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ENSSTOP00000032237 ENSSTOP00000032237 LOC101966144 LOC101966144 PLA2G4A PLA2G4A Csde1 Csde1 PLCB3 PLCB3 MAPK9 MAPK9 ADCY8 ADCY8 MAP2K7 MAP2K7 PTK2B PTK2B ENSSTOP00000029937 ENSSTOP00000029937 SOS1 SOS1 CACNA1D CACNA1D ENSSTOP00000029069 ENSSTOP00000029069 PRKACB PRKACB ADCY7 ADCY7 HRAS HRAS CACNA1S CACNA1S LOC101975023 LOC101975023 LOC101967288 LOC101967288 PLCB2 PLCB2 ITPR1 ITPR1 CALM3 CALM3 Gnas Gnas CALML3 CALML3 RRAD RRAD MAP3K1 MAP3K1 EGFR EGFR ADCY3 ADCY3 PTRHD1 PTRHD1 ADCY9 ADCY9 ADCY2 ADCY2 PRKCD PRKCD ADCY6 ADCY6 PRKCA PRKCA MAP3K4 MAP3K4 ADCY4 ADCY4 Map2k2 Map2k2 PRKACA PRKACA MAPK10 MAPK10 PLA2G4C PLA2G4C MAPK3 MAPK3 Cdc42 Cdc42 Pla2g4b Pla2g4b FSHB FSHB CAMK2B CAMK2B MAPK7 MAPK7 ADCY5 ADCY5 MAP3K2 MAP3K2 ITPR3 ITPR3 PLCB4 PLCB4 CAMK2G CAMK2G ITPR2 ITPR2 HBEGF HBEGF ATF4 ATF4 MAPK13 MAPK13 CALM2 CALM2 MAPK14 MAPK14 CAMK2D CAMK2D JMJD7 JMJD7 JUN JUN REM1 REM1 GNA11 GNA11 ERAS ERAS MMP14 MMP14 CGA CGA I3N4S4_ICTTR I3N4S4_ICTTR ARSI ARSI MAP2K4 MAP2K4 MMP2 MMP2 EGR1 EGR1 CACNA1F CACNA1F CALML6 CALML6 GNRHR GNRHR GNAQ GNAQ PTX3 PTX3 NRAS NRAS CALM1 CALM1 PLCB1 PLCB1 CALML4 CALML4 MAPK11 MAPK11 MAPK12 MAPK12 PLD2 PLD2 CACNA1C CACNA1C MAPK1 MAPK1 PLA2G4F PLA2G4F PLA2G4D PLA2G4D PLA2G4E PLA2G4E LOC101978140 LOC101978140 I3MLY1_ICTTR I3MLY1_ICTTR GRB2 GRB2 MAPK8 MAPK8 PRKCB PRKCB GEM GEM ELK3 ELK3 EFCAB3 EFCAB3 PLD1 PLD1 ELK1 ELK1 MAP2K3 MAP2K3 KRAS KRAS MAP2K1 MAP2K1 CAMK2A CAMK2A MAP3K3 MAP3K3 GNRH1 GNRH1 ADCY1 ADCY1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSSTOP00000032237Uncharacterized protein; Belongs to the calmodulin family. (148 aa)
LOC101966144Uncharacterized protein. (147 aa)
PLA2G4APhospholipase A2. (750 aa)
Csde1Uncharacterized protein. (555 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1255 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (469 aa)
PTK2BProtein tyrosine kinase 2 beta. (968 aa)
ENSSTOP00000029937Uncharacterized protein; Belongs to the calmodulin family. (67 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1334 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2179 aa)
ENSSTOP00000029069EF-hand domain-containing protein. (222 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1795 aa)
LOC101975023CSD_1 domain-containing protein. (729 aa)
LOC101967288Uncharacterized protein. (848 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2748 aa)
CALM3Calmodulin 3. (149 aa)
GnasUncharacterized protein. (244 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1437 aa)
EGFRReceptor protein-tyrosine kinase. (1192 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (955 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1553 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
Map2k2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (498 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (334 aa)
MAPK10Mitogen-activated protein kinase. (492 aa)
PLA2G4CPhospholipase A2 group IVC. (571 aa)
MAPK3Mitogen-activated protein kinase. (361 aa)
Cdc42Uncharacterized protein. (191 aa)
Pla2g4bPhospholipase A2. (774 aa)
FSHBFollicle stimulating hormone subunit beta. (130 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (812 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (619 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (512 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
ATF4Activating transcription factor 4. (352 aa)
MAPK13Mitogen-activated protein kinase. (326 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (514 aa)
JMJD7Jumonji domain containing 7. (316 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (309 aa)
GNA11G protein subunit alpha 11. (359 aa)
ERASES cell expressed Ras. (227 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
I3N4S4_ICTTRUncharacterized protein. (162 aa)
ARSIArylsulfatase family member I. (572 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (360 aa)
MMP2Matrix metallopeptidase 2. (662 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1981 aa)
CALML6Calmodulin like 6. (172 aa)
GNRHRGonadotropin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (328 aa)
GNAQG protein subunit alpha q. (313 aa)
PTX3Pentraxin 3. (367 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (148 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
CALML4Calmodulin like 4. (153 aa)
MAPK11Mitogen-activated protein kinase. (325 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
PLD2Phospholipase. (933 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2193 aa)
MAPK1Mitogen-activated protein kinase. (331 aa)
PLA2G4FPhospholipase A2. (840 aa)
PLA2G4DPhospholipase A2. (827 aa)
PLA2G4EPhospholipase A2. (876 aa)
LOC101978140Luteinizing hormone beta subunit. (141 aa)
I3MLY1_ICTTRG_PROTEIN_RECEP_F1_2 domain-containing protein. (87 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
ELK3ETS transcription factor ELK3. (407 aa)
EFCAB3EF-hand calcium binding domain 3. (432 aa)
PLD1Phospholipase. (1037 aa)
ELK1ETS transcription factor ELK1. (428 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (657 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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