STRINGSTRING
SPTBN2 SPTBN2 ATG101 ATG101 PSMD4 PSMD4 GRIN2B GRIN2B PIK3R4 PIK3R4 PIK3CB PIK3CB WIPI2 WIPI2 PSMB2 PSMB2 MAPK10 MAPK10 Pik3r2 Pik3r2 OMA1 OMA1 GRIN3A GRIN3A ADRM1 ADRM1 AKT2 AKT2 PPIF PPIF RB1CC1 RB1CC1 PRKCA PRKCA WIPI1 WIPI1 Xbp1 Xbp1 KCNC2 KCNC2 AFG3L2 AFG3L2 PSMC2 PSMC2 VDAC3 VDAC3 SP1 SP1 DAB1 DAB1 PSMA1 PSMA1 PUM2 PUM2 TBPL1 TBPL1 VLDLR VLDLR PSMB5 PSMB5 VDAC1 VDAC1 TBP TBP GRIA1 GRIA1 LOC106144614 LOC106144614 C7orf31 C7orf31 Psmc5 Psmc5 TWNK TWNK MAP3K5 MAP3K5 ERN1 ERN1 GRIA3 GRIA3 RBPJL RBPJL PSMD1 PSMD1 GRIN2C GRIN2C KCNC4 KCNC4 LOC101962660 LOC101962660 ATG2A ATG2A FGF12 FGF12 PSMB1 PSMB1 AKT3 AKT3 PSMC3 PSMC3 ULK1 ULK1 Nrbf2 Nrbf2 OSBPL2 OSBPL2 Psmd9 Psmd9 Sem1 Sem1 Slc25a6 Slc25a6 Psma6 Psma6 ATXN2L ATXN2L RELN RELN OPA1 OPA1 PSMB4 PSMB4 TRAF2 TRAF2 RORA RORA PRKCB PRKCB PSMA7 PSMA7 PSMC4 PSMC4 NOP56 NOP56 PSMD6 PSMD6 MAPK8 MAPK8 PIK3CA PIK3CA PSMD7 PSMD7 PSMA2 PSMA2 PSMA3 PSMA3 PIK3C3 PIK3C3 PSMB7 PSMB7 PSMD8 PSMD8 Psmc6 Psmc6 TRPC3 TRPC3 Psmb6 Psmb6 PSMD14 PSMD14 TBPL2 TBPL2 ATXN3 ATXN3 PSMA8 PSMA8 ATP2A3 ATP2A3 ATG2B ATG2B PLCB1 PLCB1 LOC101965906 LOC101965906 LOC101973943 LOC101973943 RYR1 RYR1 I3MXS4_ICTTR I3MXS4_ICTTR I3MXX5_ICTTR I3MXX5_ICTTR I3N1R8_ICTTR I3N1R8_ICTTR KCND3 KCND3 BEAN1 BEAN1 SLC25A4 SLC25A4 ATXN1 ATXN1 AMBRA1 AMBRA1 SLC1A6 SLC1A6 LOC101977589 LOC101977589 GRIN2D GRIN2D BECN2 BECN2 I3NC87_ICTTR I3NC87_ICTTR KCNC1 KCNC1 ATG14 ATG14 MYOD1 MYOD1 PSMD3 PSMD3 GRIN2A GRIN2A KCNC3 KCNC3 ATXN1L ATXN1L Slc25a5 Slc25a5 PUM1 PUM1 ITPR2 ITPR2 PSMB3 PSMB3 ENSSTOP00000024305 ENSSTOP00000024305 PLCB4 PLCB4 ATXN10 ATXN10 GRIN3B GRIN3B ULK2 ULK2 LOC101968118 LOC101968118 ATP2A2 ATP2A2 MCU MCU PSMD13 PSMD13 LOC101972090 LOC101972090 Becn1 Becn1 PSMD2 PSMD2 ENSSTOP00000025153 ENSSTOP00000025153 FGF14 FGF14 ATG13 ATG13 ITPR3 ITPR3 GRIN1 GRIN1 ENSSTOP00000025685 ENSSTOP00000025685 PRKCG PRKCG ENSSTOP00000025775 ENSSTOP00000025775 GRIA2 GRIA2 RBPJ RBPJ PIK3R1 PIK3R1 ENSSTOP00000026081 ENSSTOP00000026081 PSMA5 PSMA5 PSMD11 PSMD11 ITPR1 ITPR1 ENSSTOP00000027174 ENSSTOP00000027174 PLCB2 PLCB2 CIC CIC ENSSTOP00000027865 ENSSTOP00000027865 PDYN PDYN CACNA1A CACNA1A GTF2B GTF2B AKT1 AKT1 ATP2A1 ATP2A1 PSMA4 PSMA4 ENSSTOP00000028908 ENSSTOP00000028908 KAT5 KAT5 Pik3r3 Pik3r3 VDAC2 VDAC2 Pik3cd Pik3cd ENSSTOP00000029537 ENSSTOP00000029537 ENSSTOP00000030001 ENSSTOP00000030001 MAPK9 MAPK9 PLCB3 PLCB3 ENSSTOP00000030705 ENSSTOP00000030705 ATXN2 ATXN2 LOC101978532 LOC101978532 PSMD12 PSMD12 Psmc1 Psmc1 TRPC7 TRPC7 MTOR MTOR Nfya Nfya ENSSTOP00000032525 ENSSTOP00000032525
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2390 aa)
ATG101Autophagy related 101. (218 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1305 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (445 aa)
PSMB2Proteasome subunit beta. (201 aa)
MAPK10Mitogen-activated protein kinase. (492 aa)
Pik3r2Uncharacterized protein. (724 aa)
OMA1OMA1 zinc metallopeptidase. (526 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
ADRM1Adhesion regulating molecule 1. (407 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa)
RB1CC1RB1 inducible coiled-coil 1. (1593 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (422 aa)
Xbp1BZIP domain-containing protein. (351 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (640 aa)
AFG3L2AFG3 like matrix AAA peptidase subunit 2; Belongs to the AAA ATPase family. (683 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
VDAC3Voltage dependent anion channel 3. (284 aa)
SP1Sp1 transcription factor. (788 aa)
DAB1DAB adaptor protein 1. (555 aa)
PSMA1Proteasome subunit alpha type. (266 aa)
PUM2Pumilio RNA binding family member 2. (1064 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
VLDLRVery low density lipoprotein receptor. (873 aa)
PSMB5Proteasome subunit beta. (220 aa)
VDAC1Voltage dependent anion channel 1. (292 aa)
TBPTATA-box binding protein. (323 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (837 aa)
LOC106144614Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
C7orf31Chromosome 7 open reading frame 31. (591 aa)
Psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
TWNKTwinkle mtDNA helicase. (666 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1307 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (972 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (899 aa)
RBPJLRecombination signal binding protein for immunoglobulin kappa J region like. (542 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1047 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (506 aa)
LOC101962660Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (824 aa)
ATG2AAutophagy related 2A. (1911 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
PSMB1Proteasome subunit beta. (240 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1041 aa)
Nrbf2Uncharacterized protein. (287 aa)
