STRINGSTRING
ERAS ERAS EFNA2 EFNA2 SEMA6B SEMA6B CAMK2D CAMK2D NTNG2 NTNG2 ABLIM3 ABLIM3 ABLIM2 ABLIM2 GSK3B GSK3B SEMA6A SEMA6A CAMK2G CAMK2G SEMA3B SEMA3B ENAH ENAH LOC101968118 LOC101968118 TRPC5 TRPC5 EPHB6 EPHB6 PIK3R1 PIK3R1 ENSSTOP00000026119 ENSSTOP00000026119 EPHB2 EPHB2 PAK3 PAK3 EPHB4 EPHB4 ABLIM1 ABLIM1 SRGAP3 SRGAP3 ENSSTOP00000027772 ENSSTOP00000027772 LOC101975023 LOC101975023 EPHA7 EPHA7 Srgap2 Srgap2 SEMA3C SEMA3C HRAS HRAS PLXNB3 PLXNB3 TRPC4 TRPC4 NFATC2 NFATC2 PDK1 PDK1 Pik3r3 Pik3r3 TRPC1 TRPC1 Pik3cd Pik3cd Cfl1 Cfl1 ENSSTOP00000029727 ENSSTOP00000029727 EPHA8 EPHA8 EPHB3 EPHB3 EFNB3 EFNB3 EFNA1 EFNA1 SEMA4A SEMA4A PAK6 PAK6 SSH3 SSH3 RGMA RGMA ENSSTOP00000031001 ENSSTOP00000031001 Csde1 Csde1 ROBO2 ROBO2 RYK RYK I3LWC1_ICTTR I3LWC1_ICTTR SEMA3G SEMA3G PAK5 PAK5 CAMK2B CAMK2B ROBO1 ROBO1 SEMA6C SEMA6C RASA1 RASA1 NTN1 NTN1 PLXNC1 PLXNC1 Cdc42 Cdc42 WNT4 WNT4 MAPK3 MAPK3 NCK2 NCK2 SEMA4D SEMA4D SEMA4F SEMA4F PIK3CB PIK3CB Cfl2 Cfl2 MYL9 MYL9 RRAS RRAS NCK1 NCK1 Pik3r2 Pik3r2 BMPR2 BMPR2 SEMA5A SEMA5A NTN4 NTN4 NFATC4 NFATC4 EPHA4 EPHA4 TRPC6 TRPC6 EPHA2 EPHA2 PLXNA3 PLXNA3 DCC DCC BOC BOC UNC5A UNC5A DPYSL2 DPYSL2 RND1 RND1 Rhoa Rhoa EFNA5 EFNA5 NTNG1 NTNG1 EPHA1 EPHA1 Epha10 Epha10 PLCG2 PLCG2 LOC101966943 LOC101966943 MYL12B MYL12B CXCL12 CXCL12 SEMA3D SEMA3D CXCR4 CXCR4 SEMA4C SEMA4C RAC1 RAC1 EFNB2 EFNB2 FYN FYN PTK6 PTK6 SRMS SRMS Rgs3 Rgs3 PAK2 PAK2 GNAI3 GNAI3 ADAM15 ADAM15 EFNA3 EFNA3 CAMK2A CAMK2A SEMA4G SEMA4G PARD6B PARD6B KRAS KRAS LOC101962660 LOC101962660 DPYSL5 DPYSL5 SEMA4B SEMA4B SEMA5B SEMA5B SEMA3E SEMA3E SLIT1 SLIT1 FZD3 FZD3 PLXNA4 PLXNA4 SMO SMO SSH1 SSH1 ILK ILK PLCG1 PLCG1 EPHA5 EPHA5 PPP3CA PPP3CA GNAI1 GNAI1 NEO1 NEO1 WNT5B WNT5B PLXNB1 PLXNB1 BMP7 BMP7 PAK1 PAK1 LIMK1 LIMK1 PIK3CA PIK3CA ITGB1 ITGB1 NRP1 NRP1 RHOD RHOD SLIT3 SLIT3 RAC3 RAC3 PLXNA2 PLXNA2 TRPC3 TRPC3 MAPK1 MAPK1 FES FES EPHB1 EPHB1 EPHA3 EPHA3 PARD6G PARD6G BMPR1B BMPR1B UNC5C UNC5C PARD3 PARD3 SEMA6D SEMA6D ARHGEF12 ARHGEF12 SEMA3F SEMA3F GNAI2 GNAI2 ROBO3 ROBO3 Ppp3r1 Ppp3r1 LOC101965906 LOC101965906 PPP3CC PPP3CC SHH SHH LDAH LDAH NFATC3 NFATC3 NRAS NRAS PLXNB2 PLXNB2 SSH2 SSH2 MYL5 MYL5 PLXNA1 PLXNA1 LRRC4 LRRC4 RAC2 RAC2 NTN3 NTN3 SEMA7A SEMA7A LRRC4C LRRC4C PARD6A PARD6A UNC5B UNC5B EFNA4 EFNA4 ARSI ARSI LOC101959358 LOC101959358 GDF7 GDF7 MET MET EFNB1 EFNB1 I3N4S4_ICTTR I3N4S4_ICTTR ROCK1 ROCK1 Rhoc Rhoc PTPN11 PTPN11 I3N6Q6_ICTTR I3N6Q6_ICTTR LOC101969460 LOC101969460 NGEF NGEF Pak4 Pak4 WNT5A WNT5A LIMK2 LIMK2 CCDC125 CCDC125 EPHA6 EPHA6 PTCH1 PTCH1 PTK2 PTK2 LOC101966144 LOC101966144 SRGAP1 SRGAP1 ENSSTOP00000031499 ENSSTOP00000031499 CDK5 CDK5 TRPC7 TRPC7 L1CAM L1CAM ROCK2 ROCK2 SLIT2 SLIT2 PPP3CB PPP3CB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERASES cell expressed Ras. (227 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (197 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (801 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (514 aa)
NTNG2Netrin G2. (590 aa)
ABLIM3Actin binding LIM protein family member 3. (683 aa)
ABLIM2Actin binding LIM protein family member 2. (630 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (512 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (778 aa)
ENAHENAH actin regulator. (784 aa)
LOC101968118Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (932 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
EPHB6EPH receptor B6. (1016 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSSTOP00000026119Uncharacterized protein. (143 aa)
EPHB2EPH receptor B2. (978 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
EPHB4EPH receptor B4. (987 aa)
ABLIM1Actin binding LIM protein 1. (784 aa)
SRGAP3SLIT-ROBO Rho GTPase activating protein 3. (1104 aa)
ENSSTOP00000027772Fibronectin type-III domain-containing protein. (157 aa)
