51 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABCG8	ATP binding cassette subfamily G member 8. (673 aa)
	SORT1	Sortilin. (765 aa)
	SOAT1	O-acyltransferase. (544 aa)
	MYLIP	Myosin regulatory light chain interacting protein. (437 aa)
	LRP1	LDL receptor related protein 1. (4508 aa)
	LIPG	Lipase G, endothelial type. (500 aa)
	LCAT	Lecithin-cholesterol acyltransferase. (440 aa)
	OSBPL5	Oxysterol-binding protein; Belongs to the OSBP family. (793 aa)
	APOA4	Apolipoprotein A4. (370 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (430 aa)
	APOB	Apolipoprotein B. (4482 aa)
	APOA2	Apolipoprotein A2. (101 aa)
	LDLRAP1	Low density lipoprotein receptor adaptor protein 1. (308 aa)
	LIPA	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (397 aa)
	APOC3	Apolipoprotein C3. (130 aa)
	ANGPTL8	Angiopoietin like 8. (198 aa)
	APOH	Apolipoprotein H. (306 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (473 aa)
	OSBPL8	Oxysterol-binding protein; Belongs to the OSBP family. (890 aa)
	LRP1B	LDL receptor related protein 1B. (4442 aa)
	LRP2	LDL receptor related protein 2. (4656 aa)
	VDAC2	Voltage dependent anion channel 2. (294 aa)
	LIPC	Lipase C, hepatic type. (463 aa)
	ENSSTOP00000030319	Uncharacterized protein. (2101 aa)
	VAPB	VAMP associated protein B and C. (243 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2261 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (473 aa)
	LRPAP1	LDL receptor related protein associated protein 1. (362 aa)
	APOA1	Apolipoprotein A1. (264 aa)
	TSPO	Translocator protein. (169 aa)
	CETP	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (495 aa)
	NR1I3	Nuclear receptor subfamily 1 group I member 3. (357 aa)
	BSND	Barttin CLCNK type accessory beta subunit. (318 aa)
	ANGPTL3	Angiopoietin like 3. (455 aa)
	Pltp	BPI1 domain-containing protein. (147 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (682 aa)
	VDAC3	Voltage dependent anion channel 3. (284 aa)
	NCEH1	Neutral cholesterol ester hydrolase 1. (350 aa)
	CYP7A1	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
	CYP27A1	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (534 aa)
	NPC1	NPC intracellular cholesterol transporter 1. (1277 aa)
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (282 aa)
	ABCB11	ATP binding cassette subfamily B member 11. (1321 aa)
	VDAC1	Voltage dependent anion channel 1. (292 aa)
	NPC2	NPC intracellular cholesterol transporter 2. (149 aa)
	LDLR	Low density lipoprotein receptor. (863 aa)
	ANGPTL4	Angiopoietin like 4. (421 aa)
	STARD3	StAR related lipid transfer domain containing 3. (446 aa)
	VAPA	VAMP associated protein A. (222 aa)
	SOAT2	O-acyltransferase. (524 aa)
	ABCG5	ATP binding cassette subfamily G member 5. (652 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	APOA1	ENSSTOP00000001138	ENSSTOP00000002077	ATP binding cassette subfamily A member 1.	Apolipoprotein A1.	0.963
ABCA1	APOA2	ENSSTOP00000001138	ENSSTOP00000020847	ATP binding cassette subfamily A member 1.	Apolipoprotein A2.	0.529
ABCA1	APOA4	ENSSTOP00000001138	ENSSTOP00000018309	ATP binding cassette subfamily A member 1.	Apolipoprotein A4.	0.731
ABCA1	APOB	ENSSTOP00000001138	ENSSTOP00000020666	ATP binding cassette subfamily A member 1.	Apolipoprotein B.	0.483
ABCA1	CD36	ENSSTOP00000001138	ENSSTOP00000025792	ATP binding cassette subfamily A member 1.	CD36 molecule; Belongs to the CD36 family.	0.562
ABCA1	CETP	ENSSTOP00000001138	ENSSTOP00000003181	ATP binding cassette subfamily A member 1.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.562
ABCA1	CYP7A1	ENSSTOP00000001138	ENSSTOP00000005893	ATP binding cassette subfamily A member 1.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.499
ABCA1	LCAT	ENSSTOP00000001138	ENSSTOP00000015769	ATP binding cassette subfamily A member 1.	Lecithin-cholesterol acyltransferase.	0.563
ABCA1	LIPC	ENSSTOP00000001138	ENSSTOP00000030828	ATP binding cassette subfamily A member 1.	Lipase C, hepatic type.	0.404
ABCA1	MYLIP	ENSSTOP00000001138	ENSSTOP00000011486	ATP binding cassette subfamily A member 1.	Myosin regulatory light chain interacting protein.	0.464
ABCA1	NPC1	ENSSTOP00000001138	ENSSTOP00000005919	ATP binding cassette subfamily A member 1.	NPC intracellular cholesterol transporter 1.	0.461
ABCA1	PCSK9	ENSSTOP00000001138	ENSSTOP00000004831	ATP binding cassette subfamily A member 1.	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.	0.408
ABCA1	Pltp	ENSSTOP00000001138	ENSSTOP00000004557	ATP binding cassette subfamily A member 1.	BPI1 domain-containing protein.	0.444
ABCA1	SCARB1	ENSSTOP00000001138	ENSSTOP00000018988	ATP binding cassette subfamily A member 1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.579
ABCB11	ABCG5	ENSSTOP00000006693	ENSSTOP00000010018	ATP binding cassette subfamily B member 11.	ATP binding cassette subfamily G member 5.	0.439
ABCB11	ABCG8	ENSSTOP00000006693	ENSSTOP00000010027	ATP binding cassette subfamily B member 11.	ATP binding cassette subfamily G member 8.	0.439
ABCB11	APOB	ENSSTOP00000006693	ENSSTOP00000020666	ATP binding cassette subfamily B member 11.	Apolipoprotein B.	0.482
ABCB11	CYP27A1	ENSSTOP00000006693	ENSSTOP00000005904	ATP binding cassette subfamily B member 11.	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	0.416
ABCB11	CYP7A1	ENSSTOP00000006693	ENSSTOP00000005893	ATP binding cassette subfamily B member 11.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.620
ABCB11	LCAT	ENSSTOP00000006693	ENSSTOP00000015769	ATP binding cassette subfamily B member 11.	Lecithin-cholesterol acyltransferase.	0.601