OSBPL2Oxysterol-binding protein; Belongs to the OSBP family. (483 aa)
Psmd9PDZ domain-containing protein. (223 aa)
Sem1Uncharacterized protein. (70 aa)
Slc25a6Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa)
Psma6Proteasome subunit alpha type. (148 aa)
ATXN2LAtaxin 2 like. (779 aa)
RELNReelin. (3416 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (947 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
RORARAR related orphan receptor A. (521 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
NOP56NOP56 ribonucleoprotein. (595 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (783 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
Psmc626S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (848 aa)
Psmb6Proteasome subunit beta. (239 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
TBPL2TATA-box binding protein like 2. (352 aa)
ATXN3Ataxin 3 like. (341 aa)
PSMA8Proteasome subunit alpha type. (257 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1038 aa)
ATG2BAutophagy related 2B. (2015 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC101965906Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (970 aa)
LOC101973943BTB domain-containing protein; Belongs to the potassium channel family. (443 aa)
RYR1Ryanodine receptor 1. (4864 aa)
I3MXS4_ICTTRCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
I3MXX5_ICTTRUncharacterized protein. (257 aa)
I3N1R8_ICTTRUncharacterized protein. (199 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
BEAN1Brain expressed associated with NEDD4 1. (259 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
ATXN1Ataxin 1. (792 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1240 aa)
SLC1A6Amino acid transporter. (564 aa)
LOC101977589AAA domain-containing protein. (729 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1394 aa)
BECN2Beclin 2. (412 aa)
I3NC87_ICTTRCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (534 aa)
ATG14Autophagy related 14. (492 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (317 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1423 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (638 aa)
ATXN1LAtaxin 1 like. (689 aa)
Slc25a5Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
PUM1Pumilio RNA binding family member 1. (1188 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSSTOP00000024305Uncharacterized protein. (210 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
ATXN10Ataxin 10. (383 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1031 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1058 aa)
LOC101968118Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (932 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
MCUMitochondrial calcium uniporter. (302 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
LOC101972090AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
Becn1Beclin 1. (448 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
ENSSTOP00000025153PROTEASOME_ALPHA_1 domain-containing protein. (87 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (959 aa)
ENSSTOP00000025685Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (106 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ENSSTOP00000025775Uncharacterized protein. (710 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (522 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSSTOP00000026081Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2748 aa)
ENSSTOP00000027174Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (101 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
CICCapicua transcriptional repressor. (2511 aa)
ENSSTOP00000027865Uncharacterized protein. (255 aa)
PDYNProdynorphin. (245 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2092 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1001 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
ENSSTOP00000028908Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (253 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
Pik3r3Uncharacterized protein. (461 aa)
VDAC2Voltage dependent anion channel 2. (294 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
ENSSTOP00000029537Proteasome subunit beta. (200 aa)
ENSSTOP00000030001AAA domain-containing protein. (334 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1255 aa)
ENSSTOP00000030705Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (267 aa)
ATXN2Ataxin 2. (1230 aa)
LOC101978532Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (100 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
Psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2577 aa)
NfyaUncharacterized protein. (347 aa)
ENSSTOP00000032525Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (94 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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