EPHA3EPH receptor A3. (984 aa)
TYRO3TYRO3 protein tyrosine kinase. (890 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1345 aa)
SRCTyrosine-protein kinase. (541 aa)
FGRTyrosine-protein kinase. (527 aa)
LOC101955809Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1335 aa)
TXKTyrosine-protein kinase. (526 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (975 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1333 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1363 aa)
INSRRTyrosine-protein kinase receptor. (1279 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1380 aa)
JAK1Tyrosine-protein kinase. (1142 aa)
CSKTyrosine-protein kinase. (450 aa)
ABL2Tyrosine-protein kinase. (1142 aa)
EPHA6EPH receptor A6. (1128 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (848 aa)
ROS1Tyrosine-protein kinase receptor. (2333 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1112 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1248 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
EPHB2EPH receptor B2. (978 aa)
TNK2Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1055 aa)
EPHB4EPH receptor B4. (987 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (956 aa)
MUSKMuscle associated receptor tyrosine kinase. (884 aa)
TECTyrosine-protein kinase. (630 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (915 aa)
FGFR1Fibroblast growth factor receptor. (822 aa)
EPHA7EPH receptor A7. (998 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
AXLAXL receptor tyrosine kinase. (887 aa)
LYNTyrosine-protein kinase. (512 aa)
EPHA8EPH receptor A8. (1006 aa)
EPHB3EPH receptor B3. (996 aa)
PTK2BProtein tyrosine kinase 2 beta. (968 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1137 aa)
FGFR3Fibroblast growth factor receptor. (804 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.