LOC101975023CSD_1 domain-containing protein. (729 aa)
EPHA7EPH receptor A7. (998 aa)
Srgap2Uncharacterized protein. (1071 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PLXNB3Plexin B3. (1954 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
NFATC2Nuclear factor of activated T cells 2. (844 aa)
PDK1Protein-serine/threonine kinase. (436 aa)
Pik3r3Uncharacterized protein. (461 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (748 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Cfl1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (203 aa)
ENSSTOP00000029727ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (152 aa)
EPHA8EPH receptor A8. (1006 aa)
EPHB3EPH receptor B3. (996 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (346 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (758 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
SSH3Slingshot protein phosphatase 3. (648 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (450 aa)
ENSSTOP00000031001Uncharacterized protein. (178 aa)
Csde1Uncharacterized protein. (555 aa)
ROBO2Roundabout guidance receptor 2. (1468 aa)
RYKReceptor like tyrosine kinase. (475 aa)
I3LWC1_ICTTRIg-like domain-containing protein. (512 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (773 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
ROBO1Roundabout guidance receptor 1. (1587 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (866 aa)
RASA1RAS p21 protein activator 1. (1030 aa)
NTN1Netrin 1. (596 aa)
PLXNC1Plexin C1. (1550 aa)
Cdc42Uncharacterized protein. (191 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa)
MAPK3Mitogen-activated protein kinase. (361 aa)
NCK2Cytoplasmic protein. (380 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (747 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
Cfl2ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (167 aa)
MYL9Myosin light chain 9. (172 aa)
RRASRAS related. (218 aa)
NCK1Cytoplasmic protein. (377 aa)
Pik3r2Uncharacterized protein. (724 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
SEMA5ASemaphorin 5A. (1074 aa)
NTN4Netrin 4. (627 aa)
NFATC4Nuclear factor of activated T cells 4. (890 aa)
EPHA4EPH receptor A4. (986 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (903 aa)
EPHA2EPH receptor A2. (923 aa)
PLXNA3Plexin A3. (1872 aa)
DCCDCC netrin 1 receptor. (1447 aa)
BOCBOC cell adhesion associated, oncogene regulated. (1115 aa)
UNC5AUnc-5 netrin receptor A. (891 aa)
DPYSL2Dihydropyrimidinase like 2. (677 aa)
RND1Rho family GTPase 1. (232 aa)
RhoaRas homolog family member A. (193 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (186 aa)
NTNG1Netrin G1. (543 aa)
EPHA1EPH receptor A1. (978 aa)
Epha10Eph LBD domain-containing protein. (293 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
LOC101966943Uncharacterized protein. (172 aa)
MYL12BMyosin light chain 12B. (172 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (735 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (352 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (831 aa)
RAC1Rac family small GTPase 1. (211 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (334 aa)
FYNTyrosine-protein kinase. (537 aa)
PTK6Tyrosine-protein kinase. (450 aa)
SRMSTyrosine-protein kinase. (534 aa)
Rgs3Uncharacterized protein. (610 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ADAM15ADAM metallopeptidase domain 15. (837 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (210 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (839 aa)
PARD6BPar-6 family cell polarity regulator beta. (350 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
LOC101962660Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (824 aa)
DPYSL5Dihydropyrimidinase like 5. (564 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (823 aa)
