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| | LSM8 | U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa) |
| | ENO2 | Enolase 2. (434 aa) |
| | ENSSTOP00000027114 | Uncharacterized protein. (91 aa) |
| | C1D | C1D nuclear receptor corepressor. (141 aa) |
| | EXOSC10 | Exosome component 10. (886 aa) |
| | ENSSTOP00000028039 | Uncharacterized protein. (529 aa) |
| | CCT7 | T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (541 aa) |
| | CCT4 | T-complex protein 1 subunit delta. (539 aa) |
| | LOC101973964 | Uncharacterized protein. (321 aa) |
| | EXOSC1 | Exosome component 1. (195 aa) |
| | ZCCHC9 | Zinc finger CCHC-type containing 9. (268 aa) |
| | LSM3 | U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa) |
| | LSM8-2 | U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (108 aa) |
| | ENSSTOP00000029275 | ECR1_N domain-containing protein. (121 aa) |
| | PABPC4 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (644 aa) |
| | DHX30 | DExH-box helicase 30. (1235 aa) |
| | LSM5 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (89 aa) |
| | LOC101957349 | Uncharacterized protein. (247 aa) |
| | EDC3 | Enhancer of mRNA decapping 3. (508 aa) |
| | EXOSC2 | Exosome component 2. (293 aa) |
| | Lsm5 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa) |
| | PATL2 | PAT1 homolog 2. (540 aa) |
| | PAN2 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1120 aa) |
| | CNOT1 | CCR4-NOT transcription complex subunit 1. (2376 aa) |
| | LSM7 | LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (105 aa) |
| | CNBP | CCHC-type zinc finger nucleic acid binding protein. (177 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (631 aa) |
| | DIS3 | DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa) |
| | XRN2 | 5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (950 aa) |
| | ENO3 | Enolase 3. (434 aa) |
| | TMEM87A | Transmembrane protein 87A. (560 aa) |
| | I3LY53_ICTTR | Uncharacterized protein. (200 aa) |
| | CCT3 | T-complex protein 1 subunit gamma. (545 aa) |
| | PFKM | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa) |
| | LOC101974202 | ANK_REP_REGION domain-containing protein. (2485 aa) |
| | SLC30A6 | Solute carrier family 30 member 6. (461 aa) |
| | DPH2 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (489 aa) |
| | EXOSC4 | Exosome component 4. (246 aa) |
| | ENO4 | Enolase 4. (620 aa) |
| | LSM6 | LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa) |
| | CNOT6 | CCR4-NOT transcription complex subunit 6. (557 aa) |
| | EDC4 | Enhancer of mRNA decapping 4. (1405 aa) |
| | PABPC1L | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (614 aa) |
| | DHX36 | DEAH-box helicase 36. (1000 aa) |
| | DHX57 | DExH-box helicase 57. (1386 aa) |
| | TENT4A | Terminal nucleotidyltransferase 4A. (542 aa) |
| | CCT5 | Chaperonin containing TCP1 subunit 5. (541 aa) |
| | DCP1A | Decapping mRNA 1A. (582 aa) |
| | PLXDC2 | Plexin domain containing 2. (529 aa) |
| | PPIB | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa) |
| | SLC30A7 | Solute carrier family 30 member 7. (376 aa) |
| | PNLDC1 | PARN like, ribonuclease domain containing 1. (531 aa) |
| | DIS3L2 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (872 aa) |
| | I3M6L6_ICTTR | Uncharacterized protein. (104 aa) |
| | EXOSC7 | Exosome component 7. (291 aa) |
| | PFKP | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (791 aa) |
| | PPIC | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (211 aa) |
| | Tob1 | Uncharacterized protein. (345 aa) |
| | WRAP73 | WD repeat containing, antisense to TP73. (460 aa) |
| | PARN | Poly(A)-specific ribonuclease. (634 aa) |
| | WDR61 | WD repeat domain 61. (305 aa) |
| | PDE12 | Phosphodiesterase 12. (609 aa) |
| | EXOSC9 | Exosome component 9. (439 aa) |
| | HSPA9 | Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa) |
| | DIS3L | DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1007 aa) |
| | BTG4 | BTG anti-proliferation factor 4. (230 aa) |
| | PAN3 | PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (881 aa) |
| | IPO7 | Importin 7. (1038 aa) |
| | EXOSC3 | Exosome component 3. (275 aa) |
| | DCPS | Decapping enzyme, scavenger. (335 aa) |
| | Btg3 | Uncharacterized protein. (252 aa) |
| | SLC30A5 | Solute carrier family 30 member 5. (766 aa) |
| | CCT6A | Chaperonin containing TCP1 subunit 6A. (531 aa) |
