(135 nodes) Oocyte meiosis network (Ictidomys tridecemlineatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CAMK2A	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
	LOC101963097	Uncharacterized protein. (243 aa)
	CAMK2B	Calcium/calmodulin dependent protein kinase II beta. (666 aa)
	CDC26	Cell division cycle 26. (85 aa)
	MAPK3	Mitogen-activated protein kinase. (361 aa)
	PPP2R1A	Protein phosphatase 2 scaffold subunit Aalpha. (589 aa)
	SMC1B	Structural maintenance of chromosomes protein. (1237 aa)
	Ccnb2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa)
	REC8	REC8 meiotic recombination protein. (594 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (334 aa)
	Cpeb2	RRM domain-containing protein. (262 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
	SGO1	Shugoshin 1. (530 aa)
	ANAPC1	Anaphase promoting complex subunit 1. (1891 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	CCNE2	Cyclin E2; Belongs to the cyclin family. (404 aa)
	I3M4Y3_ICTTR	Protein kinase domain-containing protein. (142 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (955 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	Ywhae	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (733 aa)
	AURKB	Aurora kinase B; Belongs to the protein kinase superfamily. (345 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1233 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	PTRHD1	Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
	SMC3	Structural maintenance of chromosomes 3. (995 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (523 aa)
	ENSSTOP00000032237	Uncharacterized protein; Belongs to the calmodulin family. (148 aa)
	ANAPC2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (830 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (744 aa)
	RPS6KA6	Ribosomal protein S6 kinase. (830 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	ENSSTOP00000030497	SER_THR_PHOSPHATASE domain-containing protein. (298 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
	ESPL1	Extra spindle pole bodies like 1, separase. (2071 aa)
	ENSSTOP00000029937	Uncharacterized protein; Belongs to the calmodulin family. (67 aa)
	IGF1	Insulin like growth factor 1. (166 aa)
	Ywhaq	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (125 aa)
	CCNB1	Cyclin B1; Belongs to the cyclin family. (429 aa)
	ENSSTOP00000029069	EF-hand domain-containing protein. (222 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	CDK2	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
	ENSSTOP00000028717	RING-type domain-containing protein. (95 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
	ENSSTOP00000028494	RRM domain-containing protein. (160 aa)
	PPP2R5C	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
	CDC16	Cell division cycle 16. (614 aa)
	ENSSTOP00000027631	SER_THR_PHOSPHATASE domain-containing protein. (235 aa)
	TMEM82	Transmembrane protein 82. (380 aa)
	Ppp2cb	Serine/threonine-protein phosphatase. (274 aa)
	CPEB4	Cytoplasmic polyadenylation element binding protein 4. (729 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2748 aa)
	ENSSTOP00000027094	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (208 aa)
	CALM3	Calmodulin 3. (149 aa)
	ENSSTOP00000026851	Uncharacterized protein. (61 aa)
	PPP2R1B	Protein phosphatase 2 scaffold subunit Abeta. (658 aa)
	ENSSTOP00000026345	Protein kinase domain-containing protein. (386 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
	ENSSTOP00000025973	14_3_3 domain-containing protein. (119 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
	CDC20B	Cell division cycle 20B. (523 aa)
	LOC101974796	Uncharacterized protein; Belongs to the cyclin family. (387 aa)
	PKMYT1	Protein kinase, membrane associated tyrosine/threonine 1; Belongs to the protein kinase superfamily. (489 aa)
	CAMK2G	Calcium/calmodulin dependent protein kinase II gamma. (512 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
	LOC101965246	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
	MAPK13	Mitogen-activated protein kinase. (326 aa)
	CALM2	Calmodulin 2; Belongs to the calmodulin family. (149 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	FBXW11	F-box and WD repeat domain containing 11. (553 aa)
	CAMK2D	Calcium/calmodulin dependent protein kinase II delta. (514 aa)
	MAD2L1	Mitotic arrest deficient 2 like 1. (205 aa)
	LOC101967492	Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
	LOC101961406	Uncharacterized protein. (172 aa)
	PPP2R5B	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
	FBXO43	F-box protein 43. (706 aa)
	Anapc13	Uncharacterized protein. (74 aa)
	CPEB3	Cytoplasmic polyadenylation element binding protein 3. (697 aa)
	PPP2R5D	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (603 aa)
	YWHAH	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
	SPDYA	Speedy/RINGO cell cycle regulator family member A. (312 aa)
	PGR	Progesterone receptor. (932 aa)