SEMA5BSemaphorin 5B. (1093 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (721 aa)
SLIT1Slit guidance ligand 1. (1525 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
PLXNA4Plexin A4. (1893 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
SSH1Slingshot protein phosphatase 1. (1016 aa)
ILKIntegrin linked kinase. (452 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
EPHA5EPH receptor A5. (1039 aa)
PPP3CASerine/threonine-protein phosphatase. (511 aa)
GNAI1G protein subunit alpha i1. (354 aa)
NEO1Neogenin 1. (1440 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (400 aa)
PLXNB1Plexin B1. (2119 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
LIMK1LIM domain kinase 1. (628 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
RHODRas homolog family member D. (185 aa)
SLIT3Slit guidance ligand 3. (1385 aa)
RAC3Rac family small GTPase 3. (185 aa)
PLXNA2Plexin A2. (1795 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (848 aa)
MAPK1Mitogen-activated protein kinase. (331 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
EPHB1EPH receptor B1. (984 aa)
EPHA3EPH receptor A3. (984 aa)
PARD6GPar-6 family cell polarity regulator gamma. (383 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
UNC5CUnc-5 netrin receptor C. (916 aa)
PARD3Par-3 family cell polarity regulator. (1296 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1061 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1518 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
GNAI2G protein subunit alpha i2. (355 aa)
ROBO3Roundabout guidance receptor 3. (1343 aa)
Ppp3r1Uncharacterized protein. (169 aa)
LOC101965906Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (970 aa)
PPP3CCSerine/threonine-protein phosphatase. (487 aa)
SHHSonic hedgehog signaling molecule. (370 aa)
LDAHLipid droplet associated hydrolase. (325 aa)
NFATC3Nuclear factor of activated T cells 3. (1075 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PLXNB2Plexin B2. (1842 aa)
SSH2Slingshot protein phosphatase 2. (1423 aa)
MYL5Myosin light chain 5. (172 aa)
PLXNA1Plexin A1. (1878 aa)
LRRC4Leucine rich repeat containing 4. (651 aa)
RAC2Rac family small GTPase 2. (192 aa)
NTN3Netrin 3. (471 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (664 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
UNC5BUnc-5 netrin receptor B. (946 aa)
EFNA4Ephrin A4; Belongs to the ephrin family. (204 aa)
ARSIArylsulfatase family member I. (572 aa)
LOC101959358Uncharacterized protein. (193 aa)
GDF7Growth differentiation factor 7. (445 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1380 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (345 aa)
I3N4S4_ICTTRUncharacterized protein. (162 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
RhocUncharacterized protein. (193 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
I3N6Q6_ICTTRADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (160 aa)
LOC101969460RGS domain-containing protein. (192 aa)
NGEFNeuronal guanine nucleotide exchange factor. (707 aa)
Pak4Protein kinase domain-containing protein. (240 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
LIMK2LIM domain kinase 2. (638 aa)
CCDC125Coiled-coil domain containing 125. (512 aa)
EPHA6EPH receptor A6. (1128 aa)
PTCH1Patched 1. (1450 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1137 aa)
LOC101966144Uncharacterized protein. (147 aa)
SRGAP1SLIT-ROBO Rho GTPase activating protein 1. (1085 aa)
ENSSTOP00000031499Uncharacterized protein. (157 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
L1CAML1 cell adhesion molecule. (1256 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1386 aa)
SLIT2Slit guidance ligand 2. (1559 aa)
PPP3CBSerine/threonine-protein phosphatase. (523 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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