STRINGSTRING
Wasf1 Wasf1 SLC5A7 SLC5A7 EGFR EGFR RAC1 RAC1 Eif4ebp1 Eif4ebp1 SLC22A3 SLC22A3 SLC44A2 SLC44A2 SLC22A5 SLC22A5 DGKK DGKK SLC22A1 SLC22A1 MAP2K1 MAP2K1 KRAS KRAS LOC101962660 LOC101962660 DGKH DGKH SLC22A2 SLC22A2 PLD1 PLD1 AKT3 AKT3 Ralgds Ralgds DGKD DGKD PDGFRA PDGFRA CHKA CHKA PLCG1 PLCG1 CHPT1 CHPT1 SLC44A1 SLC44A1 PRKCB PRKCB MAPK8 MAPK8 GRB2 GRB2 PIK3CA PIK3CA PDPK1 PDPK1 TSC2 TSC2 RAC3 RAC3 PLA2G4E PLA2G4E SLC44A3 SLC44A3 PLA2G4D PLA2G4D PLA2G4F PLA2G4F DGKQ DGKQ MAPK1 MAPK1 PLD2 PLD2 PCYT1B PCYT1B LOC101965906 LOC101965906 GPCPD1 GPCPD1 NRAS NRAS RPS6KB2 RPS6KB2 WASF3 WASF3 Chkb Chkb RAC2 RAC2 PLPP2 PLPP2 SLC22A4 SLC22A4 PDGFB PDGFB WAS WAS Rps6kb1 Rps6kb1 ERAS ERAS SLC44A4 SLC44A4 JUN JUN SLC44A5 SLC44A5 Plpp3 Plpp3 JMJD7 JMJD7 PIP5K1B PIP5K1B PDGFRB PDGFRB LOC101968118 LOC101968118 PLPP1 PLPP1 PRKCG PRKCG PIK3R1 PIK3R1 DGKG DGKG LOC101975023 LOC101975023 LYPLA1 LYPLA1 ENSSTOP00000028389 ENSSTOP00000028389 AKT1 AKT1 HRAS HRAS PCYT1A PCYT1A Pik3r3 Pik3r3 Pik3cd Pik3cd SOS1 SOS1 DGKB DGKB MAPK9 MAPK9 DGKA DGKA Csde1 Csde1 PIP5K1C PIP5K1C PLA2G4A PLA2G4A ENSSTOP00000031635 ENSSTOP00000031635 DGKZ DGKZ MTOR MTOR PIP5K1A PIP5K1A Pla2g4b Pla2g4b MAPK3 MAPK3 PLA2G4C PLA2G4C PIK3CB PIK3CB DGKI DGKI PDGFC PDGFC MAPK10 MAPK10 Pik3r2 Pik3r2 Map2k2 Map2k2 AKT2 AKT2 FOS FOS PRKCA PRKCA WASF2 WASF2 PDGFA PDGFA TSC1 TSC1 RHEBL1 RHEBL1 PDGFD PDGFD RHEB RHEB Hif1a Hif1a SP1 SP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Wasf1WH2 domain-containing protein. (559 aa)
SLC5A7Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa)
EGFRReceptor protein-tyrosine kinase. (1192 aa)
RAC1Rac family small GTPase 1. (211 aa)
Eif4ebp1Uncharacterized protein. (118 aa)
SLC22A3Solute carrier family 22 member 3. (540 aa)
SLC44A2Solute carrier family 44 member 2; Belongs to the CTL (choline transporter-like) family. (706 aa)
SLC22A5Solute carrier family 22 member 5. (557 aa)
DGKKDiacylglycerol kinase. (1110 aa)
SLC22A1Solute carrier family 22 member 1. (550 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
LOC101962660Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (824 aa)
DGKHDiacylglycerol kinase. (1216 aa)
SLC22A2Solute carrier family 22 member 2. (554 aa)
PLD1Phospholipase. (1037 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
RalgdsUncharacterized protein. (894 aa)
DGKDDiacylglycerol kinase. (1170 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
CHKACholine kinase alpha. (411 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
CHPT1Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (371 aa)
SLC44A1Solute carrier family 44 member 1; Belongs to the CTL (choline transporter-like) family. (718 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (556 aa)
TSC2TSC complex subunit 2. (1745 aa)
RAC3Rac family small GTPase 3. (185 aa)
PLA2G4EPhospholipase A2. (876 aa)
SLC44A3Solute carrier family 44 member 3; Belongs to the CTL (choline transporter-like) family. (652 aa)
PLA2G4DPhospholipase A2. (827 aa)
PLA2G4FPhospholipase A2. (840 aa)
DGKQDiacylglycerol kinase. (924 aa)
MAPK1Mitogen-activated protein kinase. (331 aa)
PLD2Phospholipase. (933 aa)
PCYT1BPhosphate cytidylyltransferase 1, choline, beta. (369 aa)
LOC101965906Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (970 aa)
GPCPD1Glycerophosphocholine phosphodiesterase 1. (668 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
WASF3WASP family member 3. (502 aa)
ChkbCholine kinase beta. (402 aa)
RAC2Rac family small GTPase 2. (192 aa)
PLPP2Phospholipid phosphatase 2. (287 aa)
SLC22A4Solute carrier family 22 member 4. (553 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (211 aa)
WASWASP actin nucleation promoting factor. (503 aa)
Rps6kb1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
ERASES cell expressed Ras. (227 aa)
SLC44A4Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (709 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
SLC44A5Solute carrier family 44 member 5; Belongs to the CTL (choline transporter-like) family. (689 aa)
Plpp3acidPPc domain-containing protein. (312 aa)
JMJD7Jumonji domain containing 7. (316 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (452 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1112 aa)
LOC101968118Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (932 aa)
PLPP1Phospholipid phosphatase 1. (285 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
DGKGDiacylglycerol kinase. (791 aa)
LOC101975023CSD_1 domain-containing protein. (729 aa)
LYPLA1Lysophospholipase 1. (230 aa)
ENSSTOP00000028389Uncharacterized protein. (113 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PCYT1APhosphate cytidylyltransferase 1, choline, alpha. (367 aa)
Pik3r3Uncharacterized protein. (461 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1334 aa)
DGKBDiacylglycerol kinase. (802 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
DGKADiacylglycerol kinase. (799 aa)
Csde1Uncharacterized protein. (555 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (663 aa)
PLA2G4APhospholipase A2. (750 aa)
ENSSTOP00000031635Uncharacterized protein. (493 aa)
DGKZDiacylglycerol kinase. (1154 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2577 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (537 aa)
Pla2g4bPhospholipase A2. (774 aa)
MAPK3Mitogen-activated protein kinase. (361 aa)
PLA2G4CPhospholipase A2 group IVC. (571 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
DGKIDiacylglycerol kinase. (960 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (344 aa)
MAPK10Mitogen-activated protein kinase. (492 aa)
Pik3r2Uncharacterized protein. (724 aa)
Map2k2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (498 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa)
WASF2WASP family member 2. (497 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
TSC1TSC complex subunit 1. (1164 aa)
RHEBL1RHEB like 1. (183 aa)
PDGFDPlatelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (370 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
Hif1aUncharacterized protein. (821 aa)
SP1Sp1 transcription factor. (788 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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