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Casp3 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) | ||||
COL4A4 | Collagen type IV alpha 4 chain. (1583 aa) | ||||
CCND1 | Cyclin D1. (250 aa) | ||||
EDN1 | Endothelin 1. (202 aa) | ||||
SERPINE1 | Serpin family E member 1; Belongs to the serpin family. (402 aa) | ||||
NOX3 | NADPH oxidase 3. (567 aa) | ||||
Cdc42 | Uncharacterized protein. (191 aa) | ||||
MAPK3 | Mitogen-activated protein kinase. (361 aa) | ||||
Cdk4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) | ||||
PLCD1 | Phosphoinositide phospholipase C. (756 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (492 aa) | ||||
Pik3r2 | Uncharacterized protein. (724 aa) | ||||
IL1A | Interleukin-1; Belongs to the IL-1 family. (268 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (200 aa) | ||||
VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (417 aa) | ||||
FN1 | Fibronectin 1. (2474 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa) | ||||
PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa) | ||||
CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) | ||||
SMAD2 | Mothers against decapentaplegic homolog. (467 aa) | ||||
COL4A6 | Collagen type IV alpha 6 chain. (1686 aa) | ||||
COL4A1 | Collagen type IV alpha 1 chain. (1671 aa) | ||||
F3 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (293 aa) | ||||
PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) | ||||
I3M4W8_ICTTR | Uncharacterized protein. (207 aa) | ||||
NOX1 | NADPH oxidase 1. (561 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa) | ||||
VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (359 aa) | ||||
JAK2 | Tyrosine-protein kinase. (1132 aa) | ||||
STAT5B | Signal transducer and activator of transcription. (765 aa) | ||||
STAT5A | Signal transducer and activator of transcription. (773 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (748 aa) | ||||
RAC1 | Rac family small GTPase 1. (211 aa) | ||||
NFATC1 | Nuclear factor of activated T cells 1. (941 aa) | ||||
NOX4 | NADPH oxidase 4. (578 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (750 aa) | ||||
VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (392 aa) | ||||
SELE | Selectin E. (495 aa) | ||||
PLCD3 | Phosphoinositide phospholipase C. (782 aa) | ||||
KRAS | KRAS proto-oncogene, GTPase. (189 aa) | ||||
Foxo1 | Forkhead box protein O1; Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalc [...] (535 aa) | ||||
LOC101962660 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (824 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
SMAD3 | Mothers against decapentaplegic homolog. (425 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
COL1A2 | Collagen type I alpha 2 chain. (1366 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (985 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa) | ||||
PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (489 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (192 aa) | ||||
VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (184 aa) | ||||
MAPK1 | Mitogen-activated protein kinase. (331 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (325 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (325 aa) | ||||
PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) | ||||
LOC101965906 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (970 aa) | ||||
CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
PLCE1 | Phosphoinositide phospholipase C. (2298 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (195 aa) | ||||
I3MVL6_ICTTR | Uncharacterized protein. (192 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) | ||||
MMP2 | Matrix metallopeptidase 2. (662 aa) | ||||
SMAD4 | Mothers against decapentaplegic homolog. (552 aa) | ||||
AGT | Angiotensinogen; Belongs to the serpin family. (477 aa) | ||||
AGTR1 | Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (360 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) | ||||
I3N090_ICTTR | Uncharacterized protein. (207 aa) | ||||
LOC101960206 | Uncharacterized protein. (207 aa) | ||||
Vcam1 | Vascular cell adhesion molecule 1. (657 aa) | ||||
XK | XK-related protein. (443 aa) | ||||
I3N4S4_ICTTR | Uncharacterized protein. (162 aa) | ||||
COL4A2 | Collagen type IV alpha 2 chain. (1712 aa) | ||||
PIM1 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa) | ||||
ERAS | ES cell expressed Ras. (227 aa) | ||||
JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) | ||||
LOC101969207 | C-C motif chemokine. (136 aa) | ||||
TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) | ||||
CYBB | Cytochrome b-245 beta chain. (549 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (326 aa) | ||||
ENSSTOP00000024190 | Protein kinase domain-containing protein. (266 aa) | ||||
PLCD4 | Phosphoinositide phospholipase C. (783 aa) | ||||
PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa) | ||||
LOC101968118 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (932 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) | ||||
AGER | Advanced glycosylation end-product specific receptor. (450 aa) | ||||
COL1A1 | Collagen type I alpha 1 chain. (1268 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
ICAM1 | Intercellular adhesion molecule 1. (531 aa) | ||||
PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa) | ||||
LOC101975023 | CSD_1 domain-containing protein. (729 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
MFF | Mitochondrial fission factor. (316 aa) | ||||
Pik3r3 | Uncharacterized protein. (461 aa) | ||||
Pik3cd | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (424 aa) | ||||
PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1255 aa) | ||||
NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1228 aa) | ||||
Csde1 | Uncharacterized protein. (555 aa) | ||||
COL3A1 | Collagen type III alpha 1 chain. (1462 aa) | ||||
ENSSTOP00000031310 | Uncharacterized protein; Belongs to the peptidase C14A family. (233 aa) | ||||
LOC101966144 | Uncharacterized protein. (147 aa) |