| | TOE1 | Target of EGR1, exonuclease. (508 aa) |
| | DHX29 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1371 aa) |
| | MTREX | Mtr4 exosome RNA helicase. (1042 aa) |
| | ERMARD | ER membrane associated RNA degradation. (667 aa) |
| | NUDT16 | Nudix hydrolase 16. (195 aa) |
| | ENO1 | Enolase 1. (434 aa) |
| | UFSP2 | UFM1 specific peptidase 2. (463 aa) |
| | LSM2 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa) |
| | DCP2 | Decapping mRNA 2. (419 aa) |
| | XRN1 | 5'-3' exoribonuclease 1. (1731 aa) |
| | WRN | WRN RecQ like helicase. (1448 aa) |
| | PATL1 | PAT1 homolog 1, processing body mRNA decay factor. (764 aa) |
| | CCT2 | Chaperonin containing TCP1 subunit 2. (535 aa) |
| | TTC37 | Tetratricopeptide repeat domain 37. (1564 aa) |
| | MKKS | McKusick-Kaufman syndrome. (570 aa) |
| | DDX6 | DEAD-box helicase 6; Belongs to the DEAD box helicase family. (483 aa) |
| | SKIV2L | Ski2 like RNA helicase. (1246 aa) |
| | NOCT | Nocturnin. (367 aa) |
| | CNOT9 | CCR4-NOT transcription complex subunit 9. (299 aa) |
| | CWH43 | Cell wall biogenesis 43 C-terminal homolog. (699 aa) |
| | CNOT10 | CCR4-NOT transcription complex subunit 10. (744 aa) |
| | CNOT6L | CCR4-NOT transcription complex subunit 6 like. (550 aa) |
| | ZCCHC2 | Zinc finger CCHC-type containing 2. (916 aa) |
| | I3MPV3_ICTTR | Importin N-terminal domain-containing protein. (361 aa) |
| | Tob2 | Uncharacterized protein. (345 aa) |
| | LRRC27 | Leucine rich repeat containing 27. (517 aa) |
| | NUDT18 | Nudix hydrolase 18; Belongs to the Nudix hydrolase family. (323 aa) |
| | LSM1 | U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (82 aa) |
| | HELZ2 | Helicase with zinc finger 2. (2881 aa) |
| | NAXE | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (281 aa) |
| | LOC101978573 | Uncharacterized protein. (200 aa) |
| | Cbwd1 | CobW C-terminal domain-containing protein. (395 aa) |
| | ZCCHC13 | Zinc finger CCHC-type containing 13. (170 aa) |
| | ICE1 | Interactor of little elongation complex ELL subunit 1. (2264 aa) |
| | UFSP1 | UFM1 specific peptidase 1 (inactive). (212 aa) |
| | BBS10 | Bardet-Biedl syndrome 10. (723 aa) |
| | CNOT3 | CCR4-NOT transcription complex subunit 3. (751 aa) |
| | Mphosph6 | Uncharacterized protein. (161 aa) |
| | PABPC3 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (607 aa) |
| | NUDT6 | Nudix hydrolase 6; Belongs to the Nudix hydrolase family. (271 aa) |
| | I3N2F3_ICTTR | Uncharacterized protein. (220 aa) |
| | VPS72 | Vacuolar protein sorting 72 homolog. (364 aa) |
| | PPP4R2 | Protein phosphatase 4 regulatory subunit 2. (455 aa) |
| | LOC101978280 | Polyadenylate-binding protein 1-like 2. (200 aa) |
| | DCP1B | Decapping mRNA 1B. (618 aa) |
| | I3N7W8_ICTTR | Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (202 aa) |
| | PNPT1 | Polyribonucleotide nucleotidyltransferase 1. (784 aa) |
| | PABPC4L | Poly(A) binding protein cytoplasmic 4 like. (372 aa) |
| | TMEM87B | Transmembrane protein 87B. (498 aa) |
| | DPH1 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (435 aa) |
| | TMEM176B | Transmembrane protein 176B. (269 aa) |
| | C19orf54 | Chromosome 19 open reading frame 54. (350 aa) |
| | EXOSC5 | Exosome component 5. (235 aa) |
| | PFKL | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa) |
| | EXOSC6 | Exosome component 6. (272 aa) |
| | DDX60 | DExD/H-box helicase 60. (1465 aa) |
| | PLXDC1 | Plexin domain containing 1. (471 aa) |
| | CCT6B | Chaperonin containing TCP1 subunit 6B. (531 aa) |
| | BTG2 | BTG anti-proliferation factor 2. (158 aa) |
| | PAM | Peptidylglycine alpha-amidating monooxygenase. (979 aa) |
| | Lsm4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa) |
| | CNOT4 | CCR4-NOT transcription complex subunit 4. (710 aa) |
| | Tcp1 | Uncharacterized protein. (556 aa) |
| | ENSSTOP00000024694 | Uncharacterized protein. (158 aa) |
| | CNOT2 | CCR4-NOT transcription complex subunit 2. (540 aa) |
| | ENSSTOP00000025355 | Uncharacterized protein. (127 aa) |
| | ENSSTOP00000025407 | Uncharacterized protein. (163 aa) |
| | LOC101962934 | Anti_prolifrtn domain-containing protein. (137 aa) |
| | Exosc8 | RNase_PH domain-containing protein. (89 aa) |
| | LOC101961139 | Anti_prolifrtn domain-containing protein. (290 aa) |
| | ZCCHC7 | Zinc finger CCHC-type containing 7. (582 aa) |
| | CNOT7 | Uncharacterized protein. (285 aa) |
