STRINGSTRING
TYK2 TYK2 FRMD6 FRMD6 FRMD4B FRMD4B PTPN13 PTPN13 NF2 NF2 FARP2 FARP2 MYO15A MYO15A EPB41L5 EPB41L5 PTPN4 PTPN4 MYO7B MYO7B MSN MSN PTPN21 PTPN21 FRMD7 FRMD7 MYLIP MYLIP EPB41L4B EPB41L4B JAK3 JAK3 FRMD5 FRMD5 JAK2 JAK2 FARP1 FARP1 TLN1 TLN1 MYO10 MYO10 FRMD8 FRMD8 PLEKHH3 PLEKHH3 PLEKHH2 PLEKHH2 EPB41L2 EPB41L2 PLEKHH1 PLEKHH1 JAK1 JAK1 FRMPD3 FRMPD3 FRMD3 FRMD3 EPB41L4A EPB41L4A EPB41L3 EPB41L3 PTPN3 PTPN3 MYO7A MYO7A FRMPD1 FRMPD1 PTPN14 PTPN14 FRMPD2 FRMPD2 EPB41 EPB41 FRMPD4 FRMPD4 EZR EZR PTK2B PTK2B Krit1 Krit1 TLN2 TLN2 EPB41L1 EPB41L1 FRMD4A FRMD4A PTK2 PTK2 ENSSTOP00000031765 ENSSTOP00000031765 FRMD1 FRMD1 RDX RDX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TYK2Tyrosine-protein kinase. (1194 aa)
FRMD6FERM domain containing 6. (622 aa)
FRMD4BFERM domain containing 4B. (1017 aa)
PTPN13Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2483 aa)
NF2Neurofibromin 2. (596 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1063 aa)
MYO15AMyosin XVA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3517 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (732 aa)
PTPN4Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa)
MYO7BMyosin VIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2098 aa)
MSNMoesin. (577 aa)
PTPN21Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1108 aa)
FRMD7FERM domain containing 7. (707 aa)
MYLIPMyosin regulatory light chain interacting protein. (437 aa)
EPB41L4BErythrocyte membrane protein band 4.1 like 4B. (838 aa)
JAK3Tyrosine-protein kinase. (1042 aa)
FRMD5FERM domain containing 5. (570 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
FARP1FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1048 aa)
TLN1Talin 1. (2541 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2048 aa)
FRMD8FERM domain containing 8. (445 aa)
PLEKHH3Pleckstrin homology, MyTH4 and FERM domain containing H3. (791 aa)
PLEKHH2Pleckstrin homology, MyTH4 and FERM domain containing H2. (1491 aa)
EPB41L2Erythrocyte membrane protein band 4.1 like 2. (987 aa)
PLEKHH1Pleckstrin homology, MyTH4 and FERM domain containing H1. (1358 aa)
JAK1Tyrosine-protein kinase. (1142 aa)
FRMPD3FERM and PDZ domain containing 3. (1768 aa)
FRMD3FERM domain containing 3. (596 aa)
EPB41L4AErythrocyte membrane protein band 4.1 like 4A. (686 aa)
EPB41L3Erythrocyte membrane protein band 4.1 like 3. (940 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (882 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2215 aa)
FRMPD1FERM and PDZ domain containing 1. (1566 aa)
PTPN14Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1186 aa)
FRMPD2FERM and PDZ domain containing 2. (1297 aa)
EPB41Erythrocyte membrane protein band 4.1. (859 aa)
FRMPD4FERM and PDZ domain containing 4. (1322 aa)
EZREzrin. (604 aa)
PTK2BProtein tyrosine kinase 2 beta. (968 aa)
Krit1Uncharacterized protein. (736 aa)
TLN2Talin 2. (2542 aa)
EPB41L1Erythrocyte membrane protein band 4.1 like 1. (1606 aa)
FRMD4AFERM domain containing 4A. (1055 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1137 aa)
ENSSTOP00000031765Uncharacterized protein. (515 aa)
FRMD1FERM domain containing 1. (545 aa)
RDXRadixin. (583 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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