(35 nodes) Phototransduction network (Ictidomys tridecemlineatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GUCY2D	Guanylate cyclase. (1108 aa)
	CNGA1	Cyclic nucleotide gated channel subunit alpha 1. (683 aa)
	ENSSTOP00000029069	EF-hand domain-containing protein. (222 aa)
	GUCA1B	Guanylate cyclase activator 1B. (201 aa)
	CALM3	Calmodulin 3. (149 aa)
	MORC1	MORC family CW-type zinc finger 1. (871 aa)
	ENSSTOP00000032237	Uncharacterized protein; Belongs to the calmodulin family. (148 aa)
	SLC24A1	Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (945 aa)
	I3M9X0_ICTTR	Cyclic nucleotide-binding domain-containing protein. (870 aa)
	CALML3	Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
	GNAT2	G protein subunit alpha transducin 2. (354 aa)
	PDE6A	Phosphodiesterase. (860 aa)
	RGS11	Regulator of G protein signaling 11. (465 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	EFCAB3	EF-hand calcium binding domain 3. (432 aa)
	GNB1	G protein subunit beta 1. (340 aa)
	RCVRN	Recoverin. (202 aa)
	GUCA1C	Guanylate cyclase activator 1C. (231 aa)
	SAG	S-antigen visual arrestin. (401 aa)
	CALML4	Calmodulin like 4. (153 aa)
	GNAT1	G protein subunit alpha transducin 1. (350 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (148 aa)
	GRK1	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (564 aa)
	RHO	Rhodopsin. (348 aa)
	CALML6	Calmodulin like 6. (172 aa)
	Grk7	Rhodopsin kinase GRK7; Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO). (548 aa)
	Guca1a	Uncharacterized protein. (202 aa)
	TMCO3	Transmembrane and coiled-coil domains 3. (678 aa)
	RGS9	Regulator of G protein signaling 9. (675 aa)
	PDE6B	Phosphodiesterase. (855 aa)
	CALM2	Calmodulin 2; Belongs to the calmodulin family. (149 aa)
	SLC24A2	Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (665 aa)
	LOC101969867	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (209 aa)
	PDE6G	Phosphodiesterase 6G. (87 aa)
	ENSSTOP00000029937	Uncharacterized protein; Belongs to the calmodulin family. (67 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALM1	CALML3	ENSSTOP00000014633	ENSSTOP00000007300	Calmodulin 1; Belongs to the calmodulin family.	Calmodulin like 3; Belongs to the calmodulin family.	0.671
CALM1	CALML4	ENSSTOP00000014633	ENSSTOP00000013905	Calmodulin 1; Belongs to the calmodulin family.	Calmodulin like 4.	0.589
CALM1	CALML6	ENSSTOP00000014633	ENSSTOP00000016185	Calmodulin 1; Belongs to the calmodulin family.	Calmodulin like 6.	0.644
CALM1	CNGA1	ENSSTOP00000014633	ENSSTOP00000001145	Calmodulin 1; Belongs to the calmodulin family.	Cyclic nucleotide gated channel subunit alpha 1.	0.633
CALM1	GRK1	ENSSTOP00000014633	ENSSTOP00000015595	Calmodulin 1; Belongs to the calmodulin family.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.526
CALM1	Grk7	ENSSTOP00000014633	ENSSTOP00000020054	Calmodulin 1; Belongs to the calmodulin family.	Rhodopsin kinase GRK7; Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).	0.406
CALM1	I3M9X0_ICTTR	ENSSTOP00000014633	ENSSTOP00000006724	Calmodulin 1; Belongs to the calmodulin family.	Cyclic nucleotide-binding domain-containing protein.	0.775
CALM2	CALML3	ENSSTOP00000023145	ENSSTOP00000007300	Calmodulin 2; Belongs to the calmodulin family.	Calmodulin like 3; Belongs to the calmodulin family.	0.671
CALM2	CALML4	ENSSTOP00000023145	ENSSTOP00000013905	Calmodulin 2; Belongs to the calmodulin family.	Calmodulin like 4.	0.589
CALM2	CALML6	ENSSTOP00000023145	ENSSTOP00000016185	Calmodulin 2; Belongs to the calmodulin family.	Calmodulin like 6.	0.645
CALM2	CNGA1	ENSSTOP00000023145	ENSSTOP00000001145	Calmodulin 2; Belongs to the calmodulin family.	Cyclic nucleotide gated channel subunit alpha 1.	0.633
CALM2	GRK1	ENSSTOP00000023145	ENSSTOP00000015595	Calmodulin 2; Belongs to the calmodulin family.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.526
CALM2	Grk7	ENSSTOP00000023145	ENSSTOP00000020054	Calmodulin 2; Belongs to the calmodulin family.	Rhodopsin kinase GRK7; Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).	0.406
CALM2	I3M9X0_ICTTR	ENSSTOP00000023145	ENSSTOP00000006724	Calmodulin 2; Belongs to the calmodulin family.	Cyclic nucleotide-binding domain-containing protein.	0.775
CALM3	CALML3	ENSSTOP00000027029	ENSSTOP00000007300	Calmodulin 3.	Calmodulin like 3; Belongs to the calmodulin family.	0.671
CALM3	CALML4	ENSSTOP00000027029	ENSSTOP00000013905	Calmodulin 3.	Calmodulin like 4.	0.589
CALM3	CALML6	ENSSTOP00000027029	ENSSTOP00000016185	Calmodulin 3.	Calmodulin like 6.	0.645
CALM3	CNGA1	ENSSTOP00000027029	ENSSTOP00000001145	Calmodulin 3.	Cyclic nucleotide gated channel subunit alpha 1.	0.633
CALM3	GRK1	ENSSTOP00000027029	ENSSTOP00000015595	Calmodulin 3.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.526
CALM3	Grk7	ENSSTOP00000027029	ENSSTOP00000020054	Calmodulin 3.	Rhodopsin kinase GRK7; Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).	0.406