103 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
	LOC101963097	Uncharacterized protein. (243 aa)
	CDC26	Cell division cycle 26. (85 aa)
	MAPK3	Mitogen-activated protein kinase. (361 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
	Ccnb2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa)
	KIF22	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (664 aa)
	MAPK10	Mitogen-activated protein kinase. (492 aa)
	Pik3r2	Uncharacterized protein. (724 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (334 aa)
	Cpeb2	RRM domain-containing protein. (262 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (754 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
	I3M249_ICTTR	Uncharacterized protein. (683 aa)
	CCNA1	Cyclin A1; Belongs to the cyclin family. (421 aa)
	ARAF	A-Raf proto-oncogene, serine/threonine kinase. (606 aa)
	ANAPC1	Anaphase promoting complex subunit 1. (1891 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	I3M4Y3_ICTTR	Protein kinase domain-containing protein. (142 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (955 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (733 aa)
	AURKB	Aurora kinase B; Belongs to the protein kinase superfamily. (345 aa)
	PTRHD1	Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
	CDK3	Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (304 aa)
	CDC23	Cell division cycle 23. (599 aa)
	ANAPC10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
	CDC27	Cell division cycle 27. (848 aa)
	RRAD	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
	CCNA2	Cyclin A2; Belongs to the cyclin family. (420 aa)
	CDC25C	Cell division cycle 25C. (427 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
	HSP90AA1	Heat shock protein 90 alpha family class A member 1. (733 aa)
	LOC101962660	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (824 aa)
	ANAPC5	Anaphase promoting complex subunit 5. (691 aa)
	MAD2L2	Mitotic arrest deficient 2 like 2. (211 aa)
	RPS6KA3	Ribosomal protein S6 kinase. (740 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	GEM	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1368 aa)
	Aurka	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (363 aa)
	ANAPC7	Anaphase promoting complex subunit 7. (581 aa)
	GNAI1	G protein subunit alpha i1. (354 aa)
	PLK1	Serine/threonine-protein kinase PLK. (601 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	MAPK1	Mitogen-activated protein kinase. (331 aa)
	CDC25A	Cell division cycle 25A. (513 aa)
	MAPK12	Mitogen-activated protein kinase. (325 aa)
	MAPK11	Mitogen-activated protein kinase. (325 aa)
	PDE3B	Phosphodiesterase. (1046 aa)
	ANAPC4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa)
	GNAI2	G protein subunit alpha i2. (355 aa)
	LOC101965906	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (970 aa)
	Anapc11	RING-type domain-containing protein. (84 aa)
	MOS	MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (349 aa)
	Ins	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	Cpeb1	Uncharacterized protein. (566 aa)
	PGR	Progesterone receptor. (932 aa)
	SPDYA	Speedy/RINGO cell cycle regulator family member A. (312 aa)
	I3N4N6_ICTTR	Rhodanese domain-containing protein. (465 aa)
	RAF1	Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
	STK10	Serine/threonine kinase 10. (968 aa)
	CPEB3	Cytoplasmic polyadenylation element binding protein 3. (697 aa)
	Anapc13	Uncharacterized protein. (74 aa)
	LOC101961406	Uncharacterized protein. (172 aa)
	AP5S1	Adaptor related protein complex 5 subunit sigma 1. (200 aa)
	REM1	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (309 aa)
	HSP90AB1	Heat shock protein 90 alpha family class B member 1. (724 aa)
	MAD2L1	Mitotic arrest deficient 2 like 1. (205 aa)
	Cdc25b	Rhodanese domain-containing protein. (572 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	LOC101975245	HATPase_c domain-containing protein. (733 aa)
	MAPK13	Mitogen-activated protein kinase. (326 aa)
	PKMYT1	Protein kinase, membrane associated tyrosine/threonine 1; Belongs to the protein kinase superfamily. (489 aa)
	LOC101968118	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (932 aa)
	LOC101974796	Uncharacterized protein; Belongs to the cyclin family. (387 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	ENSSTOP00000026345	Protein kinase domain-containing protein. (386 aa)
	ENSSTOP00000026851	Uncharacterized protein. (61 aa)
	CPEB4	Cytoplasmic polyadenylation element binding protein 4. (729 aa)
	TMEM82	Transmembrane protein 82. (380 aa)
	CDC16	Cell division cycle 16. (614 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
	FZR1	Fizzy and cell division cycle 20 related 1. (493 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	ENSSTOP00000028494	RRM domain-containing protein. (160 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
	CDK2	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	CCNB1	Cyclin B1; Belongs to the cyclin family. (429 aa)
	Pik3r3	Uncharacterized protein. (461 aa)
	Pik3cd	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
	IGF1	Insulin like growth factor 1. (166 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	RPS6KA6	Ribosomal protein S6 kinase. (830 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (744 aa)
	ANAPC2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (830 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSSTOP00000007821	ENSSTOP00000004376	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.599
ADCY1	ADCY3	ENSSTOP00000007821	ENSSTOP00000005426	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.843
ADCY1	ADCY4	ENSSTOP00000007821	ENSSTOP00000002179	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.587
ADCY1	ADCY5	ENSSTOP00000007821	ENSSTOP00000000037	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.580
ADCY1	ADCY6	ENSSTOP00000007821	ENSSTOP00000003745	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.580
ADCY1	ADCY7	ENSSTOP00000007821	ENSSTOP00000028572	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.619
ADCY1	ADCY8	ENSSTOP00000007821	ENSSTOP00000030610	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.843
ADCY1	ADCY9	ENSSTOP00000007821	ENSSTOP00000004525	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.833
ADCY1	AKT1	ENSSTOP00000007821	ENSSTOP00000028457	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.859
ADCY1	AKT2	ENSSTOP00000007821	ENSSTOP00000002612	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.859
ADCY1	AKT3	ENSSTOP00000007821	ENSSTOP00000009513	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.859
ADCY1	GNAI1	ENSSTOP00000007821	ENSSTOP00000010973	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i1.	0.890
ADCY1	GNAI2	ENSSTOP00000007821	ENSSTOP00000014501	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i2.	0.891
ADCY1	GNAI3	ENSSTOP00000007821	ENSSTOP00000007797	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i3.	0.887
ADCY1	PDE3B	ENSSTOP00000007821	ENSSTOP00000014424	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.898
ADCY1	PRKACA	ENSSTOP00000007821	ENSSTOP00000002080	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.889
ADCY1	PRKACB	ENSSTOP00000007821	ENSSTOP00000028928	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.892
ADCY1	PTRHD1	ENSSTOP00000007821	ENSSTOP00000005391	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Peptidyl-tRNA hydrolase domain containing 1.	0.787
ADCY2	ADCY1	ENSSTOP00000004376	ENSSTOP00000007821	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.599
ADCY2	ADCY3	ENSSTOP00000004376	ENSSTOP00000005426	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.542