	ARSI	Arylsulfatase family member I. (572 aa)
	Ywhaz	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
	I3N110_ICTTR	RING-type domain-containing protein. (147 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (318 aa)
	Cpeb1	Uncharacterized protein. (566 aa)
	Ins	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	PPP2R5E	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
	Pttg1	Uncharacterized protein. (118 aa)
	CALML6	Calmodulin like 6. (172 aa)
	MOS	MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (349 aa)
	Anapc11	RING-type domain-containing protein. (84 aa)
	AR	Androgen receptor. (884 aa)
	FBXO5	F-box protein 5. (450 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (487 aa)
	Ppp3r1	Uncharacterized protein. (169 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (148 aa)
	ANAPC4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa)
	Rbx1	RING-type domain-containing protein. (108 aa)
	CALML4	Calmodulin like 4. (153 aa)
	MAPK11	Mitogen-activated protein kinase. (325 aa)
	MAPK12	Mitogen-activated protein kinase. (325 aa)
	MAPK1	Mitogen-activated protein kinase. (331 aa)
	YWHAG	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
	PPP2R5A	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
	SLK	STE20 like kinase. (1242 aa)
	PLK1	Serine/threonine-protein kinase PLK. (601 aa)
	ANAPC7	Anaphase promoting complex subunit 7. (581 aa)
	Aurka	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (363 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (511 aa)
	STAG3	Stromal antigen 3. (1182 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1368 aa)
	PLCZ1	Phosphoinositide phospholipase C. (594 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	RPS6KA3	Ribosomal protein S6 kinase. (740 aa)
	EFCAB3	EF-hand calcium binding domain 3. (432 aa)
	MTRF1L	Mitochondrial translational release factor 1 like. (364 aa)
	MAD2L2	Mitotic arrest deficient 2 like 2. (211 aa)
	ANAPC5	Anaphase promoting complex subunit 5. (691 aa)
	CDC20	Cell division cycle 20. (499 aa)
	CCNE1	Cyclin E1; Belongs to the cyclin family. (410 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
	CALML3	Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
	CDC27	Cell division cycle 27. (848 aa)
	ANAPC10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
	CDC23	Cell division cycle 23. (599 aa)
	CDK3	Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (304 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSSTOP00000007821	ENSSTOP00000004376	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.599
ADCY1	ADCY3	ENSSTOP00000007821	ENSSTOP00000005426	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.843
ADCY1	ADCY4	ENSSTOP00000007821	ENSSTOP00000002179	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.587
ADCY1	ADCY5	ENSSTOP00000007821	ENSSTOP00000000037	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.580
ADCY1	ADCY6	ENSSTOP00000007821	ENSSTOP00000003745	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.580
ADCY1	ADCY7	ENSSTOP00000007821	ENSSTOP00000028572	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.619
ADCY1	ADCY8	ENSSTOP00000007821	ENSSTOP00000030610	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.843
ADCY1	ADCY9	ENSSTOP00000007821	ENSSTOP00000004525	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.833
ADCY1	CALM1	ENSSTOP00000007821	ENSSTOP00000014633	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 1; Belongs to the calmodulin family.	0.674
ADCY1	CALM2	ENSSTOP00000007821	ENSSTOP00000023145	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 2; Belongs to the calmodulin family.	0.674
ADCY1	CALM3	ENSSTOP00000007821	ENSSTOP00000027029	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 3.	0.674
ADCY1	CALML3	ENSSTOP00000007821	ENSSTOP00000007300	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 3; Belongs to the calmodulin family.	0.883
ADCY1	CALML4	ENSSTOP00000007821	ENSSTOP00000013905	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 4.	0.867
ADCY1	CALML6	ENSSTOP00000007821	ENSSTOP00000016185	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 6.	0.901
ADCY1	CAMK2A	ENSSTOP00000007821	ENSSTOP00000008004	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily.	0.862
ADCY1	CAMK2B	ENSSTOP00000007821	ENSSTOP00000000405	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II beta.	0.865
ADCY1	CAMK2D	ENSSTOP00000007821	ENSSTOP00000022466	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II delta.	0.861
ADCY1	CAMK2G	ENSSTOP00000007821	ENSSTOP00000024253	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II gamma.	0.847
ADCY1	EFCAB3	ENSSTOP00000007821	ENSSTOP00000009227	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	EF-hand calcium binding domain 3.	0.597
ADCY1	ENSSTOP00000029069	ENSSTOP00000007821	ENSSTOP00000029069	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	EF-hand domain-containing protein.	0.597