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| | ENSSTOP00000025685 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (106 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | ENSSTOP00000026081 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC101969049 | Uncharacterized protein. (174 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (467 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (492 aa) |
| | ENSSTOP00000027094 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (208 aa) |
| | ENSSTOP00000027174 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (101 aa) |
| | LOC101975023 | CSD_1 domain-containing protein. (729 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | Tmed7 | GOLD domain-containing protein. (225 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | ENSSTOP00000028887 | Uncharacterized protein. (184 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (468 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (844 aa) |
| | Pik3r3 | Uncharacterized protein. (461 aa) |
| | ATF6B | Activating transcription factor 6 beta. (708 aa) |
| | Ywhaq | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (125 aa) |
| | Pik3cd | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1334 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta. (968 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (469 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | Csde1 | Uncharacterized protein. (555 aa) |
| | ENSSTOP00000031310 | Uncharacterized protein; Belongs to the peptidase C14A family. (233 aa) |
| | LOC101978532 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (100 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | ENSSTOP00000032525 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (94 aa) |
| | STAT3 | Signal transducer and activator of transcription. (748 aa) |
| | DDX58 | DExD/H-box helicase 58. (925 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1437 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (430 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1140 aa) |
| | Faslg | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (69 aa) |
| | JAK3 | Tyrosine-protein kinase. (1042 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (420 aa) |
| | DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (692 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (941 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | BAD | BCL2 associated agonist of cell death. (208 aa) |
| | STAT1 | Signal transducer and activator of transcription. (750 aa) |
| | LOC106144614 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | C7orf31 | Chromosome 7 open reading frame 31. (591 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | E2F2 | E2F transcription factor 2. (432 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | LOC101962660 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (824 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (522 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | TIRAP | TIR domain containing adaptor protein. (222 aa) |
| | ELK1 | ETS transcription factor ELK1. (428 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (520 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (985 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (519 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (489 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | Irak4 | Interleukin 1 receptor associated kinase 4. (457 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa) |
| | CREB3L4 | cAMP responsive element binding protein 3 like 4. (394 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (331 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (490 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (325 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (325 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (509 aa) |
| | STAT2 | Signal transducer and activator of transcription. (805 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (769 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (442 aa) |
| | LOC101965906 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (970 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (692 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1075 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | I3MU87_ICTTR | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (250 aa) |
| | BCL2 | BCL2 apoptosis regulator. (195 aa) |
| | I3MVL6_ICTTR | Uncharacterized protein. (192 aa) |
| | STAT4 | Signal transducer and activator of transcription. (758 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | I3MXS4_ICTTR | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | PPP1R14B | Protein phosphatase 1 regulatory inhibitor subunit 14B. (145 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (840 aa) |
| | I3N090_ICTTR | Uncharacterized protein. (207 aa) |
| | EGR3 | Early growth response 3. (387 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (360 aa) |
| | Ywhaz | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa) |
| | LOC101960206 | Uncharacterized protein. (207 aa) |
| | IRF3 | Interferon regulatory factor 3. (420 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (162 aa) |
| | E2F3 | E2F transcription factor 3. (460 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1247 aa) |
| | JAK1 | Tyrosine-protein kinase. (1142 aa) |
| | LOC101968765 | Uncharacterized protein. (187 aa) |
| | ERAS | ES cell expressed Ras. (227 aa) |
| | TICAM2 | Toll like receptor adaptor molecule 2. (235 aa) |
| | BIRC5 | Baculoviral IAP repeat containing 5. (142 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (480 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) |
| | I3NC87_ICTTR | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | I3NCK5_ICTTR | CARD domain-containing protein. (102 aa) |
| | TLR2 | Toll like receptor 2; Belongs to the Toll-like receptor family. (784 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | Pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (326 aa) |
| | ATF4 | Activating transcription factor 4. (352 aa) |
| | Ikbke | Protein kinase domain-containing protein. (130 aa) |
| | LOC101965246 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | LOC101968118 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (932 aa) |
| | EP300 | E1A binding protein p300. (2423 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (566 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (361 aa) |
| | RB1 | RB transcriptional corepressor 1. (957 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (492 aa) |
| | Pik3r2 | Uncharacterized protein. (724 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa) |
| | Map2k2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (498 aa) |
| | HSPG2 | Heparan sulfate proteoglycan 2. (4368 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (754 aa) |
| | E2F1 | E2F transcription factor 1. (392 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (890 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | TYK2 | Tyrosine-protein kinase. (1194 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (421 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) |
| | Casp3 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) |
| | SLC10A1 | Solute carrier family 10 member 1. (348 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (606 aa) |
| | EGR2 | Early growth response 2. (423 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | I3M4W8_ICTTR | Uncharacterized protein. (207 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa) |
| | IFIH1 | Interferon induced with helicase C domain 1. (974 aa) |
| | CREBBP | CREB binding protein. (2410 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (374 aa) |
| | IRF7 | Interferon regulatory factor 7. (472 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | MMP9 | Matrix metallopeptidase 9. (667 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | STAT5B | Signal transducer and activator of transcription. (765 aa) |
| | STAT5A | Signal transducer and activator of transcription. (773 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (715 aa) |
