STRINGSTRING
RAC1 RAC1 PTK6 PTK6 MS4A2 MS4A2 SRMS SRMS IL13 IL13 MAP2K1 MAP2K1 Pla2g4b Pla2g4b MAPK3 MAPK3 PLA2G4C PLA2G4C PIK3CB PIK3CB KRAS KRAS MAPK10 MAPK10 Pik3r2 Pik3r2 Map2k2 Map2k2 AKT2 AKT2 GAB2 GAB2 BTK BTK PLCG2 PLCG2 SYK SYK FCER1G FCER1G FYN FYN IL5 IL5 MAP2K3 MAP2K3 LOC101962660 LOC101962660 AKT3 AKT3 VAV1 VAV1 ALOX5AP ALOX5AP INPP5D INPP5D PLCG1 PLCG1 MAPK8 MAPK8 GRB2 GRB2 TNF TNF PIK3CA PIK3CA PDPK1 PDPK1 CSF2 CSF2 RAC3 RAC3 I3MM52_ICTTR I3MM52_ICTTR PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F MAPK1 MAPK1 MAPK12 MAPK12 MAPK11 MAPK11 LCP2 LCP2 LOC101965906 LOC101965906 I3MSG9_ICTTR I3MSG9_ICTTR NRAS NRAS ALOX5 ALOX5 RAC2 RAC2 MAP2K4 MAP2K4 ERAS ERAS VAV2 VAV2 JMJD7 JMJD7 MAPK14 MAPK14 MAPK13 MAPK13 LOC101968118 LOC101968118 LAT LAT PIK3R1 PIK3R1 ENSSTOP00000027636 ENSSTOP00000027636 LOC101975023 LOC101975023 ENSSTOP00000028111 ENSSTOP00000028111 AKT1 AKT1 HRAS HRAS Pik3r3 Pik3r3 LYN LYN Pik3cd Pik3cd SOS1 SOS1 MAP2K7 MAP2K7 MAPK9 MAPK9 Csde1 Csde1 PLA2G4A PLA2G4A VAV3 VAV3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAC1Rac family small GTPase 1. (211 aa)
PTK6Tyrosine-protein kinase. (450 aa)
MS4A2Membrane spanning 4-domains A2. (235 aa)
SRMSTyrosine-protein kinase. (534 aa)
IL13Interleukin 13. (130 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
Pla2g4bPhospholipase A2. (774 aa)
MAPK3Mitogen-activated protein kinase. (361 aa)
PLA2G4CPhospholipase A2 group IVC. (571 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MAPK10Mitogen-activated protein kinase. (492 aa)
Pik3r2Uncharacterized protein. (724 aa)
Map2k2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (498 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
GAB2GRB2 associated binding protein 2. (638 aa)
BTKTyrosine-protein kinase. (659 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
SYKTyrosine-protein kinase. (626 aa)
FCER1GFc fragment of IgE receptor Ig. (86 aa)
FYNTyrosine-protein kinase. (537 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
LOC101962660Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (824 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
VAV1Vav guanine nucleotide exchange factor 1. (822 aa)
ALOX5APArachidonate 5-lipoxygenase activating protein. (161 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1213 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (556 aa)
CSF2Colony stimulating factor 2. (138 aa)
RAC3Rac family small GTPase 3. (185 aa)
I3MM52_ICTTRIg-like domain-containing protein. (222 aa)
PLA2G4EPhospholipase A2. (876 aa)
PLA2G4DPhospholipase A2. (827 aa)
PLA2G4FPhospholipase A2. (840 aa)
MAPK1Mitogen-activated protein kinase. (331 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
MAPK11Mitogen-activated protein kinase. (325 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
LOC101965906Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (970 aa)
I3MSG9_ICTTRIg-like domain-containing protein. (186 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
ALOX5Arachidonate 5-lipoxygenase. (663 aa)
RAC2Rac family small GTPase 2. (192 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (360 aa)
ERASES cell expressed Ras. (227 aa)
VAV2Vav guanine nucleotide exchange factor 2. (745 aa)
JMJD7Jumonji domain containing 7. (316 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (326 aa)
LOC101968118Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (932 aa)
LATLinker for activation of T cells. (234 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSSTOP00000027636Ig-like domain-containing protein. (165 aa)
LOC101975023CSD_1 domain-containing protein. (729 aa)
ENSSTOP00000028111Ig-like domain-containing protein. (135 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
Pik3r3Uncharacterized protein. (461 aa)
LYNTyrosine-protein kinase. (512 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1334 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (469 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
Csde1Uncharacterized protein. (555 aa)
PLA2G4APhospholipase A2. (750 aa)
VAV3Vav guanine nucleotide exchange factor 3. (847 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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