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| | FZD1 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (643 aa) |
| | CCDC170 | Coiled-coil domain containing 170. (629 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (696 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (400 aa) |
| | AXIN1 | Axin 1. (869 aa) |
| | LRP5 | Uncharacterized protein. (1516 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (392 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1368 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | HEYL | Hes related family bHLH transcription factor with YRPW motif like. (321 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa) |
| | LOC101962660 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (824 aa) |
| | E2F2 | E2F transcription factor 2. (432 aa) |
| | FRAT1 | FRAT regulator of WNT signaling pathway 1. (277 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (252 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (711 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (271 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (430 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (593 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1192 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa) |
| | NOTCH1 | Notch receptor 1. (2466 aa) |
| | SP1 | Sp1 transcription factor. (788 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | GALK2 | Galactokinase 2. (458 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa) |
| | NOTCH2 | Notch receptor 2. (2364 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (606 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1256 aa) |
| | NOTCH3 | Notch receptor 3. (2277 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa) |
| | E2F1 | E2F transcription factor 1. (392 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (754 aa) |
| | Map2k2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (498 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (899 aa) |
| | Pik3r2 | Uncharacterized protein. (724 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | Cdk4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa) |
| | RB1 | RB transcriptional corepressor 1. (957 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (361 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa) |
| | DLL3 | Delta like canonical Notch ligand 3. (585 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | Brca1 | Uncharacterized protein. (353 aa) |
| | CCND1 | Cyclin D1. (250 aa) |
| | I3LWF9_ICTTR | SH2 domain-containing protein. (118 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | SHC1 | SHC adaptor protein 1. (583 aa) |
| | I3M6A8_ICTTR | Uncharacterized protein. (968 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (399 aa) |
| | NCOA7 | Nuclear receptor coactivator 7. (940 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2577 aa) |
| | FRAT2 | FRAT regulator of WNT signaling pathway 2. (222 aa) |
| | APC | APC regulator of WNT signaling pathway. (2865 aa) |
| | NCOA1 | Nuclear receptor coactivator. (1442 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (514 aa) |
| | Shc2 | Uncharacterized protein. (581 aa) |
| | Csde1 | Uncharacterized protein. (555 aa) |
| | CSNK1A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (353 aa) |
| | NCOA3 | Nuclear receptor coactivator. (1413 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1334 aa) |
| | IGF1 | Insulin like growth factor 1. (166 aa) |
| | ESR2 | Estrogen receptor 2. (525 aa) |
| | Pik3cd | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (598 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (208 aa) |
| | Pik3r3 | Uncharacterized protein. (461 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | Polk | UmuC domain-containing protein. (541 aa) |
| | ENSSTOP00000027930 | Uncharacterized protein. (173 aa) |
| | LOC101975023 | CSD_1 domain-containing protein. (729 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2114 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (822 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | LOC101973038 | UmuC domain-containing protein. (265 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (717 aa) |
| | LOC101968118 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (932 aa) |
| | CEP152 | Centrosomal protein 152. (1507 aa) |
| | ENSSTOP00000024190 | Protein kinase domain-containing protein. (266 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | HEY1 | Hes related family bHLH transcription factor with YRPW motif 1. (304 aa) |
| | FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (556 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (470 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (552 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa) |
| | HES5 | Hes family bHLH transcription factor 5. (141 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa) |
| | ERAS | ES cell expressed Ras. (227 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | Rps6kb1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | AXIN2 | Axin 2. (840 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) |
| | E2F3 | E2F transcription factor 3. (460 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (162 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (336 aa) |
| | PGR | Progesterone receptor. (932 aa) |
| | LOC101958853 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (557 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | LOC101958852 | Uncharacterized protein. (579 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1363 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (715 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | HEY2 | Hes related family bHLH transcription factor with YRPW motif 2. (337 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa) |
| | Fgf4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (166 aa) |
| | JAG2 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1106 aa) |
| | Notch4 | Uncharacterized protein. (1955 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa) |
| | LOC101957545 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (328 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | Fgf2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (144 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | TCF7 | Transcription factor 7. (302 aa) |
| | LOC101965906 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (970 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1540 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (331 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa) |
