STRINGSTRING
Pik3r2 Pik3r2 FGFR3 FGFR3 ACVR1C ACVR1C APC APC LOC101962293 LOC101962293 Csde1 Csde1 MEIS1 MEIS1 Inhba Inhba IGF1 IGF1 Pik3cd Pik3cd ENSSTOP00000029470 ENSSTOP00000029470 FZD7 FZD7 Pik3r3 Pik3r3 HRAS HRAS AKT1 AKT1 LOC101975023 LOC101975023 APC2 APC2 FGFR1 FGFR1 PIK3R1 PIK3R1 ENSSTOP00000026011 ENSSTOP00000026011 MEIS2 MEIS2 PCGF1 PCGF1 DVL3 DVL3 TBX3 TBX3 LOC101968118 LOC101968118 MAPK13 MAPK13 LOC101961346 LOC101961346 GSK3B GSK3B ZFHX3 ZFHX3 MAPK14 MAPK14 PCGF3 PCGF3 FZD2 FZD2 FZD8 FZD8 WNT7B WNT7B PRRX1 PRRX1 ESRRB ESRRB ONECUT1 ONECUT1 FZD9 FZD9 ID2 ID2 WNT3A WNT3A NFIL3 NFIL3 HOXA1 HOXA1 LHX5 LHX5 INHBE INHBE KAT6A KAT6A ERAS ERAS WNT11 WNT11 WNT5A WNT5A WNT3 WNT3 AXIN2 AXIN2 JAK1 JAK1 ZIC3 ZIC3 INHBB INHBB Onecut3 Onecut3 WNT7A WNT7A POU5F2 POU5F2 NEUROG1 NEUROG1 OTX1 OTX1 WNT10A WNT10A WNT8B WNT8B WNT9B WNT9B FZD5 FZD5 LHX1 LHX1 HAND1 HAND1 Nanog Nanog ACVR2A ACVR2A SMAD4 SMAD4 ID3 ID3 Pou5f1 Pou5f1 HOXB1 HOXB1 FZD10 FZD10 Fgf2 Fgf2 FZD4 FZD4 RIF1 RIF1 NRAS NRAS TCF7 TCF7 ZIC2 ZIC2 LOC101965906 LOC101965906 ONECUT2 ONECUT2 CTNNB1 CTNNB1 BMPR1A BMPR1A MYF5 MYF5 MAPK11 MAPK11 MAPK12 MAPK12 BMPR1B BMPR1B ACVR2B ACVR2B MAPK1 MAPK1 PCGF6 PCGF6 PCGF2 PCGF2 FZD1 FZD1 ISL1 ISL1 DVL1 DVL1 NODAL NODAL PIK3CA PIK3CA GRB2 GRB2 LIFR LIFR WNT5B WNT5B AXIN1 AXIN1 HOXD1 HOXD1 SMAD5 SMAD5 JARID2 JARID2 WNT2B WNT2B IGF1R IGF1R FZD3 FZD3 SOX2 SOX2 SMAD1 SMAD1 AKT3 AKT3 TCF3 TCF3 SMAD3 SMAD3 LOC101962660 LOC101962660 KRAS KRAS ESRRG ESRRG TBX2 TBX2 MAP2K1 MAP2K1 PCGF5 PCGF5 DVL2 DVL2 WNT9A WNT9A DUSP9 DUSP9 SKIL SKIL FZD6 FZD6 JAK3 JAK3 ID1 ID1 Rest Rest WNT8A WNT8A SMAD9 SMAD9 SETDB1 SETDB1 STAT3 STAT3 JAK2 JAK2 WNT6 WNT6 WNT16 WNT16 LIF LIF ISL2 ISL2 WNT2 WNT2 DLX5 DLX5 IL6ST IL6ST MYC MYC ACVR1 ACVR1 WNT10B WNT10B FGFR2 FGFR2 WNT1 WNT1 SMAD2 SMAD2 PAX6 PAX6 AKT2 AKT2 Map2k2 Map2k2 BMPR2 BMPR2 LOC101955676 LOC101955676 PIK3CB PIK3CB SMARCAD1 SMARCAD1 BMP4 BMP4 INHBC INHBC ZIC1 ZIC1 MAPK3 MAPK3 WNT4 WNT4 ACVR1B ACVR1B FGFR4 FGFR4 HESX1 HESX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pik3r2Uncharacterized protein. (724 aa)
FGFR3Fibroblast growth factor receptor. (804 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
APCAPC regulator of WNT signaling pathway. (2865 aa)
LOC101962293Left-right determination factor. (367 aa)
Csde1Uncharacterized protein. (555 aa)
MEIS1Meis homeobox 1. (465 aa)
InhbaTGF_BETA_2 domain-containing protein. (133 aa)
IGF1Insulin like growth factor 1. (166 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
ENSSTOP00000029470POU-specific domain-containing protein. (311 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (598 aa)
Pik3r3Uncharacterized protein. (461 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC101975023CSD_1 domain-containing protein. (729 aa)
APC2APC regulator of WNT signaling pathway 2. (2114 aa)
FGFR1Fibroblast growth factor receptor. (822 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSSTOP00000026011BHLH domain-containing protein. (102 aa)
MEIS2Meis homeobox 2. (470 aa)
PCGF1Polycomb group ring finger 1. (259 aa)
DVL3Dishevelled segment polarity protein 3. (717 aa)
TBX3T-box transcription factor 3. (744 aa)
LOC101968118Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (932 aa)
MAPK13Mitogen-activated protein kinase. (326 aa)
LOC101961346Left-right determination factor. (363 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
ZFHX3Zinc finger homeobox 3. (3696 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PCGF3Polycomb group ring finger 3. (241 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (556 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (470 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
PRRX1Paired related homeobox 1. (245 aa)
ESRRBEstrogen related receptor beta. (454 aa)
ONECUT1One cut domain family member. (465 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (552 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
NFIL3Nuclear factor, interleukin 3 regulated. (463 aa)
HOXA1Homeobox A1. (337 aa)
LHX5LIM homeobox 5. (402 aa)
INHBEInhibin subunit beta E. (349 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2017 aa)
ERASES cell expressed Ras. (227 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
