STRINGSTRING
NFKB1 NFKB1 TRAF2 TRAF2 MAPK8 MAPK8 CPT1A CPT1A TNF TNF NFKBIE NFKBIE ACSL5 ACSL5 CPT1B CPT1B PRKAG1 PRKAG1 PCK1 PCK1 ADIPOR1 ADIPOR1 ADIPOQ ADIPOQ CHUK CHUK AGRP AGRP TNFRSF1B TNFRSF1B LEP LEP G6PC G6PC RXRA RXRA I3MY97_ICTTR I3MY97_ICTTR RELA RELA LOC101975126 LOC101975126 IRS1 IRS1 ADIPOR2 ADIPOR2 RXRB RXRB NFKBIB NFKBIB PRKCQ PRKCQ LEPR LEPR PTPN11 PTPN11 LOC101957161 LOC101957161 LOC101958832 LOC101958832 ACSL3 ACSL3 IRS4 IRS4 NPY NPY PRKAA1 PRKAA1 CPT1C CPT1C CD36 CD36 PPARGC1A PPARGC1A IKBKG IKBKG PRKAG2 PRKAG2 SLC2A1 SLC2A1 AKT1 AKT1 ACSBG1 ACSBG1 CAMKK2 CAMKK2 Acsl6 Acsl6 MAPK9 MAPK9 PRKAB2 PRKAB2 MTOR MTOR MAPK10 MAPK10 STK11 STK11 AKT2 AKT2 LOC101967364 LOC101967364 ACACB ACACB ACSL4 ACSL4 IKBKB IKBKB POMC POMC PRKAG3 PRKAG3 JAK2 JAK2 STAT3 STAT3 NOSTRIN NOSTRIN G6PC3 G6PC3 G6PC2 G6PC2 I3M9W2_ICTTR I3M9W2_ICTTR PCK2 PCK2 NFKBIA NFKBIA SLC2A4 SLC2A4 PRKAB1 PRKAB1 ACSL1 ACSL1 TNFRSF1A TNFRSF1A RXRG RXRG PRKAA2 PRKAA2 AKT3 AKT3 SOCS3 SOCS3 PPARA PPARA TRADD TRADD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NFKB1Nuclear factor kappa B subunit 1. (985 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
NFKBIENFKB inhibitor epsilon. (362 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (683 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
ADIPOR1Uncharacterized protein. (375 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (769 aa)
AGRPAgouti related neuropeptide. (132 aa)
TNFRSF1BTNF receptor superfamily member 1B. (436 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
RXRARetinoid X receptor alpha. (461 aa)
I3MY97_ICTTRUncharacterized protein. (155 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
LOC101975126Uncharacterized protein. (498 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
ADIPOR2Adiponectin receptor 2. (386 aa)
RXRBRetinoid X receptor beta. (531 aa)
NFKBIBNFKB inhibitor beta. (359 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
LEPRLeptin receptor. (1148 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
LOC101957161AMP-binding domain-containing protein. (657 aa)
LOC101958832MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (490 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
IRS4Insulin receptor substrate 4. (1228 aa)
NPYNeuropeptide Y. (97 aa)
PRKAA1Non-specific serine/threonine protein kinase. (561 aa)
CPT1CCarnitine palmitoyltransferase 1C. (834 aa)
CD36CD36 molecule; Belongs to the CD36 family. (473 aa)
PPARGC1APPARG coactivator 1 alpha. (803 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (492 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (542 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (730 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (587 aa)
Acsl6AMP-binding domain-containing protein. (722 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2577 aa)
MAPK10Mitogen-activated protein kinase. (492 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (437 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
LOC101967364Uncharacterized protein. (70 aa)
ACACBAcetyl-CoA carboxylase beta. (2328 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
POMCProopiomelanocortin. (212 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (490 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
STAT3Signal transducer and activator of transcription. (748 aa)
NOSTRINNitric oxide synthase trafficking. (505 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
I3M9W2_ICTTRAMP-binding domain-containing protein. (358 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
TNFRSF1ATNF receptor superfamily member 1A. (437 aa)
RXRGRetinoid X receptor gamma. (463 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
SOCS3Suppressor of cytokine signaling 3. (227 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
TRADDTNFRSF1A associated via death domain. (302 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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