STRINGSTRING
RAP1B RAP1B SLC26A3 SLC26A3 ADCY3 ADCY3 PTRHD1 PTRHD1 I3M6L1_ICTTR I3M6L1_ICTTR CD38 CD38 ADCY9 ADCY9 ADCY2 ADCY2 Rhoa Rhoa PLA2G1B PLA2G1B ADCY6 ADCY6 LOC101964433 LOC101964433 Atp1a3 Atp1a3 RAB27B RAB27B SLC12A2 SLC12A2 PRKCA PRKCA ADCY4 ADCY4 PNLIP PNLIP ADCY5 ADCY5 CLCA2 CLCA2 CTRL CTRL PLA2G3 PLA2G3 CPB2 CPB2 ATP2B4 ATP2B4 OVCH2 OVCH2 SLC9A1 SLC9A1 CPA1 CPA1 CPA4 CPA4 PLA2G2D PLA2G2D CELA1 CELA1 CPA2 CPA2 PNLIPRP2 PNLIPRP2 PNLIPRP1 PNLIPRP1 ADCY1 ADCY1 CPA3 CPA3 CPB1 CPB1 LOC101960778 LOC101960778 PLA2G12B PLA2G12B PLA2G10 PLA2G10 ATP1A4 ATP1A4 PLA2G12A PLA2G12A RAC1 RAC1 ATP1B4 ATP1B4 SCTR SCTR ATP2B2 ATP2B2 Ctrc Ctrc ADCY8 ADCY8 ATP2B3 ATP2B3 PLCB3 PLCB3 ENSSTOP00000031001 ENSSTOP00000031001 LOC101954605 LOC101954605 ATP1A1 ATP1A1 ATP2B1 ATP2B1 RAB27A RAB27A TRPC1 TRPC1 ATP2A1 ATP2A1 ADCY7 ADCY7 SLC4A4 SLC4A4 LOC101967288 LOC101967288 PLCB2 PLCB2 ITPR1 ITPR1 PLA2G5 PLA2G5 Gnas Gnas SCT SCT PRKCG PRKCG ITPR3 ITPR3 LOC101966592 LOC101966592 ENSSTOP00000025329 ENSSTOP00000025329 ATP1A2 ATP1A2 KCNMA1 KCNMA1 ATP2A2 ATP2A2 PLCB4 PLCB4 ITPR2 ITPR2 PLA2G2F PLA2G2F RAB3D RAB3D LOC101958816 LOC101958816 BST1 BST1 LOC101966003 LOC101966003 Tpcn2 Tpcn2 CLCA4 CLCA4 LOC101966300 LOC101966300 LOC101968603 LOC101968603 CHRM3 CHRM3 RAB8A RAB8A CCK CCK CEL CEL LOC101973966 LOC101973966 KCNQ1 KCNQ1 Rhoc Rhoc PLA2G2A PLA2G2A LOC101959358 LOC101959358 CCKAR CCKAR ATP1B2 ATP1B2 LOC101974615 LOC101974615 CPA6 CPA6 LOC101968389 LOC101968389 LOC101973687 LOC101973687 Fxyd2 Fxyd2 RAP1A RAP1A I3MRE0_ICTTR I3MRE0_ICTTR PLCB1 PLCB1 SLC4A2 SLC4A2 ATP2A3 ATP2A3 RAB11A RAB11A RYR2 RYR2 PRSS37 PRSS37 CA2 CA2 Atp1b3 Atp1b3 PLA2G2E PLA2G2E PRKCB PRKCB ATP1B1 ATP1B1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAP1BRAP1B, member of RAS oncogene family. (159 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (758 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
I3M6L1_ICTTRABC transmembrane type-1 domain-containing protein. (528 aa)
CD38CD38 molecule. (307 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (955 aa)
RhoaRas homolog family member A. (193 aa)
PLA2G1BPhospholipase A(2). (117 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC101964433Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
Atp1a3Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
SLC12A2Solute carrier family 12 member 2. (1108 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
PNLIPPancreatic triacylglycerol lipase; Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones (By similarity). Plays a role in hibernation as a key enzyme that shows high activity at low temperatures. When expressed in the hibernating heart it liberates fatty acids from triglycerides at temperatures as low as 0 degrees Celsius. (465 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
CLCA2Chloride channel accessory 2. (941 aa)
CTRLChymotrypsin like; Belongs to the peptidase S1 family. (264 aa)
PLA2G3Phospholipase A2 group III. (626 aa)
CPB2Carboxypeptidase B2. (423 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1214 aa)
OVCH2Ovochymase 2 (gene/pseudogene); Belongs to the peptidase S1 family. (621 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (810 aa)
CPA1Carboxypeptidase A1. (419 aa)
CPA4Carboxypeptidase A4. (420 aa)
PLA2G2DPhospholipase A(2). (145 aa)
CELA1Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (266 aa)
CPA2Carboxypeptidase A2. (419 aa)
PNLIPRP2Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (481 aa)
PNLIPRP1Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (473 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
CPA3Carboxypeptidase A3. (417 aa)
CPB1Carboxypeptidase B1. (417 aa)
LOC101960778Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
PLA2G12BPhospholipase A2 group XIIB. (195 aa)
PLA2G10Phospholipase A(2). (148 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (987 aa)
PLA2G12APhospholipase A2 group XIIA. (189 aa)
RAC1Rac family small GTPase 1. (211 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (435 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
CtrcPeptidase S1 domain-containing protein. (152 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1255 aa)
ENSSTOP00000031001Uncharacterized protein. (178 aa)
LOC101954605Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (271 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
RAB27ARAB27A, member RAS oncogene family. (220 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (748 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1001 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
SLC4A4Anion exchange protein. (1094 aa)
LOC101967288Uncharacterized protein. (848 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2748 aa)
PLA2G5Phospholipase A(2). (161 aa)
GnasUncharacterized protein. (244 aa)
SCTSecretin. (128 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
LOC101966592Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
ENSSTOP00000025329CLCA domain-containing protein. (336 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1219 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
PLA2G2FPhospholipase A(2). (209 aa)
RAB3DRAB3D, member RAS oncogene family. (219 aa)
LOC101958816Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (269 aa)
BST1Bone marrow stromal cell antigen 1. (311 aa)
LOC101966003Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa)
Tpcn2Uncharacterized protein. (740 aa)
CLCA4Chloride channel accessory 4. (923 aa)
LOC101966300Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
LOC101968603Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (180 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
CCKCholecystokinin. (115 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (558 aa)
LOC101973966Alpha-amylase. (511 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (592 aa)
RhocUncharacterized protein. (193 aa)
PLA2G2APhospholipase A(2). (145 aa)
LOC101959358Uncharacterized protein. (193 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (391 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
LOC101974615Alpha-amylase. (511 aa)
CPA6Carboxypeptidase A6. (438 aa)
LOC101968389Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (320 aa)
LOC101973687Alpha-amylase. (511 aa)
Fxyd2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
I3MRE0_ICTTRVWFA domain-containing protein. (475 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
SLC4A2Anion exchange protein. (1236 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1038 aa)
RAB11AUncharacterized protein. (216 aa)
RYR2Ryanodine receptor 2. (4888 aa)
PRSS37Serine protease 37. (233 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
Atp1b3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (265 aa)
PLA2G2EPhospholipase A(2). (142 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.