AXIN2Axin 2. (840 aa)
JAK1Tyrosine-protein kinase. (1142 aa)
ZIC3Zic family member 3. (466 aa)
INHBBInhibin subunit beta B. (336 aa)
Onecut3One cut domain family member. (466 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (336 aa)
POU5F2POU domain protein. (335 aa)
NEUROG1Neurogenin 1. (244 aa)
OTX1Orthodenticle homeobox 1. (355 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
LHX1LIM homeobox 1. (406 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
NanogHomeobox domain-containing protein. (306 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
Pou5f1POU domain protein. (360 aa)
HOXB1Homeobox B1. (302 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
Fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (144 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
RIF1Replication timing regulatory factor 1. (2480 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
TCF7Transcription factor 7. (302 aa)
ZIC2Zic family member 2. (341 aa)
LOC101965906Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (970 aa)
ONECUT2One cut domain family member. (428 aa)
CTNNB1Catenin beta 1. (781 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MAPK11Mitogen-activated protein kinase. (325 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (527 aa)
MAPK1Mitogen-activated protein kinase. (331 aa)
PCGF6Polycomb group ring finger 6. (350 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (643 aa)
ISL1ISL LIM homeobox 1. (349 aa)
DVL1Dishevelled segment polarity protein 1. (696 aa)
NODALNodal growth differentiation factor. (350 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
LIFRLIF receptor subunit alpha. (1096 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (400 aa)
AXIN1Axin 1. (869 aa)
HOXD1Homeobox D1. (330 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1226 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (392 aa)
IGF1RTyrosine-protein kinase receptor. (1368 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
SOX2SRY-box transcription factor 2. (263 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
TCF3Transcription factor 3. (681 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
LOC101962660Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (824 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ESRRGEstrogen related receptor gamma. (458 aa)
TBX2T-box transcription factor 2. (712 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
PCGF5Polycomb group ring finger 5. (256 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (383 aa)
SKILSKI like proto-oncogene. (677 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (711 aa)
JAK3Tyrosine-protein kinase. (1042 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (151 aa)
RestUncharacterized protein. (328 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
SMAD9Mothers against decapentaplegic homolog. (452 aa)
SETDB1SET domain bifurcated histone lysine methyltransferase 1. (1317 aa)
STAT3Signal transducer and activator of transcription. (748 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
ISL2ISL LIM homeobox 2. (359 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
DLX5Distal-less homeobox 5. (289 aa)
IL6STInterleukin 6 signal transducer. (928 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
FGFR2Fibroblast growth factor receptor. (823 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
PAX6Paired box 6. (436 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
Map2k2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (498 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
LOC101955676RING-type domain-containing protein. (326 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
SMARCAD1Uncharacterized protein. (1027 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
INHBCInhibin subunit beta C. (352 aa)
ZIC1Zic family member 1. (447 aa)
MAPK3Mitogen-activated protein kinase. (361 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
FGFR4Fibroblast growth factor receptor. (801 aa)
HESX1HESX homeobox 1. (184 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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